1,634 research outputs found
Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans
No full textObjective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis. Methods: In 50 patients, seroreactivity to different antigens of Borrelia burgdorferi sensu lato was analyzed by a recombinant immunoblot test (IB) in consecutive serum samples from a minimum follow-up period of 1 year. Antigens in the IgG test were decorin- binding protein A, internal fragment of p41 (p41i), outer surface protein C (OspC), p39, variable major protein-like sequence expressed (VlsE), p58 and p100; those in the IgM test were p41i, OspC and p39. Immune responses were correlated with clinical and treatment-related parameters. Results: Positive IB results were found in 50% before, in 57% directly after therapy and in 44% by the end of the follow-up for the IgG class, and in 36, 43 and 12% for the IgM class. In acute and convalescence phase sera, VlsE was most immunogenic on IgG testing 60 and 70%), and p41i (46 and 57%) and OspC (40 and 57%) for the IgM class. By the end of the follow-up, only the anti-p41i lgM response was significantly decreased to 24%. Conclusions: No correlation was found between IB results and treatment-related parameters. Thus, immunoblotting does not add to the clinical assessment of EM patients after treatment. Copyright (c) 2008 S. Karger AG, Basel
Paul Rudolph. Bond Centre
No full textIl Bond Centre di Paul Rudolph ad Hong Kong è un complesso di due torri gemelle connesse con un grande basamento. E' particolarmente interessante per il modo in cui articola lo spazio urbano dell'attacco a terra. Esso rivela la concezione di Rudolph dell'edificio alto costituito una parte urbana sottostante (village in the city). Esso viene comparato ad altri progetti di Rudolph ed alle teorie di Rem Koolhaas sugli edifici alti.The Bond Centre is one of the first big skyscrapers in Hong Kong. It is actually a twin towers complex very peculiar in the manner it relates to the urban space of the city. It unfolds Rudolph's ideas about the tall buildings and their link to the city. The author relates this building with other projects by Rudolph. In the last part Rudolph's ideas are compared with similar theories by Rem Koolhaas
Does a Bomber\u27s Signature Exist Within a Group?: The Search for an Answer Through the Eric Rudolph Cases
No full textThe thesis purpose was to prove that a bomber’s signature does not exist within a group by researching the Eric Rudolph cases. Eric Rudolph was introduced to extreme religions and ideologies through his mother Patricia Rudolph from a very young age. Eric started to accept and identify with the white supremacist and anti-Semitic thought processes of these groups, particularly Christian Identity. Rudolph had a brief stint in the Army, but became unruly when he failed at becoming an Army Ranger and eventually was discharged due to marijuana use. Rudolph moved back to North Carolina and lived “off the grid” by paying and receiving only cash as well as never applying for a social security number. Rudolph committed a total of four bombings with six devices in a span on eighteen months. The bombings resulted in numerous victims and one murder. Rudolph was eventually identified as a subject by the information given by his family and acquaintances as well as a student at the University of Alabama at Birmingham identifying him leaving the scene of the bombing and recording his licenses plate number. The manhunt lasted five years and Rudolph was eventually captured by a rookie Murphy police officer. He was convicted of all four bombings as well as the murder and will serve four consecutive life sentences. Only one similarity was found between Rudolph and another Christian Identity member, but overall there was no significant results to verify a bomber’s signature exist within a group based on these cases
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