303,343 research outputs found
Chronic kidney disease for the primary care clinician
No full textCITATION: Davids, M., & Chothia, M. 2019. Chronic kidney disease for the primary care clinician. South African Family Practice, 61(5):19-24. doi:10.4102/safp.v61i5.4941The original publication is available at https://safpj.co.za/index.php/safpjENGLISH ABSTRACT: An epidemic of chronic kidney disease (CKD) is being experienced in South Africa. This is driven by a heavy burden of infections, non-communicable diseases, pregnancy-related diseases and injuries. The serious long-term complications of CKD include end-stage renal disease, heart disease and stroke. Competing priorities such as the high burden of HIV, tuberculosis and other infections, unemployment and poverty result in serious constraints to providing comprehensive renal care, especially in the public healthcare sector. The prevention and early detection of CKD by primary care practitioners is therefore of utmost importance. Annual screening is recommended for patients at high risk of developing CKD. This involves checking blood pressure, urine dipstick testing for albuminuria or proteinuria and estimating the glomerular filtration rate from serum creatinine concentrations. In patients with established CKD, renoprotective measures are indicated to arrest or slow down the loss of renal function. These patients are at high risk of cardiovascular disease and close attention should be paid to optimally managing their risk factors.https://safpj.co.za/index.php/safpj/article/view/4941Publisher’s versio
Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report
No full textCITATION: Chothia, M. Y., et al. 2019. Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report. Journal of Medical Case Reports, 12:381, doi:10.1186/s13256-018-1938-y.The original publication is available at https://jmedicalcasereports.biomedcentral.comBackground: Hypernatremia is a very common electrolyte disorder and is frequently encountered in out-patient as
well as in-hospital settings. We describe an adult who was found to have unexplained relative polycythemia and
episodic hypernatremia. A diagnosis of idiopathic hypodipsic-hypernatremia syndrome was made and the patient
was managed with a water-drinking schedule.
Case presentation: A 24-year-old South African-Indian man was found to have polycythemia in association with
episodes of hypernatremia. Investigations indicated that he had relative polycythemia. He experienced no thirst at a
time when his serum sodium concentration was found to be 151 mmol/L. Further testing indicated that his renal
response to arginine vasopressin was intact and magnetic resonance imaging of his brain revealed no
hypothalamic lesions. A diagnosis of idiopathic hypodipsic-hypernatremia syndrome was made and he was
managed with a water-drinking schedule that corrected his hypernatremia.
Conclusion: Hypodipsia should always be considered when a patient without physical or cognitive disability
presents with unexplained episodic hypernatremia or with relative polycythemia.https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-018-1938-yPublisher's versio
Antibody structure, prediction and redesign.
No full textSo far the difficulty to predict the structure of the third hypervariable loop of the heavy chain of antibodies has represented the main limitation in modelling the complete antigen binding site. We carefully analysed all available structures of immunoglobulins searching for rules relating the loop conformation to its amino acid sequence. Here, we analyse the conformation of this loop and show that we are able to predict the conformation of the ten residues proximal to the framework. The conformation of the remaining residues of loops longer than 10 residues can also be predicted in many cases. This, combined with the previously defined canonical structures for the other five hypervariable loops, is an important step toward the prediction of the complete immunoglobulin antigen-binding site. We exemplify our prediction protocol using three known immunoglobulin structures as test cases
Landsat MSS classification of fire fuel types in Wood Buffalo National Park, northern Canada
No full textJ1: Global Ecology & Biogeography Letters; M3: Article; Milne, David Franklin, Steven E. Wilson, Bradley A. Ghitter, Geoff Heathcott, Mark McCaffrey, Thomas M. Ow, Charlotte F. Y.; Source Information: Mar1994, Vol. 4 Issue 2, p33; Subject Term: FOREST fires; Author-Supplied Keyword: Canada (Wood Buffalo National Park); Author-Supplied Keyword: Forest fire; Author-Supplied Keyword: Fuel type classification; Author-Supplied Keyword: Landsat data; Number of Pages: 0p; Document Type: Articl
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
The long-wavelength view of GG Tau A: rocks in the ring world
No full textWe present the first detection of GG Tau A at centimetre wavelengths, made with the Arcminute Microkelvin Imager Large Array at a frequency of 16 GHz (λ = 1.8 cm). The source is detected at >6 σrms with an integrated flux density of S16GHz = 249 ± 45 µJy. We use these new centimetre-wave data, in conjunction with additional measurements compiled from the literature, to investigate the long-wavelength tail of the dust emission from this unusual protoplanetary system. We use an MCMC-based method to determine maximum likelihood parameters for a simple parametric spectral model and consider the opacity and mass of the dust contributing to the microwave emission. We derive a dust mass of Md ~ 0.1 Msun, constrain the dimensions of the emitting region and find that the opacity index at λ > 7 mm is less than unity, implying a contribution to the dust population from grains exceeding ~4 cm in size. We suggest that this indicates coagulation within the GG Tau A system has proceeded to the point where dust grains have grown to the size of small rocks with dimensions of a few centimetres. Considering the relatively young age of the GG Tau association in combination with the low derived disc mass, we suggest that this system may provide a useful test case for rapid core accretion planet formation models
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Letter from Cedrick M. Shimo to the Office of Redress Administration, June 4, 1991
No full textA letter from Cedrick M. Shimo to the Office of Redress Administration arguing that John Y. Udaka is entitled to a redress payment.These materials are from box 73 and 74 of the Frank Chin Papers. The Frank Chin Papers contain personal and professional correspondence between Frank Chin and Michi Weglyn relating to particular projects on which either author was working as well as files related to the Day of Remembrance Tribute to Michi Weglyn
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
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