7,279 research outputs found
Young-suk Cho
No full text학위논문(석사)--아주대학교 일반대학원 :의학과,2009. 8cytokine은 신호 전달 단백의 하나로 이 분자들은 호르몬처럼 세포 간 정보 전달에 광범위하게 이용된다. TNF-α는 염증과 관련되어 급성 반응을 나타내며 IL-6은 특정 미생물 물질에 반응하여 분비되어 proinflammatory cytokine으로 작용한다. 대개 이들의 level이 높은 경우는 악관절 질환의 증상과 큰 연관이 있다고 알려져 있다. 이들은 관절과 관련된 골 및 연골의 파괴를 촉진하여 악관절 질환과 관련하여 동통과 관절잡음 또는 개구량의 감소 등과 같은 임상적 증상과 징후를 나타내므로 악관절 질환 중 관절 내장증과 골관절염등과 주로 연관이 있다고 알려져 있다.
본 연구의 목적은 관절낭액 내의 TNF-α와 IL-6의 분석을 통하여 두 물질의 농도와 동통 발생, 개구제한, 악관절 잡음 등의 임상 증상과의 상관 관계를 규명하는데 있다. 연구 재료는 5명의 정상인을 대조군으로, 아주대학 병원 치과에 동통과 개구제한을 주소로 내원하여 악관절 질환으로 진단된 환자 중 악관절 세척술의 적응증이 되는 24명을 실험군으로 하여 세척술 시 추출된 관절낭액을 이용하였다.국문요약 ⅰ
차례 ⅱ
표 차례 ⅲ
Ⅰ. 서론 1
Ⅱ. 연구대상 및 방법 4
A. 환자와 임상적 평가 기준 4
B. 실험 방법 5
1. 악관절 낭액의 추출과 수집 5
2. 분석 방법 5
3. 자료 분석 6
Ⅲ. 결과 7
A. 정상군과 비정상군의 비교 9
B. 비정상군 내의 급성 환자와 만성 환자의 수치 비교 10
C. 비정상군 중 개구제한이 있는 사람과 정상군과의 수치 비교 11
D. 비정상군 중 개구제한이 있는 경우 만성과 급성 환자의 수치 비교 12
E. 비정상군 중 술전에 관절잡음이 있는 사람과 정상군 비교 13
F. 비정상군 중 관절잡음이 있는 사람의 만성과 급성의 수치 비교 14
Ⅳ. 총괄 및 고찰 15
Ⅴ. 결론 19
참고문헌 20
ABSTRACT 27Maste
Earth abundant metal-based heterojunction electrode for an enhancement of reactive chlorine species generation.
No full text2
Forecasting carbon futures volatility using GARCH models with energy volatilities
No full textThis article examines the volatility forecasting abilities of three approaches: GARCH-type model that uses carbon futures prices, an implied volatility from carbon options prices, and the k-nearest neighbor model. Based on the results, we document that GARCH-type models perform better than an implied volatility and the k-nearest neighbor model. This result suggests that carbon options have little information about carbon futures due to their low trading volume. We also investigate whether the volatilities of energy markets, i.e., Brent oil, coal, natural gas, and electricity, forecast following day's carbon futures volatility. According to the results, we suggest that Brent oil, coal, and electricity may be used to forecast the volatility of carbon futures. (C) 2013 Elsevier B.V. All rights reserved
Josef Suk as a Author of the Piano Arrangement of the Works by Antonín Dvořák
No full textThe Paper treats of the Relation between Josef Suk as an Author of the Piano Arrangements to the Concert Ouverture V přírodě op. 91, Othello op. 93 and Te Deum op. 103 by Antonín Dvořák
1H NMR Spectroscopy Profiling of Metabolic Reprogramming of Chinese Hamster Ovary Cells upon a Temperature Shift during Culture
No full textWe report an NMR based approach to determine the metabolic reprogramming of Chinese hamster ovary cells upon
a temperature shift during culture by investigating the extracellular cell culture media and intracellular metabolome of
CHOK1 and CHO-S cells during culture and in response to cold-shock and subsequent recovery from hypothermic
culturing. A total of 24 components were identified for CHOK1 and 29 components identified for CHO-S cell systems
including the observation that CHO-S media contains 5.6 times the level of glucose of CHOK1 media at time zero.
We confirm that an NMR metabolic approach provides quantitative analysis of components such as glucose and
alanine with both cell lines responding in a similar manner and comparable to previously reported data. However,
analysis of lactate confirms a differentiation between CHOK1 and CHO-S and that reprogramming of metabolism in
response to temperature was cell line specific. The significance of our results is presented using principal component
analysis (PCA) that confirms changes in metabolite profile in response to temperature and recovery. Ultimately, our
approach demonstrates the capability of NMR providing real-time analysis to detect reprogramming of metabolism
upon cellular perception of cold-shock/sub-physiological temperatures. This has the potential to allow manipulation of
metabolites in culture supernatant to improve growth or productivity
(1+1)차원에서 적분가능한 모델의 산란행렬
No full text학위논문(박사) - 한국과학기술원 : 물리학과, 1993.8, [ [ii], 53 p. ]한국과학기술원 : 물리학과
최소 상사장론에서 용융계수
No full text학위논문(석사) - 한국과학기술원 : 물리학과, 1989.2, [ [ii], 43, [2] p. ; ]In vector-like conformal field theory (), all fusion coefficients are determined by solving second-order differential equations with monodromy condition and crossing symmetry. In this paper we extend this idea to chiral theory, and some fusion coefficients are expressed as the direct product of those of vector-like theory with undertimined sign ambiguity. But others some of fusion coefficients cannot be obtained by solving second order differential equations. These are explicitly demonstrated in three-state Potts Model (D, A).한국과학기술원 : 물리학과
Optimum Design of Quenching Capacitor Integrated Silicon Photomultipliers for TOF-PET Application
No full textAbstractThe prototype SiPM was designed and fabricated for MRI compatible PET using the customized CMOS process at National Nanofab Center in KAIST. The SiPM was designed to have a size of 3x3 mm2 composed of micro-cells of 65x65μm2 with a fill factor of 68%. The size of a micro-cell was determined by optimization between the photon detection efficiency (PDE) and the dynamic range for the photons of 511 keV from LYSO crystal. In the micro-cell structure, a specially designed quenching capacitor (QC) is added parallel to quenching resistor using the Metal-Insulator-Metal (MIM) process. This QC integrated SiPMs (QC-SiPM) was devised to realize rapid response of output pulses and to enhance the timing resolution of SiPM. Coincidence timing resolution of PET detectors depends on the output pulse shapes which are the convolution of the intrinsic pulse shape of scintillation crystals and the single photon pulse shape at the micro-cell in a SiPM. A quenching capacitor parallel to a quenching resistor provides a fast current path at the beginning stage of avalanche process, than reduces rising time of single photon pulse shape. In this study the rise time of the QC-SiPM signal was analyzed to be 22.5ns while that for the regular SiPM was 34.3ns
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