423 research outputs found
Cardiogenic shock centres for optimal care coordination and improving outcomes in cardiogenic shock
No full textAddressing comorbidities in heart failure: When feeling better and living longer go in the same direction
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Atrial fibrillation before and after transcatheter aortic valve implantation: an intertwine between survival and quality of life
No full textQuality of life in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: tools and evidence
No full text: Aortic stenosis is the most prevalent valvular heart disease requiring intervention, especially in the elderly population. Surgical aortic valve replacement and transcatheter aortic valve implantation (TAVI) are well established treatment options for symptomatic patients with severe aortic stenosis, as they provide a significant survival benefit. Aortic stenosis may have an important impact on patients' quality of life (QoL). However, advanced age, comorbidities and frailty may limit the beneficial effect of aortic stenosis interventions in terms of QoL. Current guidelines mention the importance of frailty and avoiding the futility of interventions, but lack specific indications about decision-making. Also, there are limited data on how to specifically assess QoL in aortic stenosis patients since the most used questionnaires are validated in different populations (i.e. heart failure). The aim of this review is to summarize all the available tools for QoL assessment in patients with aortic stenosis; to report current evidence on the impact of TAVI on QoL; and to discuss the role of frailty and comorbidities in this setting
Medical therapy of cardiogenic shock: Contemporary use of inotropes and vasopressors
No full text: Cardiogenic shock is a primary cardiac disorder that results in both clinical and biochemical evidence of tissue hypoperfusion and can lead to multi-organ failure and death depending on its severity. Inadequate cardiac contractility or cardiac power secondary to acute myocardial infarction remains the most frequent cause of cardiogenic shock, although its contribution has declined over the past two decades, compared with other causes. Despite some advances in cardiogenic shock management, this clinical syndrome is still burdened by an extremely high mortality. Its management is based on immediate stabilization of haemodynamic parameters so that further treatment, including mechanical circulatory support and transfer to specialized tertiary care centres, can be accomplished. With these aims, medical therapy, consisting mainly of inotropic drugs and vasopressors, still has a major role. The purpose of this article is to review current evidence on the use of these medications in patients with cardiogenic shock and discuss specific clinical settings with indications to their use
Defalcation of European Union Budget in the Romanian Criminal Law
Full text linkOne of the goals for Romania, after the 1st January 2007, was to protect the financial interests of the European Union to fight against fraud, corruption and other illegal activities. In order to achieve this target, the legal framework has been completed by the Law no. 161/2003 which introduced the article no. 182 in the text of the Law no. 78/2000 regarding prevention, discovery and punishing the corruption acts. The author analyses this new article and he develops the two constitutive elements (actus reus, mens rea), the objective and subjective aspects of the analyzed crime, the ways, the legal punishments applicable to this crime.fraud, financial interests, spending, incomes, actus reus, mens rea, legal punishments.
Safety and Efficacy of Istaroxime for Patients with Acute-Heart-Failure-Related Pre-cardiogenic Shock - A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study (SEISMiC)
No full textWe examined the effects of istaroxime in patients hospitalized for acute heart failure (AHF) related Society for Cardiovascular Angiography and Interventions (SCAI) stage B pre-cardiogenic shock (CS)
Niemożliwe „stawanie-się-mężczyzną” Ovidiu Anemţoaicei O propunere de corpo-etică feministă Masculinităţi și filosofia diferenţei sexuale
Full text linkIn this contribution, the author attempts to critically discuss main issues referred to by Ovidiu Anemţoaicei in his book Male Bodies and Sexual Difference.A Proposal for a Feminist Corporeo-Ethics (published in Romanian, 2017). Anemţoaicei’s is a new take on relations between male bodies, men, and masculinity that endeavours to implement, in the field of men’s studies, the notion of sexual difference as understood in Luce Irigaray’s thought. His readings of Irigaray’s works lead Anemţoaicei to a postDeleuzian interpretation of the concept of “becoming-man,” which allows him to outline a framework of newly-defined masculinity, a non-hegemonic ethical stance on female and male corporeality.In this contribution, the author attempts to critically discuss main issues referred to by Ovidiu Anemţoaicei in his book Male Bodies and Sexual Difference.A Proposal for a Feminist Corporeo-Ethics (published in Romanian, 2017). Anemţoaicei’s is a new take on relations between male bodies, men, and masculinity that endeavours to implement, in the field of men’s studies, the notion of sexual difference as understood in Luce Irigaray’s thought. His readings of Irigaray’s works lead Anemţoaicei to a postDeleuzian interpretation of the concept of “becoming-man,” which allows him to outline a framework of newly-defined masculinity, a non-hegemonic ethical stance on female and male corporeality
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