581 research outputs found

    Computing correlations between six versions of Ad Incorrupta (c. 1145-1153) copied with Gratian's Decretum (c. 1139)

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    In this project, the goal was to determine the differences found between the six manuscripts translated and the Montecassino manuscript believed to be the first one. The Montecassino manuscript was written by Nicholas Maniacutis, a medieval Roman scholar. The text was copied widely through Europe believing to begin around 1145 until 1400. Although the scribes all used the same document to translate, this project takes a look at the differences that each translation had from the original document

    De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.

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    (The American Journal of Human Genetics 103, 666–678; November 1, 2018) In the version of this article originally published online, Qinghe Xing's name was misspelled as Qinghe Xin. Also, Azita Sadeghpour, Erica E. Davis, and Nicholas Katsanis (all at Center for Human Disease Modeling, Duke University Medical Center, Durham, NC 27701, USA) and the Task Force for Neonatal Genomics were omitted from the author list. The members of the Task Force for Neonatal Genomics are as follows: Alexander Allori, Misha Angrist, Patricia Ashley, Margarita Bidegain, Brita Boyd, Eileen Chambers, Heidi Cope, C. Michael Cotten, Theresa Curington, Erica E. Davis, Sarah Ellestad, Kimberley Fisher, Amanda French, William Gallentine, Ronald Goldberg, Kevin Hill, Sujay Kansagra, Nicholas Katsanis, Sara Katsanis, Joanne Kurtzberg, Jeffrey Marcus, Marie McDonald, Mohammed Mikati, Stephen Miller, Amy Murtha, Yezmin Perilla, Carolyn Pizoli, Todd Purves, Sherry Ross, Azita Sadeghpour, Edward Smith, and John Wiener. The authors apologize for these omissions

    Analysis data and code for "Estimated transmissibility and impact of SARS-CoV-2 Variant of Concern 202012/01 in England"

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    Analysis data and code for: Estimated transmissibility and impact of SARS-CoV-2 Variant of Concern 202012/01 in England Nicholas G. Davies1†, Sam Abbott1*, Rosanna C. Barnard1*, Christopher I. Jarvis1*, Adam J. Kucharski1*, James D. Munday1*, Carl A. B. Pearson1*, Timothy W. Russell1*, Damien C. Tully1*, Alex D. Washburne2*, Tom Wenseleers3*, Amy Gimma1, William Waites1, Kerry LM Wong1, Kevin van Zandvoort1, Justin D. Silverman4, CMMID COVID-19 Working Group1, The COVID-19 Genomics UK (COG-UK) Consortium5, Karla Diaz-Ordaz6, Ruth Keogh6, Rosalind M. Eggo1, Sebastian Funk1, Mark Jit1, Katherine E. Atkins1,7, W. John Edmunds1 1. Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK. 2. Selva Analytics LLC, Bozeman, MT, USA. 3. Lab of Socioecology and Social Evolution, KU Leuven, Leuven, Belgium. 4. College of Information Science and Technology, Pennsylvania State University, University Park, PA, USA. 5. https://www.cogconsortium.uk 6. Centre for Statistical Methodology, London School of Hygiene and Tropical Medicine, London, UK. 7. Centre for Global Health, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK † Corresponding author. E-mail: [email protected] * Equal contribution; listed alphabetically https://www.medrxiv.org/content/10.1101/2020.12.24.20248822v

    Explaining Myanmar's Regime Transition: The Periphery is Central

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    In 2010, Myanmar (Burma) held its first elections after 22 years of direct military rule. Few compelling explanations for this regime transition have emerged. This article critiques popular accounts and potential explanations generated by theories of authoritarian ‘regime breakdown’ and ‘regime maintenance’. It returns instead to the classical literature on military intervention and withdrawal. Military regimes, when not terminated by internal factionalism or external unrest, typically liberalise once they feel they have sufficiently addressed the crises that prompted their seizure of power. This was the case in Myanmar. The military intervened for fear that political unrest and ethnic-minority separatist insurgencies would destroy Myanmar’s always-fragile territorial integrity and sovereignty. Far from suddenly liberalising in 2010, the regime sought to create a ‘disciplined democracy’ to safeguard its preferred social and political order twice before, but was thwarted by societal opposition. Its success in 2010 stemmed from a strategy of coercive state-building and economic incorporation via ‘ceasefire capitalism’, which weakened and co-opted much of the opposition. Having altered the balance of forces in its favour, the regime felt sufficiently confident to impose its preferred settlement. However, the transition neither reflected total ‘victory’ for the military nor secured a genuine or lasting peace

    A study of identity, privilege, and disquieting power: The story of Idi Amin

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    Reviewed Work: The Last King of Scotland (2006) director Kevin Macdonald. Reviewer: Prof. Fayth M. Parks Reviews the film, The Last King of Scotland directed by Kevin Macdonald (2006). This is an intense film with an outstanding portrayal of Idi Amin, the legendary and infamous president of Uganda. Director Kevin Macdonald mixes fact with fiction in this film adaptation of British author Giles Foden\u27s (1998) best selling novel. The film foregrounds the story of Scottish doctor Nicholas Garrigan\u27s awakening to the complex and brutal reality that colonial occupation has left as its legacy to Africa. This movie is beautifully filmed on location in Uganda. The texture of urban and rural community life are presented in the film. Macdonald does an exceptional piece of work illustrating the fear and insecurity that became a way of life for Ugandans under Amin\u27s government as thousands of people disappeared. The character Garrigan awakens to the brutal reality and tries to escape Uganda alive. Idi Amin\u27s dissolution to evil is essential to see in this film. The story captures the imagination and mesmerizes the viewer. Essentially, the evil that transformed Amin\u27s character is wickedness that lives on in the evil deeds of others. (PsycINFO Database Record (c) 2016 APA, all rights reserved

    Big Data, Big Libraries, Big Problems?: the 2014 LibTech Anti-talk?

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    The desire to create automatons is a familiar theme in human history, and during the age of the Enlightenment mechanical automatons became not only an “emblem of the cosmos”, but a symbol of man’s confidence that he would unlock nature’s greatest mysteries and fully harness her power. And yet only a century later, automatons had begun to represent human repression and servitude, a theme later picked up by writers of science fiction. Man’s confidence undeterred, the endgame of the modern scientific and technological mindset, or MSTM, seems to be increasingly coming into view with the rise of “information technology” in general and “Big data” in particular. Along with those who wield them, these can be seen as functioning together as a “mechanical muse” of sorts – surprisingly alluring – and, like a physical automaton can serve as a symbol – a microcosm – of what the MSTM sees (at the very least in practice) as the cosmic machine, our “final frontier”. And yet, individuals who unreflectively participate in these things – giving themselves over to them and seeking the powers afforded by the technology apart from technology’s rightful purposes – in fact yield to the same pragmatism and reductionism those wielding them are captive to. Thus, they ultimately nullify themselves philosophically, politically, and economically – their value increasingly being only the data concerning their persons, and its perceived usefulness. Likewise libraries, the time-honored place of, and symbol for, the intellectual flowering of the individual, will, insofar as they spurn the classical liberal arts (with the idea that things are intrinsically good, and in the case of humans, special as well) in favor of the alluring embrace of MSTM-driven “information technology” and Big data - unwittingly contribute to their irrelevance and demise as they find themselves increasingly less needed, valued, wanted. Likewise for the liberal arts as a whole, and in fact history itself, if the acid of a “science” untethered from what is, in fact, good (intrinsically), continues to gain strengt

    When do special interests run rampant ? disentangling the role in banking crises of elections, incomplete information, and checks and balances

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    The author investigates the political determinants of government decisions that benefit special interest groups - especially government decisions to deal with banking crises. He finds that the better informed the voters, the more proximate elections, and the larger the number of political veto players ( conditional on the costs to voters of relevant policy decision), the smaller the government's fiscal transfer are to the financial sector and the less likely the government is to exercise forbearance in dealing with insolvent financial institutions. The results suggest that policies thatmight be appropriate for mitigating banking crises in the United States might be less effective in settings where voters are less informed, where elections are less competitive, and where there are fewer veto players, because in these settings checks and balances are missing. These policies include: a) Disseminating information about the costs of inefficient government decisions. b) Improving the structure of legislative regulatory oversight. c) Intervening early in insolvent banks. The author concludes that the more veto players there are, the less likely policies are to favor special interest groups (contrary to previous views). Moreover, the closer the elections, the less likely policies are to favor special interest groups.

    Diphtheria-like disease caused by Toxigenic Corynebacterium ulcerans strain

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    Toxigenic Corynebacterium ulcerans is an increasingly reported cause of diphtheria in the United Kingdom and is often associated with a zoonotic origin (1,2). Here, we report a case of diphtheria caused by toxigenic C. ulcerans in a woman, 51 years of age, from Scotland, UK, who was admitted to a hospital in August 2013 with a swollen, sore throat and a gray-white membrane over the pharyngeal surface. The patient had returned from a 2-week family holiday in the state of Florida, United States, before the admission and also reported recent treatment of a pet dog for pharyngitis. The patient was believed to have been vaccinated against diphtheria during childhood. She was immediately admitted to an isolation ward and treated with a combination of clindamycin, penicillin, and metronidazole

    Kepastian Hukum Perjanjian Perkawinan Yang Tidak Didaftarkan (Studi Kasus Putusan No. 1718/PDT.G/2021/PA. BTM)

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    Everything regarding marriage that has been regulated is a binding provision and must be stipulated for members of society. The legal consequences of divorce is regulated in Article 37 of Law Number 1 of 1974 regarding Marriage. In the verdict the author uses as research material, Verdict Number 1718/Pdt.G/2021/PA. Btm has determined based on the Supreme Court jurisprudence Number: 3405/K/PDT/2012 which confirms that marriage agreements that aren’t registered has no legal force. The author’s goal is to determine the legal consequences of unregistered marriage agreements. The author uses written materials as main sources to analyze with the results of  interviews. The results of the research by the author is that the Verdict Number 1718/Pdt.G/2021/PA. Btm has to be cancelled because the jurisdiction verdict number 3405/K/PDT/2012 has been cancelled and the marriage agreement between Nurevi binti Muhammad Mubazzir and Andrew Kevin Plant should be a permenant legal force. The conclusion of the research is after the issuance of Constitutional Court Decision No. 69/PUU-XIII/2015, a marriage agreement is no longer interpreted only as an agreement made before marriage, but also made during marriage

    Nicholas Culpeper and the book trade : print and the promotion of vernacular medical knowledge, 1649-65

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    This thesis examines print culture and the medical book trade during the middle decades of the seventeenth century. I examine a range of vernacular medical books which predate the publication of Nicholas Culpeper's (1616-54) translation of the London College of Physicians' first Pharmacopoeia (1618) in 1649. Culpeper's English version subjected the official medical knowledge of the professional to his caustic commentary, and launched his programme to produce 'the whol Moddel of Physick' in the vernacular. At the same time the involvement of the Fellows of the College with the book trade during the Interregnum is explored. Examination of the Stationers' Register reveal that Presidents of the College were prepared to endorse English translations of scholarly books and new works by non-Collegiate authors. Through this Register and the 'Annals' of the College I show how two astute London stationers were able to gain control of the rights to the College's Pharmacopoeia. The social relationships between Culpeper and his publishers are analysed, as well as the network of agents responsible for the production and publication of Culpeper's books and their reception. I focus on Culpeper's four principal works - his two translations of the College's Pharmacopoeia (1649 and 1653); his herbal, The English Physitian (1652); and A Directory for Midwives (1651). Their presentation (typography and page-layout), dissemination, and reception are also explored. Apparent from the early history of Culpeper's medical books is the commercialism of the book trade in the 1650s. Medical practitioners and writers exploited print culture to promote their name in the medical marketplace and create a public persona. I discuss Culpeper's activities as an editor and writer, and the fluidity of these texts in response to commercial threats from rival publishers. The development of his work through subsequent editions counters the assumption that printing preserves and fixes a text's meaning. This thesis argues that historical bibliography is essential for an understanding of a book's reception and influence, and I show how print culture was significant to the promotion of vernacular medicine in these years
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