2,013 research outputs found
Chronic kidney disease and cardiovascular risk in Taiwan: a review of the current evidence.
No full textA novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia
No full textPrevalence, awareness, efficiency of control, and target organ damage in Taiwanese patients with hypertension
No full textEfficacy and Safety of Barnidipine Compared with Felodipine in the Treatment of Hypertension in Chinese Patients
No full textImpact of heart failure and left ventricular function in long-term survival - Report of a community-based cohort study in Taiwan
No full textL'électrocardiographie haute résolution : mise au point et évaluation de l'effet pro-arythmique du flécaïnide chez le chien
Full text linkL'utilisation de l'électrocardiographie haute-résolution en toxicologie est envisagée avec la mise au point d'une technique de recueil sur le chien beagle. Les coefficients de variation intra et inter-jours des quatre paramètres enregistrés (QRSf, LAS40, RMS40, RMS) sont ensuite calculés. Nos résultats montrent que QRSf est plus répétable (1.1%) et reproductible (4.4%) que les autres paramètres et en particulier que LAS40 (respectivement 6.3 et 18.5%). Ces valeurs doivent être prises en compte dans l'interprétation des mesures obtenues lors d'examens successifs, car elles représentent la part de différence attribuable à la méthode et non au produit testé. Les effets du flécaïnide sont ainsi mis ici en évidence par l'allongement de QRSf et LAS40 (+54.9 et +174.6%, p<0.01) et la diminution de RMS40 et RMS (-83 et -65.1% p<0.01). Ils montrent la présence de potentiels ventriculaires tardifs, témoins des retards de conduction cardiaque produits par cet agent antiarythmique
Usefulness of quantifying serum KL-6 levels in the follow-up of uveitic patients with sarcoidosis
Full text linkBackground: KL-6 is a human glycoprotein secreted by type II alveolar cells in the lung, and its serum levels increase in pneumonia of various causes. We previously reported that serum KL-6 levels in uveitis patients with sarcoidosis were significantly higher than those of other uveitis patients and healthy controls. Additionally, the combined measurement of serum KL-6 and angiotensin converting enzyme (ACE) was useful for screening uveitic patients to diagnose sarcoidosis. The purpose of the present study was to investigate the clinical usefulness of quantifying serum KL-6 levels for following-up the patients with sarcoidosis. Methods: Sera were obtained from 36 uveitic patients diagnosed with sarcoidosis and the same number of healthy volunteers. To examine the influence of systemic medication, we also collected blood samples from four more sarcoidosis patients, who were systemically treated with corticosteroid or angiotensin converting enzyme (ACE) inhibitor, an anti-hypertensive drug. The serum concentration of KL-6 was measured by a human KL-6 electrochemiluminescence immunoassay (ECLIA). Results: The mean KL-6 concentrations of sarcoidosis patients and healthy controls were 449.3 +/- 66.3 (mean +/- SE) and 192.1 +/- 11.3, respectively. The average levels of serum KL-6 were significantly elevated in sarcoidosis patients compared with healthy control subjects (P < 0.001), and there were significant correlations between serum KL-6 and ACE levels in the patients with sarcoidosis (r=0.70 and P < 0.0001). Moreover, serum KL-6 concentrations were less affected by systemic corticosteroid, and unaffected by ACE inhibitory drugs in contrast to ACE levels. Conclusions: Measurement of serum KL-6 in the uveitic patients may be useful to follow-up the diagnosed sarcoidosis, as well as for diagnosing sarcoidosis, because the serum KL-6 level was well correlated with the ACE level, and less affected by systemic medication than ACE levels
Gender differences in the patterns of coronary angiography and PTCA use in a university hospital in Taiwan
No full textPrimary hypercholesterolemia, carotid atherosclerosis and insulin resistance among Chinese
No full textAn interval-censored model for predicting myopic regression after laser in situ keratomileusis
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