177,294 research outputs found
Biological indicators of coastal pollution in the Adriatic Sea comparing biomarker responses in three fish species
No full textComparative induction of liver EROD and BaPMO activities in European eel (Anguilla anguilla) by benzo[a]pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin: a laboratory study
No full textThe objective of the present study was to assess and compare the sensitivity of EROD and BaPMO enzymatic activities as biomarkers of exposure to increasing doses of benzo[a]pyrene (B[a]P) and polychlorinated 2,3,7,8-tetrachloro dibenzo-para-dioxin (2,3,7,8-TCDD) in Anguilla anguilla. Eels collected from a Mediterranean brackish environment were experimentally exposed to chemicals by intraperitoneal injection and sacrificed seven days later. Both EROD and BaPMO activities showed close dose-response relationships to chemicals, even, if the Presence of a plateau in EROD induction at concentrations above 10 mg/kg B[a]P is suggested. Higher induction occurred for EROD than for BaPMO activity in almost all the groups of exposure. Both EROD and BaPMO activities in A. anguilla appear to be suitable biomarkers to PAHs and PCDDs exposure and a higher sensitivity is suggested for EROD induction as biomarker of exposure to such chemicals
Comparative Induction of Liver EROD and BaPMO activities in European eel (Anguilla anguilla) by benzo[a]pyrene and 2.3.7.8-tetrachlorodibenzo-p-dioxin: a laboratory study.
No full textInduction of EROD activity in European eel (Anguilla anguilla) experimentally exposed to benzo(a)pyrene and b-naphtoflavone.
No full textInduction of EROD activity in European eel (Anguilla anguilla) experimentally exposed to B(a)P and βNP
No full textThe induction of liver ethoxyresorufin O-deethylase (EROD) activity was investigated in the European eel, Anguilla anguilla, collected from a Mediterranean brackish environment and experimentally exposed to benzo[a]pyrene (B[a]P) and h-naphthoflavone (BNF). Eels were injected intraperitoneally at increasing doses (0.1, 1, 10, and 50 mg/kg wet body weight) using corn oil as a carrier and sacrificed after 7 days. The main objectives of the present study are: (1) to assess of the sensitivity of EROD induction as a biomarker to polycyclic aromatic hydrocarbon (PAH) exposure; (2) to determine an EROD dose–response relationship of the contaminants used; and (3) to compare the efficiency of B[a]P and BNF as inducers of EROD activity. Results showed that both chemicals resulted in a dose-dependent EROD induction, but increases were not linear. EROD activity seemed to reach a plateau at the exposure of 10 mg/kg in both treatment groups; B[a]P was a more potent inducer than BNF was at the higher doses (10 and 50 mg/kg), while the opposite result was observed at the lower ones (0.1 and 1 mg/kg). The greatest induction occurred in eels treated with 10 mg/kg B[a]P, in which a 261-fold increase in EROD activity was observed. Results showed that EROD activity in A. anguilla is significantly induced by B[a]P and BNF exposure, responding to a wide range of concentrations of these contaminants. We infer that this tool may be suited as a diagnostic biomarker for biomonitoring PAHs pollution in Mediterranean brackish environments and further field research is suggeste
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Letter from R. R. Zellick, Assistant Trust Officer, Anglo California National Bank of San Francisco, to Joseph R. Goodman, October 2, 1942
No full textLetter from R. R. Zellick, Assistant Trust Officer at The Anglo California National Bank of San Francisco, to Joseph R. Goodman, regarding property owned by Dave Tatsuno. Zellick mentions a dispute between current tenants and Tatsuno, and that Tatsuno has asked Goodman to help locate trustworthy tenants.Personal correspondence, organizational records, government documents, publications, and other papers created or collected by Joseph R. Goodman documenting the forced removal and incarceration of Japanese Americans during World War II, as well as organized resistance to incarceration. Included in the collection are records of the Japanese Young Men's Christian Association and the Japanese American Citizens' League in San Francisco, including papers of the Japanese YMCA's executive secretary Lincoln Kanai; Sakai family papers; Goodman's correspondence to and from Japanese American incarcerees, organizations opposing forced removal and incarceration of Japanese Americans, the War Relocation Authority, and others; publications, photographs, and ephemera from the Topaz Relocation Center, where Goodman taught high school; War Relocation Authority records and publications; and newspaper clippings, pamphlets, and reports about forced removal and incarceration created by various government, religious, and civic organizations, in California and nationwide
Application of a multimarker approach for the assessment of TNT-exposure in fish: a case study in the Tremiti Islands Marine protected area
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