177,077 research outputs found
Effect on Blood Pressure Control of Switching from Valsartan Monotherapy to Losartan/Hydro-Chlorothiazide in Asian Patients with Hypertension: Results of a Multicentre Open-Label Trial
No full textStudy design: An open- label, multicentre study was conducted to evaluate the antihypertensive efficacy of a 4- week course of losartan 50 mg plus hydrochlorothiazide 12.5 mg in Asian patients with essential hypertension whose blood pressure had previously been treated with but not controlled by valsartan 80 mg. Methods: A total of 237 eligible patients with mean trough sitting diastolic blood pressure SiDBP) 95 - 115 mmHg and a mean trough sitting systolic blood pressure ( SiSBP) 90 mmHg and who were not excluded for other reasons were then switched to a single-tablet formulation of losartan 50 mg/ hydrochlorothiazide 12.5 mg combination once daily for a further 4 weeks. Results: Mean SiDBP ( study primary endpoint) at the end of combination therapy was reduced to 86.9 mmHg from 95.2 mmHg. SiSBP ( study secondary endpoint) was reduced to 132.6 mmHg from 140.7 mmHg. Mean reductions after switching from valsartan 80 mg to losartan 50 mg/ hydrochlorothiazide 12.5 mg were thus 8.3 and 8.1 mmHg for SiDBP and SiSBP , respectively ( p 99%. Conclusion: These results demonstrate that in Asian patients who do not reach the goal of mean trough SiDBP <= 90 mmHg with valsartan monotherapy at 80 mg once-daily, switching to a single-tablet combination of losartan 50 mg/hydrochlorothiazide 12.5 mg once-daily is well tolerated , provides effective control of blood pressure and is an excellent choice to achieve blood pressure reduction goals
General Chiang Kai-shek : the builder of new China
No full textGeneral Chiang Kai-shek"Significant speeches [by General Chiang]": p. [51]-107.by Chen Tsung-hsi, Wang An-tsiang and Wang I-ting; with an introduction by Dr. Chenting T. Wang and a preface by Dr. Wang Chung-hui
Statin_after_stroke_Supplementary_appendix_20190627_TAND – Supplemental material for Does statin increase the risk of intracerebral hemorrhage in stroke survivors? A meta-analysis and trial sequential analysis
No full textSupplemental material, Statin_after_stroke_Supplementary_appendix_20190627_TAND for Does statin increase the risk of intracerebral hemorrhage in stroke survivors? A meta-analysis and trial sequential analysis by Ru Jian Jonathan Teoh, Chi-Jung Huang, Chi Peng Chan, Li-Yin Chien, Chih-Ping Chung, Shih-Hsien Sung, Chen-Huan Chen, Chern-En Chiang and Hao-Min Cheng in Therapeutic Advances in Neurological Disorders</p
Everyday stuff--Cover
No full textComic book in single section sewn into handmade paper covers. Title and author printed on front coverUNL SPEC copy--Limited ed., no. 21 of 50 copies, signed by the autho
Everyday stuff--Text
No full textComic book in single section sewn into handmade paper covers. Title and author printed on front coverUNL SPEC copy--Limited ed., no. 21 of 50 copies, signed by the autho
Topological quantum transitions in a two-band Chern insulator with n = 2
No full textBased on a two-band Chern insulator with Chern number n = 2, we study the transport properties and the topological phase transition induced by either an external magnetic field or disorder. In this paper, a characteristic topological phase transition from n = 2 to n = 0, which is in sharp contrast to the plateau-plateau transition in the integer quantum Hall effect, is observed. This unique feature of the phase transition should be ascribed to the minimal two-band feature of this high Chern insulator. We prove this result by studying the transport properties of many different geometrical structures and the evolution of the Chern number in the presence of magnetic fields and strong disorder.Physics, Condensed MatterSCI(E)[email protected]
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