124 research outputs found

    Forecast horizon of 5th – 6th – 7th long wave and short-period of contraction in economic cycles

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    The purpose of this essay is to determine the forecast horizon of the fifth, sixth and seventh long wave. As the period of each long wave can change according to the data, it has been used a deterministic approach, based on historical chronologies of USA and UK economies worked out by several scholars, to determine average timing, period and forecast error of future long waves. In addition, the analysis shows that long waves have average upwave period longer than average downwave one. This result is also confirmed by US Business Cycles that have average contractions shorter than expansions phase over time.Forecast Horizon, Long Waves, Kondratieff Waves, Business Cycles, Asymmetric Path

    Predicting strategic change of public research institutions under unstable negative growth

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    The purpose of this paper is to forecast and analyse, by a demographic perspective, the organizational behaviour of public research labs. The research focuses on the biggest Italian public research body. Demographic models of growth, based on different human resource policies, show the uncertain and retrogressive evolutionary change of Italian public research bodies that would halve their research personnel over the forecast horizon. These results provide vital information to the public management about the weaknesses and environmental threats in order to support decisions for improving the strategic change and survival of public research institutions over time.Organizational Studies, Forecasting, Public Research Institutions, Internal Demography

    A pilot prospective case series study

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    Publisher Copyright: © The Author(s) 2025.Data on direct oral anticoagulants (DOACs) in venous thrombotic antiphospholipid antibody syndrome (APS) are controversial. This pilot study aimed to assess the safety and efficacy of DOACs in APS patients requiring oral anticoagulation for venous thromboembolism (VTE) but unsuitable for treatment with vitamin K antagonists (VKAs). We performed a prospective multi-centre case-series including APS patients with previous VTE who were receiving treatment with DOACs due to ineligibility for VKAs. Main outcomes were bleeding, arterial and recurrent venous thrombotic events and all-cause death. We included 18 patients (median age 59.6 years, 66.7% women). The antiphospholipid antibody pattern was single positivity for 33.3% patients, double positivity for 33.3%, and triple positivity for 27.8%. Only one patient had seronegative APS. Apixaban, dabigatran, rivaroxaban and edoxaban were prescribed in 44.4%, 27.8%, 16.7% and 11.1% of patients, respectively. The mean follow-up was 50.1 ± 24.1 months. During the observation period, no recurrent VTE episodes or arterial thrombotic events were recorded. Four bleedings, of which 2 major, were reported. The incidence rate of bleeding was 5.3 per 100 patient-years (95% confidence interval [95%CI] 1.4–13.6). No intracranial bleedings were recorded. In conclusion, our preliminary findings may suggest DOAC as possible option for patients with venous thrombotic APS unsuitable to VKAs. Although these findings are promising, larger cohort studies are needed to confirm this finding.publishersversioninpres

    IXPE and XMM-Newton Observations of the Soft Gamma Repeater SGR 1806-20

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    Full list of the authors: Turolla, Roberto; Taverna, Roberto; Israel, Gian Luca; Muleri, Fabio; Zane, Silvia; Bachetti, Matteo; Heyl, Jeremy; Di Marco, Alessandro; Gau, Ephraim; Krawczynski, Henric; Ng, Mason; Possenti, Andrea; Poutanen, Juri; Baldini, Luca; Matt, Giorgio; Negro, Michela; Agudo, Iván; Antonelli, Lucio A.; Baumgartner, Wayne H.; Bellazzini, Ronaldo; Bianchi, Stefano; Bongiorno, Stephen D.; Bonino, Raffaella; Brez, Alessandro; Bucciantini, Niccolò; Capitanio, Fiamma; Castellano, Simone; Cavazzuti, Elisabetta; Chen, Chieng-Ting; Ciprini, Stefano; Costa, Enrico; De Rosa, Alessandra; Del Monte, Ettore; Di Gesu, Laura; Di Lalla, Niccolò; Donnarumma, Immacolata; Doroshenko, Victor; Dovčiak, Michal; Ehlert, Steven R.; Enoto, Teruaki; Evangelista, Yuri; Fabiani, Sergio; Ferrazzoli, Riccardo; Garcia, Javier A.; Gunji, Shuichi; Hayashida, Kiyoshi; Iwakiri, Wataru; Jorstad, Svetlana G.; Kaaret, Philip; Karas, Vladimir; Kislat, Fabian; Kitaguchi, Takao; Kolodziejczak, Jeffery J.; La Monaca, Fabio; Latronico, Luca; Liodakis, Ioannis; Maldera, Simone; Manfreda, Alberto; Marin, Frédéric; Marinucci, Andrea; Marscher, Alan P.; Marshall, Herman L.; Massaro, Francesco; Mitsuishi, Ikuyuki; Mizuno, Tsunefumi; Ng, C. -Y.; O'Dell, Stephen L.; Omodei, Nicola; Oppedisano, Chiara; Papitto, Alessandro; Pavlov, George G.; Peirson, Abel L.; Perri, Matteo; Pesce-Rollins, Melissa; Petrucci, Pierre-Olivier; Pilia, Maura; Puccetti, Simonetta; Ramsey, Brian D.; Rankin, John; Ratheesh, Ajay; Roberts, Oliver J.; Romani, Roger W.; Sgró, Carmelo; Slane, Patrick; Soffitta, Paolo; Spandre, Gloria; Swartz, Douglas A.; Tamagawa, Toru; Tavecchio, Fabrizio; Tawara, Yuzuru; Tennant, Allyn F.; Thomas, Nicholas E.; Tombesi, Francesco; Trois, Alessio; Tsygankov, Sergey S.; Vink, Jacco; Weisskopf, Martin C.; Wu, Kinwah; Xie, FeiRecent observations with the Imaging X-ray Polarimetry Explorer (IXPE) of two anomalous X-ray pulsars provided evidence that X-ray emission from magnetar sources is strongly polarized. Here we report on the joint IXPE and XMM-Newton observations of the soft γ-repeater SGR 1806-20. The spectral and timing properties of SGR 1806-20 derived from XMM-Newton data are in broad agreement with previous measurements; however, we found the source at an all-time low persistent flux level. No significant polarization was measured apart from the 4-5 keV energy range, where a probable detection with PD = 31.6% ± 10.5% and PA = − 17 .° 6 − 15 .° 0 + 15 .° 5 was obtained. The resulting polarization signal, together with the upper limits we derive at lower and higher energies (2-4 and 5-8 keV, respectively), is compatible with a picture in which thermal radiation from the condensed star surface is reprocessed by resonant Compton scattering in the magnetosphere, similar to what was proposed for the bright magnetar 4U 0142+61. © 2023. The Author(s). Published by the American Astronomical Society.The Imaging X-ray Polarimetry Explorer (IXPE) is a joint US and Italian mission. The US contribution is supported by the National Aeronautics and Space Administration (NASA) and led and managed by its Marshall Space Flight Center (MSFC) with industry partner Ball Aerospace (contract NNM15AA18C). The Italian contribution is supported by the Italian Space Agency (Agenzia Spaziale Italiana, ASI) through contract ASI-OHBI-2017-12-I.0, agreements ASI-INAF-2017-12-H0 and ASI-INFN-2017.13-H0, and its Space Science Data Center (SSDC) with agreements ASI-INAF-2022-14-HH.0 and ASI-INFN 2021-43-HH.0, and by the Istituto Nazionale di Astrofisica (INAF) and the Istituto Nazionale di Fisica Nucleare (INFN). This research used data products provided by the IXPE Team (MSFC, SSDC, INAF, and INFN). R.Tu., R.Ta., and G.L.I. acknowledge financial support from the Italian MUR through grant PRIN 2017LJ39LM. G.L.I. also acknowledges financial support from INAF through grant "IAF-Astronomy Fellowships in Italy 2022-(GOG)." J.H. acknowledges support from the Natural Sciences and Engineering Council of Canada and the Canadian Space Agency. M.N. acknowledges support by NASA under award No. 80GSFC21M0002. T.T. was supported by grant JSPS KAKENHI JP19H05609. H.K. and E.G. acknowledge NASA support under grants 80NSSC18K0264, 80NSSC22K1291, 80NSSC21K1817, and NNX16AC42G. We thank N. Schartel for granting us XMM-Newton Director Discretionary Time

    "Mutato nomine, de te fabula narratur". Sull'attualità delle opere letterarie

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    Il saggio affronta il nodo dell'attualità delle opere letterarie, con riferimento in particolare ai contenuti testuali, nella prospettiva scolastica di una didattica motivazionale. In sede storica, la questione dell'aggiornamento tematico delle opere letterarie è stata sollevata all'inizio della modernità letteraria, per rispondere a un'esigenza nuova di rispecchiamento del mondo contemporaneo. Si presentano diversi esempi di possibili letture attualizzanti di testi canonici otto-novecenteschi, d'impianto realistico e non; con l'avvertenza, tuttavia, di salvaguardare anche la storicità delle opere e di avvalersi, semmai, dei "classici" come "liquidi di contrasto" per conoscersi attraverso la pratica del confronto col diverso

    Food and eating in fiction since 1950 with particular reference to the writing of Angela Carter, Doris Lessing, Michele Roberts and Alice Thomas Ellis.

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    PhDEating is a fundamental activity. What people eat, how and with whom, what they feel about food, what they do or do not want to eat and why - even who they eat - are of crucial significance in any reading of human behaviour. In this thesis, I consider the diverse and complex uses of food and eating in fiction since 1950, especially that written by women. I argue both that food and eating carry much of the meaning of a novel or story and that the acts of cooking, feeding and eating depicted are inseparable from issues of power and control: individually, interpersonally, culturally, politically. My discussion centres on the writing of Angela Carter, Doris Lessing, Michele Roberts and Alice Thomas Ellis. Drawing on psychoanalytic theory, sociology, anthropology, Foucault, Bakhtin and others, the thesis aims to construct an interdisciplinary perspective which both resists reductive interpretations and emphasises the centrality, complexity and diversity of food and eating in literature in our culture. I begin with an examination of the ambiguities of maternal feeding and nurturing, moving on to explore the links between appetite, eating and sexuality. I explore cannibalism and vampirism as manifestations of oppression, but also as indicating insatiable emptiness and transgressive appetite. The body itself is crucial, and my argument considers the paradox of not eating as control/enslavement, also tracing self-starvation as a positive route towards wholeness and connection. The last part of my argument focuses on social eating, examining conventions, rituals and food itself in connection with power relations, and finally considers how we might truly speak of food and eating in the context of society as a whole

    Urban Data Governance: an Interoperability-Based Approach for Monitoring Natural Threats at Different Geographic Scales, Through Smart City Platforms

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    Publisher Copyright: © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.Monitoring, preventing and managing the impacts induced by extreme natural events requires the use of multiple and different Information Communication Technology (ICT) tools and technologies capable of collecting and processing data from various sources, and supporting public stakeholders in the planning and implementation of prompt actions. In this perspective, the availability of platforms able to harmonize, integrate and manage heterogeneous data and to create new knowledge, can constitute a valuable support. This article presents some preliminary results from the EU-funded MULTICLIMACT project, part of which is defining a reference model for customizing and adopting the ENEA Smart City Platform to inform on the severity and extent of possible impacts induced by natural threats and on possible resilience strategies. Towards that the Smart City Platform enables the interoperability between heterogeneous digital solutions monitoring natural threats at different geographic scales.Peer reviewe

    Correction: International consensus on the management of metastatic gastric cancer: step by step in the foggy landscape: Bertinoro Workshop, November 2022

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    In this article the collaborators group name “Bertinoro Workshop Working Group” was missing from the author list. The author name Heike Grabsch was incorrectly written as Heike Grabsh. William Allum36, Giulio Bagnacci21, Gian Luca Baiocchi37, Felix Berlth10, Laura Borgno38,39,40, Jimmy So Bok Yan41, Riccardo Caccialanza42,Francesco Casella2, Claudia Castelli43, Mikael Chevallay24, Simona Corso44, Paulo Matos Da Costa45, Mariagiulia Dal Cero46, Maurizio De Giuli47, Stefano De Pascale48, Annibale Donini49, Domenico D’Ugo50, Giorgio Ercolani51, Federica Filippini2, Massimo Framarini1, Ewelina Frejlich52, Uberto Fumagalli Romario48, Simone Giacopuzzi2, Silvia Giordano44, Luigina Graziosi49, Henk Hartgrink53, Arnulf H. Hölscher54, Jeesun Kim35, Tiuri Kroese55, Lourenco Laercio Gomes56, Lucio Lara Santos57, Drolaiz Liu58, Florian Lordick59, Luigi Marano20, Elisabetta Marino49, Giovanni Martinelli60, Hans-Joachim Meyer61, Silvia Ministrini34, Paul F. Mansfield62, Chiara Molinari60, Manlio Monti60, Yusef Moulla63, Magnus Nilsson64, Sara Patuzzo65, Manuel Pera46, Osvaldo Antonio Prado Castro14, Alberto Quinzii22, Ilario Giovanni Rapposelli60, Stefano Rausei66, Rossella Reddavid47, Fausto Rosa67, Riccardo Rosati68, Romina Rossi17, Giandomenico Roviello69, Julia Rudno-Rudzinska52, Michele Sacco2, Massimiliano Salati70, Paul M Schneider71, Leonardo Solaini51, Masanori Terashima72, Anna Tomezzoli43, Martina Valgiusti60, Antonio Carlos Weston73, Kielan Wojciech52, Goetze Thortsen7436Department of Surgery, Royal Marsden Hospital, London, UK 37Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy 38Chief of Surgery Department of National Cancer Institute ASSE, Uruguay 39Chief of Surgery Department Las Piedras Hospital ASSE, Uruguay 40Ex Associate Professor of General Surgery Medicine Faculty Udelar, Uruguay 41Department of Surgery, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 42Clinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy 43Section of Pathology, Department of Diagnostics and Public Health University of Verona, Verona, Italy 44Department of Oncology, Torino University, Candiolo Cancer Institute-FPO, IRCCS Italy 45Departamento de Cirurgia, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal 46Section of Gastrointestinal Surgery, Hospital Universitario del Mar, Hospital del Mar Medical Research Institute (IMIM). Department of Surgery, Universitat Autònoma de Barcelona, Barcelona, Spain 47Department of Oncology, Surgical Oncology and Digestive Surgery Unit, San Luigi University Hospital, University of Turin, Orbassano, Turin, Italy 48Department of Digestive Surgery, European Institute of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 20141 Milan, Italy 49General and Emergency Surgery, University of Perugia, Perugia, Italy 50Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy 51Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Morgagni-Pierantoni Hospital, Forlì, Italy 522nd Department of General and Oncological Surgery, Wroclaw Medical University Hospital, Wrocław, Poland 53Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands 54Head Contilia Center for Esophageal Diseases Elisabeth Hospital Essen, Cooperation Partner of West German Tumor Center, University Medicine Essen, Germany 55Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland 56Federal University of São Paulo, São Paulo, SP, Brazil 57Surgical Oncology Department, Portuguese Oncology Institute of Porto (IPO-Porto), 4200-072 Porto, Portugal 58Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands 59Department of Medical Oncology, University Cancer Center Leipzig, Leipzig University Medical Center, Leipzig, Germany 60IRCCS Istituto Romagnolo per Lo Studio Dei Tumori (IRST) "Dino Amadori", Meldola, Italy 61German Society of Surgery, Berlin, Germany 62Department of Surgical Oncology, UT MD Anderson Cancer Center, Houston, Texas, USA 63Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig AöR, Leipzig, Germany 64Division of Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden; Department of Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden 65School of Medicine and Surgery, University of Verona, 37134, Verona, Italy 66Depertment of Surgery, Ospedale S. Antonio Abate, ASST Valle Olona, Gallarate, Italy 67Digestive Surgery Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy 68Department of Gastrointestinal Surgery, IRCCS-San Raffaele Research Hospital, Milan, Italy 69Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Viale Pieraccini, 6, 50139, Florence, Italy 70Division of Oncology, Department of Oncology and Hematology, University Hospital of Modena, 41121 Modena, Italy 71Digestive Oncology Tumor Center, Hirslanden Medical Center, Zurich, Switzerland 72Department of Gastric Surgery, Shizuoka Cancer Center, Shizuoka, Japan 73Chef do Serviço de Cirurgia Geral da Santa Casa, Diretor Médico da Ingastro, Department of Surgery, Porto Alegre, Brazil 74Institute of Clinical Cancer Research, Krankenhaus Nordwest, UCT-University Cancer Center, Frankfurt, Germany; IKF Klinische Krebsforschung GmbH am Krankenhaus Nordwest, Frankfurt, Germany The original article has been corrected

    Ginette Vagenheim, Pirro Ligorio et la statue de saint Hippolyte à la BibliothèqueApostolique Vaticane

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    International audienceDescribed by Johann Joachim Winckelmann (1717-1768) as the oldest Christian statue known in marble, the portrait of saint Hippolytus located at the entrance of the Vatican Library, bearing a Greek female dress, and restored in its upper part in the mid-sixteenth century, has aroused the interest of scholars from various disciplines; epigraphists have sought to elucidate the date and contentof the three Greek inscriptions engraved on the back and sides of the throne, with its armrests adorned with leonine protomes (ICUR VII, 19934 = EDB 3372); specialists in the history of religions have sought to identify the figure of Hippolytus and the works on the back of the throne. They all start from the first account of this monument by Pirro Ligorio (1512c.-1583), the only author to also provide a drawing of the statue as it is supposedto have been discovered in his time, between the Via Nomentana and the Via leading to Tivoli. As a specialist in Ligorio’s life and works, I in turn retraced the story of the statue of Hippolytus through Ligorio’s writings and drawings, which turned out to be quite different from the vulgata, and which also calls into question the authenticity of the inscriptions
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