2,119 research outputs found
Quality Competition Among Hospitals: The Effects of Perceived Quality and Perceived Expensiveness on Healthcare Consumers
No full textMagnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain.
No full textResearch on the Strategic Marketing Analysis for the Biotech-Beauty Industry: A Case of Company YJ
No full textAt present, the medical aesthetics industry is growing rapidly and increasingly competitive in the market. With Taiwan's medical aesthetics output value exceeding 40 billion, the consumer base ranges from teens to 60s. This research is based on the marketing strategy research of YJ. Biotechnology Company. YJ. Company is a biotech company that has transformed from OEM to self-owned brand. The founder has a very experienced background in the biotechnology industry and factory has been established for many years. Hoping through this research, the self-created brand can be successfully promoted. In addition to providing high-quality products, YJ. Company has been paid more efforts to consumers' perception of product effects and service.
The research methodology is used case studies, five forces analysis, 4P and SWOT analysis as the research framework. The conclusions and recommendations are that YJ. Company is keeping strengthening advertising and sales channels, meanwhile continuing the company\ue2s insistence on product technology and increasing products with multiple types of services, to establish a strong professional management team. It\ue2s firmly believed that once the business model of experiential marketing is strengthened, it can be forwarded to other Southeast Asian countries, even marketing Taiwan\ue2s products to all over the world. YJ. Company strongly believes to establish the own brand internationally, then marketing into the world
Differentiation of ketamine effects on renal nerve activity and renal blood flow in rats
No full textDelayed diagnosis of esophageal perforation following intraoperative transesophageal echocardiography during valvular replacement--- a cae report.
No full textThe F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination.
No full textNaphthazarin and methylnaphthazarin cause vascular dysfunction by impairment of endothelium-derived nitric oxide and increased superoxide anion generation.
No full textIsolation and Identification of Burkholderia stagnalis YJ-2 from the Rhizosphere Soil of Woodsia ilvensis to Explore Its Potential as a Biocontrol Agent Against Plant Fungal Diseases
No full textPlant fungal diseases remain a major threat to global agricultural production, necessitating eco-friendly and sustainable strategies. Conventional chemical fungicides often lead to the development of resistant pathogen strains and cause environmental contamination. Therefore, the development of biocontrol agents is particularly important. In this study, we identified Burkholderia stagnalis YJ-2 from the rhizosphere soil of Woodsia ilvensis as a promising biocontrol strain using 16S rRNA and whole-genome sequencing. This strain demonstrated broad-spectrum antifungal activity against plant fungal pathogens, with its bioactive extracts maintaining high stability across a temperature range of 25–100 °C and pH range of 2–12. We used in vitro assays to further show that the metabolites of B. stagnalis YJ-2 disrupted the hyphal morphology of Valsa mali, resulting in swelling, reduced branching, and increased pigmentation. Fluorescence labeling confirmed that B. stagnalis YJ-2 stably colonized the roots and stems of tomato and wheat plants. Furthermore, various formulations of microbial agents based on B. stagnalis YJ-2 were evaluated for their efficacy against plant pathogens. The seed-coating formulation notably protected tomato seedlings from Alternaria solani infection without affecting germination (p > 0.1), while the wettable powder exhibited significant control effects on early blight in tomatoes, with the preventive treatment showing better efficacy than the therapeutic treatment. Additionally, the B. stagnalis YJ-2 bone glue agent showed a substantial inhibitory effect on apple tree canker. Whole-genome analysis of B. stagnalis YJ-2 revealed a 7,705,355 bp genome (67.68% GC content) with 6858 coding genes and 20 secondary metabolite clusters, including three clusters (YJ-2_GM002015-YJ-2_GM002048, YJ-2_GM0020090-YJ-2_GM002133, and YJ-2_GM06534-YJ-2_GM006569) that are related to the antifungal activity of YJ-2 and are homologous to the biosynthetic gene clusters of known secondary metabolites, such as icosalide, ornibactin, and sinapigladioside. We further knocked out core biosynthetic genes of two secondary metabolic gene clusters and found that only the YJ-2_GM006534-YJ-2_GM006569 gene cluster had a corresponding function in two potential antifungal gene clusters. In contrast to the wild-type strain YJ-2, only deletion of the YJ-2_GM006563 gene reduced the antifungal activity of B. stagnalis YJ-2 by 8.79%. These findings highlight the biocontrol potential of B. stagnalis YJ-2, supporting a theoretical foundation for its development as a biocontrol agent against plant fungal diseases and thereby promoting sustainable agricultural disease management
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