1,722,061 research outputs found
Minireview: Current status of endoscopic duodenal mucosal resurfacing
Full text linkSeveral strategies are being pursued to overcome the alarming pandemics of obesity and type 2 diabetes (T2D). In recent years, duodenal mucosal resurfacing (DMR) has shown its potential to improve glycemic indices. Following animal studies, which demonstrated feasibility and safety, the procedure has been applied in two human studies. The DMR procedure has been considered feasible and safe in humans with a limited occurrence of complications and adverse events. Reductions in glycated haemoglobin, weight, fasting plasma glucose, and alanine transaminase have been proven at different follow-up time-points. The length of the ablation may induce different outcomes, having the patients with long duodenal segment ablated showed greater beneficial effects. The current evidence does not still prove the apparent insulin-sensitizing mechanism explaining the impact of the DMR procedure on hepatic glucose production. However, the initial findings have demonstrated a positive risk-benefit ratio and an effect on the treatment of metabolic diseases, such as T2D. Future studies should clarify the mechanisms underlying the positive effects and durability of the treatment using controlled trial conditions on larger number of patients
Production and purification of monoclonal and polyclonal antibodies against human ferritin, a nonspecific tumor marker.
No full textDetection of tetrodotoxin by high performance liquid chromatography in lined-moon shell and puffer fish.
No full textA modified high-performance liquid chromatography method for analysis of PSP toxins in dinoflagellate, Alexandrium minutum , and shellfish from Taiwan.
No full textTransmission of the paralytic shellfish poisoning toxins, from dinoflagellate to gastropod.
No full textParalytic shellfish poisoning toxins accumulation in purple clam Hiatula rostrata and toxic effect on milkfish Chanos chanos larval fish.
No full textAccumulation and depuration of paralytic shellfish poisoning toxins by purple clam Hiatula rostrata Lighttoot.
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Comparison of supercritical fluid and soxhlet extraction methods for the determination of chlorothalonil from cranberry bog soils
No full textPossible age-associated bias in reporting of clinical features of drug dependence: epidemiological evidence on adolescent-onset marijuana use.
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