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    Observation of Planarian Regeneration by Optical Coherence Tomography with Statistical Tissue Analysis

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      光學同調斷層掃描系統具有非侵入式、無輻射汙染以及成像結果迅速等優勢,成為近代成熟發展之醫學影像系統之一。本文即是利用光學同調斷層掃描系統作為主要的研究工具,並針對具有發展再生醫學研究潛力之渦蟲做為一動物模型來進行研究。為了達到這個目的,實驗內容將比較切割前之渦蟲組織與切割後之渦蟲組織。控制變因為渦蟲之不同位置以及切割後所經過的時間。希望能完整的以光學同調斷層掃描結果描述渦蟲的再生。   研究所使用的分析方法為紋理統計分析。由光學斷層掃描系統所截取之B-Scan影像中選取一個感興趣之位置範圍,並建立其空間灰階相關矩陣。再由該矩陣進行運算得到各項紋理特徵參數,包括對比度、相關性、能量、同質性以及熵。再分別就不同時間、不同位置之各項紋理特徵參數進行比較。   在實驗的分析結果中可明顯的發現,紋理分析特徵參數可以有效的描述渦蟲在光學同調斷層掃描系統所拍攝之B-Scan影像之影像特性。對比度、相關性以及能量在特定範圍間,可以表示該選取位置區域之影像具有較高濃度之高灰階值粒子聚集。而相關性的大小可以評估該高灰階值粒子在各個方向上的排列是否具有高度的方向性。而同質性與亂度可以表示所得之訊號中雜訊對關心區域影像之影響。因此能夠以量化方式描述渦蟲的再生,希望能建立一套量化標準,去評估渦蟲的再生狀況,減少人為判斷之誤差,以提供再生醫學研究一種之輔助判準。  Optical coherence tomography (OCT) is an established medical imaging technique. The key benefit of optical coherence tomography is non-invasive and instant imaging of live tissues without ionizing radiation. This study used OCT to investigate the planarian as a model for regenerative medicine. This experiment compares the tissue of the planarian before cutting and after cutting. Variables are the planarian’s different locations and the time elapsed after cutting. Hoping to completely describe the planarian regeneration with OCT.   The statistical method used for describing tissue is texture features analysis. First, select a region of interest (ROIs) in the B-Scan image by OCT to establish its spatial gray level dependence matrices. Then calculate the texture features properties, including contrast, correlation, energy, homogeneity and entropy. Lastly, compare the different times and locations of the texture properties.   The result showed that texture feature properties can effectively describe the B-Scan images of the planarian by OCT. Contrast, correlation and energy in the specific value can represent the high concentration of high gray level value particles gathering. Furthermore, the scale of correlation can also be assessed high gray level value particles are highly directional arrangement. The homogeneity and entropy can be expressed the impact of noise in the ROIs.   It is possible to quantify the regeneration of planarian, hoping to establish a quantitative criteria to assess the state of regeneration and reduce errors of human judgment, in order to provide an auxiliary method in regenerative medicine studies

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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