159,051 research outputs found
Ptisana ambulans Murdock & C. W. Chen
No full textPtisana ambulans Murdock & C.W. Chen: Solomon Islands, New Georgia, (629), Voucher: C.-W. Chen & T.-C. Hsu SITW00629 (TAIF, TNM, BSIP), GenBank: MW051627, MW051612.Published as part of Shepherd, Lara D., Murdock, Andrew G., Amice, Rémy & Perrie, Leon R., 2023, A synopsis of Ptisana Murdock ferns (Marattiaceae) in New Caledonia based on sequence data and morphology with the recognition of a new vulnerable species, P. soluta (Compton) Murdock & Perrie, comb. nov., stat. nov., pp. 41-59 in Adansonia (3) (3) 45 (3) on page 57, DOI: 10.5252/adansonia2023v45a3, http://zenodo.org/record/766506
Corrigendum to “General reduced vehicle model for simulating truck-bridge pier collisions” [Dev. Built. Environ. 16 (2023) 100233] (Developments in the Built Environment (2023) 16, (S2666165923001151), (10.1016/j.dibe.2023.100233))
No full textThe authors regret there were two errors in the authors' affiliation in the published article. First, the affiliation of the first author (Daogang Ou) should only be the School of Civil Engineering, Hunan University of Science and Technology, Xiangtan, 411201, China. Second, the corresponding author (Lin Chen) should have two affiliations; the first one should be: School of Civil Engineering, Hunan University of Science and Technology, Xiangtan, 411201, China; and the second one should be: Key Laboratory of Building Safety and Energy Efficiency of Ministry of Education, Hunan University, Changsha, 410082, China. The authors would like to apologise for any inconvenience caused
C.-W. Chen, Apparence et représentation en droit positif français
No full textC.-W. Chen, Apparence et représentation en droit positif français. In: Revue internationale de droit comparé. Vol. 53 N°2, Avril-juin 2001. pp. 515-516
C.-W. Chen, Apparence et représentation en droit positif français
No full textC.-W. Chen, Apparence et représentation en droit positif français. In: Revue internationale de droit comparé. Vol. 53 N°2, Avril-juin 2001. pp. 515-516
Overexpression of Cyclin D1 and C-Myc Gene Products in Human Primary Epithelial Ovarian Cancer
No full textCyclin D1 and c-Myc are key participants in the cell-cycle pathway, in which aberrancies have been associated with malignant transformation. To date, data on the relationship of expression of these proteins and histologic subtype of epithelial ovarian cancer are still scarce and discordant. Immunohistochemical analysis was performed on 12 normal ovaries and 47 cases of serous, mucinous, endometrioid, and clear cell ovarian carcinomas. No abnormal expression of cyclin D1 or c-Myc was demonstrated in any of the 12 normal ovarian specimens. However, compared to normal ovarian tissues, overexpression of cyclin D1 and c-Myc was observed in 42.6% (20/47) and 65.9% (31/47) of tumors examined, respectively. There was no significant difference of overexpression of cyclin D1 or c-Myc gene products between these four histologic subtypes of ovarian adenocarcinomas. This study shows that cyclin D1 and c-Myc are frequently overexpressed in epithelial ovarian carcinomas, but they are not correlated with a particular histologic subtype. Although our preliminary results need to be validated in a larger number of tumors, the abnormal expression of cyclin D 1 and c-Myc in epithelial ovarian cancer reaffirms the notion that they are crucial components in the pathway of tumorigenesis and deserve further study
Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation
No full textCellular FLICE-inhibitory protein (c-FLIP) is an inhibitor of caspase-8 and is required for macrophage survival. Recent studies have revealed a selective role of caspase-8 in noncanonical IL-1 beta production that is independent of caspase-1 or inflammasome. Here we demonstrated that c-FLIPL is an unexpected contributor to canonical inflammasome activation for the generation of caspase-1 and active IL-1 beta. Hemizygotic deletion of c-FLIP impaired ATP-and monosodium uric acid (MSU)-induced IL-1 beta production in macrophages primed through Toll-like receptors (TLRs). Decreased IL-1 beta expression was attributed to a reduced activation of caspase-1 in c-FLIP hemizygotic cells. In contrast, the production of TNF-alpha was not affected by downregulation in c-FLIP. c-FLIPL interacted with NLRP3 or procaspase-1. c-FLIP is required for the full NLRP3 inflammasome assembly and NLRP3 mitochondrial localization, and c-FLIP is associated with NLRP3 inflammasome. c-FLIP downregulation also reduced AIM2 inflammasome activation. In contrast, c-FLIP inhibited SMAC mimetic-, FasL-, or Dectin-1-induced IL-1 beta generation that is caspase-8-mediated. Our results demonstrate a prominent role of c-FLIPL in the optimal activation of the NLRP3 and AIM2 inflammasomes, and suggest that c-FLIP could be a valid target for treatment of inflammatory diseases caused by over-activation of inflammasomes
Synthesis of New Fluorene-Indolocarbazole Alternating Copolymers for Light-Emitting Diodes and Field Effect Transistors
No full textEffect of postgrowth hydrogen treatment on defects in GaNP
Full text linkEffect of postgrowth hydrogen treatment on defects and their role in carrier recombination in GaNP alloys is examined by photoluminescence (PL) and optically detected magnetic resonance. We present direct experimental evidence for effective activation of several defects by low-energy subthreshold hydrogen treatment (andlt;= 100 eV H ions). Among them, two defect complexes are identified to contain a Ga interstitial. Possible mechanisms for the H-induced defect activation and creation are discussed. Carrier recombination via these defects is shown to efficiently compete with the near band-edge PL, explaining the observed degraded optical quality of the alloys after the H treatment.Original Publication:Daniel Dagnelund, Xingjun Wang, C W Tu, A Polimeni, M Capizzi, Weimin Chen and Irina Buyanova, Effect of postgrowth hydrogen treatment on defects in GaNP, 2011, APPLIED PHYSICS LETTERS, (98), 14, 141920.http://dx.doi.org/10.1063/1.3576920Copyright: American Institute of Physicshttp://www.aip.org
- …
