5,098 research outputs found
Recommended from our members
A Performance Analysis of Chen Yi’s Chinese Ancient Dances for Bb Clarinet and Piano
Full text linkChen Yi’s use of Chinese traditional art forms adds vivid layers of imagery and narrative to her music. In Chinese Ancient Dances for Bb Clarinet and Piano (2004), inspiration from ancient dances and poetry brings these layers to life. The influence of dance lends a physical and dynamic quality, while poetic elements add depth and meaning. Chen Yi’s incorporation of these traditional forms provides a sense of specificity, making her compositions both accessible and expressive.This dissertation examines how Chen Yi integrates Chinese traditional arts, including poetry, dance and folk music, into her music through a comprehensive study of her work Chinese Ancient Dances for Bb Clarinet and Piano (2004)
EBCT - McGoon Ratio A Reliable and Useful Method to Predict Pulmonary Blood Flow Non-invasively.
No full textCrossed pulmonary arteries: report of two cases with emphasis on three-dimensional helical computed tomographic imaging.
No full textEffects of MAPK inhibitors on cell cycle regulator protein expression in PDGF-BB-treated HASMCs.
No full textCells were treated with 30 μM MAPK inhibitors for 1 h, and then incubated with 30 ng/mL PDGF-BB for 24 h. The expression of (A) Cyclin D1, (B) Cyclin E, (C) p27Kip1, (D) CDK4, (E) CDK2, (F) or p21Cip1 proteins was determined by Western blot analysis. β-actin was processed in parallel as an internal control for protein loading. The histograms show the phosphorylated band/β-actin ratio (A-F). *P†P<0.05 vs. the PDGF-BB-treated cells.</p
Effects of viscolin expression on the phosphorylation of MAPKs and AKT in PDGF-BB-treated HASMCs.
No full textCells were treated with 40 μM viscolin for 24 h and then incubated with or without 30 ng/mL PDGF-BB for 30 min. Phosphorylated (A) JNK, (B) P38, (C) ERK1/2, or (D) AKT levels were determined by Western blot analysis. GAPDH was processed in parallel as an internal control for protein loading. The histograms show the phosphorylated band/GAPDH ratio for (A-D). *P†P<0.05 vs. the PDGF-BB-treated cells.</p
Viscolin reduces the migration and proliferation of PDGF-BB-treated HASMCs.
No full textSerum-starved HASMCs were cultured with PDGF-BB (PDGF) alone or with viscolin (VIS). (A) Cell viability was measured using the MTT assay. (B) Cell death was assessed using the TUNEL assay. Cells treated with 1 mg/mL DNase I were the positive controls (PC). (C) BrdU incorporation was used to determine HASMC proliferation. Some cells were pretreated with 30 μM MAPK inhibitors for 30 min prior to treatment with viscolin or PDGF-BB. Representative photographs are shown in the left panel, and the quantitative data relative to the control value (without any treatment) were shown in the right panel. (D) Cell migration was examined in a wound healing assay. Serum-starved HASMCs were wounded by scratch injury (black lines on Fig). The wound closure area was determined by measuring the wound area/initial wound area. Before wound formation and PDGF-BB and or/ viscolin treatment, some cells were pretreated with an ERK1/2 inhibitor (PD98059; PD), P38 inhibitor (SB203580; SB) or JNK inhibitor (SP600125; SP) for 30 min. Representative inverted phase contrast light microscopy photographs are shown in the left panel and the quantified data are shown in the right panel. In A, C, and D, the data are means±SEM for four independent experiments. *P†P‡P<0.05 vs. the viscolin/PDGF-BB group. The scale bars in B- D = 100 μm.</p
Etälukutapahtuman tehostaminen BB Logisticsilla
Full text linkTämän opinnäytetyön tavoitteena oli osoittaa viivakoodillisten pallettien käsittelyprosessien lukutapahtumien näkökulmasta ilmenevät ongelmat. Työ tehtiin toimeksiantolähtöisenä BB Logisticsin Haminan toimipisteelle. Asetettujen tutkimuskysymysten myötä tekijän piti dokumentoida viivakoodien lukutapahtumaan liittyvät ongelmat ja löytää ratkaisut todettuihin ongelmiin. Työn aihe sai alkunsa syksyllä 2019, kun viivakoodit otettiin ensimmäistä kertaa käyttöön. Tutkimuksen virikkeenä toimi aiheen ajankohtaisuus.
Opinnäytetyö ja teoreettinen viitekehys rakentuivat kvalitatiivista tutkimusmenetelmää käyttäen. Työssä käytettiin kirjallisten lähteiden lisäksi tekijän omia käytännön kokemuksia, verkkosivustoja sekä kirjallisia haastatteluita. Haastatteluiden tarkoituksena oli ensisijaisesti lisätä työssä ilmi tuotujen näkökulmien luotettavuutta. Haastattelut tehtiin suullisesti ja epävirallisesti marraskuussa 2019 työn alkuvaiheessa. Virallinen dokumentointi suoritettiin helmikuussa 2020 kirjallisten haastatteluiden muodossa. Haastattelun kysymykset olivat avoimia kysymyksiä, joihin vastasi kuusi työtoveria. Haastattelujen toteutusta voidaan opinnäytetyön tulosten kannalta pitää erittäin onnistuneena, koska haastattelussa esiin tuoduissa näkökulmissa oli yhtäläisyyksiä tekijän omien näkemysten kanssa.
Tutkimuksen tavoitteet saavutettiin tyydyttävästi. Tavoitteisiin päästiin löytämällä optimaalisin tapa viivakoodilukutapahtuman toteutukseen nykyisessä tilassa ja tarjoamalla ratkaisuja nykyisen etälukutapahtuman tuomiin ongelmiin. Opinnäytetyössä ilmi tulleet ongelmat luokiteltiin aikahäviöiden aiheuttajiksi. Päätös käsittelyprosessien aikana syntyvien aikahäviöiden minimoimisesta on tehty ja liittyy viivakooditarrojen määrän lisäämiseen tuotteessa. Päätös viivakoodien määrän lisäämisestä ajoittuu todennäköisesti vuoden 2020 jälkipuoliskolle. Tämän lisäksi työssä mainittiin RFID:n käyttöönottomahdollisuus, jonka tarkoituksena oli antaa toimeksiantajalle ja asiakkaalle laajempi näkökulma aiheeseen.The objective of this thesis was to pinpoint key issues regarding the current state of remote reading as it is done during the pallet handling processes at BB Logistics Oy’s Hamina office. The set research questions also required the author to document these issues and find possible solutions to them. The topic of this thesis originated during the fall of 2019 when the barcodes were first introduced into the handling processes with a few hindrances. The reaction to handling barcodes was initially flawed, which sparked the topic and its pitching to the author.
This thesis and its theory were structured by using qualitative methods. In addition to using usual sources such as books, own practical experience and many websites, interviews were used to boost reliability of the perspectives that were highlighted in this thesis. Written interviews were conducted towards the end of the study in February 2020; however, the same interviews were conducted orally during the research process in November 2019. The questionnaire included open questions that were answered by 6 different fellow employees. The use of interviews can be considered very successful in terms of results, because the interview’s results concur with the author’s results.
The goals of this thesis were met with satisfying results, this was achieved by locating the most optimal way of reading barcodes in their current state and by suggesting solutions to obstacles faced during the remote reading. In the thesis it was discovered that hindrances cause time losses. A step towards implementing a solution to reduce time losses during handling processes was suggested. A decision to increase the number of barcodes has been made and it is likely to take place in the second half of 2020. The aim of this is to improve the general quality of work. Additionally, the possibility of implementing RFID technology was mentioned briefly – this was mainly done to raise some follow-up questions and give the commissioner and the customer broader perspectives on remote reading
PDGF-BB-stimulated-VSMC showed increased proliferation and migration as well as ROS.
No full textVSMC from WT mice in basal conditions displayed low concentration of ROS production, PDGF-BB (20 μg/l) treatment significantly elevated ROS level (a). Proliferation and migration of VSMC showed significant increase in response to PDGF-BB compared with con group (b and c). NAC (10mmol/l) significantly reduced the intracellular ROS production and VSMC proliferation and migration induced by PDGF-BB. (*Pvs. con; #Pvs. PDGF). Con, wild-type VSMCs in basal conditions; PDGF, PDGF-BB, platelet derived growth factor-BB; NAC, N-acetylcysteine; ROS, reactive oxygen species.</p
PPARγ inhibited PDGF-BB-induced VSMC proliferation, migration and oxidative stress.
No full textCultured VSMCs were incubated with RSG (10μmol/L) for different times (0, 1, 6, 12 or 24 h). PPARγ expression increased in time-dependent manner, with an obvious effect at 6 h and the peak at 12 h that sustained after 24 h (a). (*Pvs. 0 h). RSG treatment for 12 h significantly counteracted ROS generation induced by PDGF-BB in VSMCs, while PPARγ inhibitor GW9662 diminished the effect of RSG (b). VSMCs treated with RSG showed reduced proliferation and PCNA expression, VSMC migration and MMP9 expression in response to PDGF-BB, which was reversed by GW9662 (c and d). (*Pvs. con; #Pvs. PDGF; ΔPvs. PDGF+RSG). Con, wild-type VSMCs in basal conditions; PDGF, PDGF-BB, platelet derived growth factor-BB; ROS, reactive oxygen species; RSG, rosiglitazone; GW9662, PPARγ inhibitor; PCNA, proliferating cell nuclear antigen; MMP9, matrix metalloproteinase 9.</p
Effects of ERK, P38, and JNK-specific siRNA on cell cycle regulator protein expression in PDGF-BB-treated HASMCs.
No full textThe expression of the (A) Cyclin D1, (B) CDK4, (C) Cyclin E, (D) CDK2, and (E) p21Cip1 proteins was determined by Western blot analysis after ERK, P38, and JNK silencing, viscolin and PDGF-BB treatment. (F) ERK, P38, and JNK-specific siRNAs reduced the total levels of the ERK, P38, and JNK proteins compared with the non-treated cells. The values are the means±SEM. *P†P<0.05 vs. the PDGF-BB-treated cells.</p
- …
