1,720,986 research outputs found
The Impact of Social Networks and Human Capital on Social Mobility: A Study of the Yunlin County Association of New Taipei City
No full text城鄉移民是工業化及都市化過程中的顯著現象，國內過去關於此方面的研究，多集中在探討造成鄉村人口往城市遷移的原因，以及大量鄉村人口進入城市後的影響，但對於鄉村人口遷入城市後，是否發生社會流動，以及何以出現不同的社會流動的探討，卻相對稀少。
根據政府的人口遷移資料，雲林縣是我國人口外移最多的縣市之一，該縣的外流人口主要移至新北市，初估約有40萬的雲林人旅居新北市。許多先後從雲林縣北上的人成立新北市雲林同鄉會，形成凝聚鄉親向心力的重要組織。然而，新北市雲林同鄉會的會員們，在歷經多年的遷移生活後，彼此的職業變遷、社會地位出現不同的結果。為何來自相同故鄉的人，後來的社會流動卻彼此不同？本研究將驗證社會網絡、人力資本是否為影響其社會流動的關鍵因素。根據研究結果，發現「遷移後建構的社會網絡所接觸的社會資源」及「遷移時的受教育年數」均對「主觀的社會流動」有顯著的正向影響，顯示社會網絡及人力資本對促進社會流動有正向的效用。The rural to urban migration is an apparent phenomenon in the process of industrialization and urbanization. According to the past domestic research, most people are concerned about the reason and the influence of migration. However, after the migration, there is little discussion about whether the migration did happen, or what kind of migration it brings.
According to the Taiwan government''s internal migration data, Yunlin County is one of the regions with the largest emigration. About 400,000 Yunlin County''s residents moved to new Taipei county. The people from the Yunlin county organized the Yunlin Association of New Taipei City. This study focused on these Yunlin Association members. Why the group of people from the same hometown are differ within the later social mobility. This study is try to verify either the social network or the human capital is the main factor behind it
Specific binding force measurement using microfluidic system
No full text本論文以開發心臟病量測晶片為背景，量測專一性結合之蛋白質鍵結力。臨床上對於急性冠心症(acute coronary syndrome, ACS)的診斷為症狀評估、心電圖判斷以及心臟酵素濃度的檢測。為實現心臟病患之定點照護系統，本論文所屬計畫致力於開發一生物感測晶片，透過適體(Aptamer)捕捉血液中心臟酵素(Cardiac troponin I)以檢測血液所含酵素的濃度，由於本計畫所開發之生物晶片與微流道結合，透過真空所造成的壓差或毛細力將血液輸送至檢測區域，由於流體所產生的剪力有可能破壞蛋白質的專一性結合，因此本論文致力於量測此種專一性結合之鍵結力，以開發高精確度之簡易量測系統為目標。量測蛋白質間鍵結力之方法已有許多文獻 提出，然而多以原子力顯微鏡(Atomic force microscope)為主要量測方法，以此方法量測，需昂貴的量測儀器與精確控制的量測環境，因此本論文開發一微流體系統間接量測一級抗體與二級抗體之間專一性結合之鍵結力。在本論文中，首先將一級抗體(Rabbit IgG)共價接合於含有羧基(-COOH)的微球體上備用，接著將微流道之基板以氣象沉積之方式，沉積一層高分子層，此高分子層含有NHS-ester官能基，透過此官能基，二級抗體(Anti-rabbit IgG)共價接合於上，當含有一級抗體之微球體通入流到中，微球體上之一級抗體將被流道底部之二級抗體所捕捉而停留於流道中，接著通入緩衝液並逐漸加大流量，當流體所產生之剪力足以破壞鍵結時，微球體將被沖走。此外，利用螢光標記蛋白，單一微球體上所含蛋白質數量可透過螢光強度量化，透過上述實驗並佐以模型計算，一級抗體與二級抗體之間的鍵結力將能夠以計算之方式得知。在量測結果中，我們量測出此對抗體間的鍵結力約為118 pN，此結果與文獻所測出的Human IgG與Anti-human IgG相較之下較大，但已經非常接近。本論文所量測之結果，為凡德瓦力、靜電力與鍵結力的總和，若能以理論剪去靜電力與凡德瓦力的影響，單純由鍵結所提供之鍵結力即可得知。We measured the specific binding force between proteins with the background of the development of heart disease detection biochips. In clinical, it is pathogonostic to have acute coronary syndrome (ACS) of three items that are clinical symptoms, electrocardiography (ECG) diagnosis and cardiac enzymes. To achieve the goal of constructing a point-of-care system for ACS patients, this thesis is dedicated to the development of biological sensing chip. Specifically, aptamers capture the heart blood enzyme (Cardiac troponin I) in order to detect the concentration of the enzyme contained in blood. Since the biochip was combined with the microfluidic channel, the blood was delivered into the sensing area through pressure difference by vacuum or the capillary force. The shear force generated by fluid could break the binding between proteins, so we are committed to measuring the binding force between specific bindings and developing a system with high accuracy to investigate different kinds of protein-protein interactions. The method of measuring the interaction force between proteins had been revealed by many literatures. However, most of them used atomic force microscope (AFM) to measure the force. This method of measurement need well controlled environment. Alternatively, we developed a microfluidic system to measure the binding force between primary antibody and secondary antibody indirectly. In our research, the primary antibody (Rabbit IgG) was covalently bonded to carboxylated (-COOH) microbeads. The substrate of the microchannel was deposited with a film of polymer containing NHS-ester functional group by chemical vapor deposition, and the secondary antibodies (Anti-rabbit IgG) can be covalently bonded on the substrate through these functional groups. The microbeads conjugated with the primary antibodies were injected into the microchannel and captured by the secondary antibodies on the substrate. Then the buffer was injected into the microchannel with gradually increased flow rate. When the shear force was large enough to break the bonds, the microbeads will be washed away. In addition, we quantified the numbers of proteins on one bead with the use of fluorescent labeled protein by fluorescence intensity measurement. With the above experiment and model calculations, the binding force between the primary antibody and the secondary antibody can be calculated. In the measurement results, the binding force between the antibodies was 118 pN. Though the result is greater than the binding force between human IgG and anti-human IgG measured from other literatures, it was still very close. The measured interaction force is attributed to the bond, van der Waals force and electrostatic force. If the van der Walls force and electrostatic force can be eliminated by calculation, the force only contributed by the bond can be investigated
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
- …
