180 research outputs found
Data on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cells
No full textAbstractThe data included in this article are associated with the article entitled “DNA-damage-induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion” (J.Y. Im, S.H. Yoon, B.K. Kim, H.S. Ban, K.J. Won, K.S. Chung, K.E. Jung, M. Won) [1]. Quantitative RT-PCR data revealed that genetic or pharmacological inhibition of extracellular signal-regulated kinase 5 (ERK5) suppresses DDIAS transcription in response to epidermal growth factor (EGF) in Hela cells. p300 did not interact with myocyte enhancer factor 2B (MEF2B), a downstream target of ERK5 and affect transcription of DDIAS. Moreover, DDIAS transcription is activated by ERK5/MEF2B signaling on EGF exposure in the non-small cell lung cancer cells (NSCLC) NCI-H1703 and NCI-H1299. DDIAS knockdown suppresses lung cancer cell invasion by decreasing β-catenin protein level on EGF exposure
Physical dance performance: An investigation into the development of a performance technique based on the integration of certain Korean dance technique and contemporary Western styles of dance and physical theatre
No full textThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 04/10/2001.This development of a performer practice that integrates elements of traditional Korean dance technique and Western forms of physical theatre and contemporary dance is based on an approach to internal understanding and external execution. Central to the work is the concept of body energy, or Ki. This ancient Eastern term is translated into a contemporary practice that enables a performer to engage mental and physical training. Breath and the use of breath in performing are the principal means of achieving this level of engagement
Cloning and characterization of plastid ribosomal protein S16 gene from potato (Solanum tuberosum L. cv Desiree)
No full textThe plastid ribosomal protein s16 (rps16) gene was cloned from potato (Solanum tuberosum L. ssp. tuberosum cv D?sir?e) by PCR amplification to obtain a new homologous recombination site of plastid transformation. The potato rps16 genomic clone was 1627 bp in size and the coding region was interrupted by an 859 bp intron. Exon I was 40 bp, encoding 13 amino acids and exon II was 227 bp, encoding a 76 amino acid polypeptide. The nucleotide sequence of the rps16 gene from the "D?sir?e" potato shared perfect identity with the sequence from the "Superior" potato in the coding region. Three nucleotide substitutions, two nucleotide insertions, and one nucleotide deletion were found between the intron sequence of both "D?sir?e" and "Superior" cultivars. The amino acid sequence of the potato rps16 gene showed a high level of identity with rice, maize, tobacco, and mustard (84-94%) and a relatively low level compared with Bacillus stearothermophilus and E. coli (27-28%). Expression of the rps16 gene was strong in chloroplasts and transcripts were detectable in amylopasts, suggesting that the rps16 gene is active in nonphotosynthetic plastids as well as in photosynthetic plastids. These results indicate that the potato rps16 gene can be used as a new homologous recombination site of plastid transformation for potato cultivars.open
Effect of pre-annealing on physical and electrical properties of SrBi2Ta2O9 thin films prepared by chemical solution deposition
No full textEtch characteristics of iridium in chlorine-containing and fluorine-containing gas plasmas
No full text
Reactive ion etching of Pb(Zr[sub x]Ti[sub 1−x])O[sub 3] thin films in an inductively coupled plasma
No full textWhat caused the extraordinarily hot 2018 summer in Korea?
No full textIn 2018, heatwaves (HWs), which are defined as period of abnormally hot weather with the daily maximum temperature (T_Max) exceeding its 95th percentile threshold for at least three consecutive days, were prevalent during June to August, and temperature records were broken in many countries over East Asia (EA) including China (CH), Japan (JP), and the Korean Peninsula (KP). In particular, extreme HWs through July to August lasted for the longest duration with 21.3 days with T_Max reaching 36.9°C. The highest T_Max, recorded since 1907, exceeded to 41°C in Hongcheon, located east of Seoul in the KP. Here, we examine the factors that influenced the 2018 HW, and how these relate to the 1994 HW, which was second longest HW recorded in the KP. The results show that abnormally strong and northwestward extended anticyclone features observed in July 2018 lasted as a persistent North Pacific anticyclone anomaly until August 2018 centered at the northern KP. These anticyclone features subsequently formed as a modon-like blocking with a cyclonic anomaly in the East China Sea. Meanwhile, in August 1994, the North Pacific High (NPH) extended to eastern EA, which broked the meridional dipole structure and HWs do not persist. The NPH, which persisted till August 2018, was accompanied by a sinking motion, suppression of precipitation, anomalous maximum temperature, weakening of the westerly jet stream, and increased insolation due to clear sky. We find that the prolonged and northwestward-shifted NPH including the KP drove the extraordinarily hot 2018 summer in Korea. In addition, low precipitation and massive evapotranspiration with the persistent insolation in July 2018 influenced the dry condition at the surface. We suggest that the predictions for the location and duration of the NPH associated with the HWs are required to reduce heat-related mortality and the impact on agriculture due to excessive evapotranspiration.©The Author(s) 2020.11sciescopu
A Validation Study of the Korean Version of SPAN
No full textPurpose: The SPAN, which is acronym standing for its four components: Startle, Physiological arousal, Anger, and Numbness, is a short post-traumatic stress disorder (PTSD) screening scale. This study sought to develop and validate a Korean version of the SPAN (SPAN-K). Materials and Methods: Ninety-three PTSD patients (PTSD group), 73 patients with non-psychotic psychiatric disorders (psychiatric control group), and 88 healthy participants (normal control group) were recruited for this study. Participants completed a variety of psychiatric assessments including the SPAN-K, the Davidson Trauma Scale (DTS), the Clinician-Administered PTSD Scale (CAPS), and the State-Trait Anxiety Inventory (STAI). Results: Cronbach's alpha and test-retest reliability values for the SPAN-K were both 0.80. Mean SPAN-K scores were 10.06 for the PTSD group, 4.94 for the psychiatric control group, and 1.42 for the normal control group. With respect to concurrent validity, correlation coefficients were 0.87 for SPAN-K vs. CAPS total scores (p<0.001) and 0.86 for SPAN-K vs. DTS scores (p<0.001). Additionally, correlation coefficients were 0.31 and 0.42 for SPAN-K vs. STAI-S and STAI-T, respectively. Receiver operating characteristic analysis of SPAN-K showed good diagnostic accuracy with an area under the curve (AUC) of 0.87. The SPAN-K showed the highest efficiency at a cutoff score of 7, with a sensitivity of 0.83, a specificity of 0.81, positive predictive value (PPV) of 0.88, and negative predictive value (NPV) of 0.73. Conclusion: These results suggest that the SPAN-K had good psychometric properties and may be a useful instrument for rapid screening of PTSD patients.This study was supported by a grant of the Korean Academy of Anxiety Disorders, Korean Neuropsychiatric Association, and Korean Research Foundation (2006-2005152), Republic of Korea
- …
