1,721,467 research outputs found
The oscillatory transcranial electric stimulation and the amplitude-modulated frequency dictate the quantitative features of phosphenes
Che-Yi Hsu, Tzu-Ling Liu, Chi-Hung Juan. The oscillatory transcranial electric stimulation and the amplitude-modulated frequency dictate the quantitative features of phosphene
The oscillatory transcranial electric stimulation and the amplitude-modulated frequency dictate the quantitative features of phosphenes
Che-Yi Hsu, Tzu-Ling Liu, Chi-Hung Juan. The oscillatory transcranial electric stimulation and the amplitude-modulated frequency dictate the quantitative features of phosphene
Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and upregulates the expression of the acyl CoA oxidase gene in H4IIEC3 hepatoma cells
[[abstract]]Peroxisome proliferator-activated receptor (PPAR) is a ligand-dependent transcription factor that regulates the expression of genes involved in lipid metabolism and transport. Ligands/activators of PPAR, like fibrate-type drugs, may have hypolipidemic effects. To identify food that contains activators of PPAR, a transactivation assay employing a clone of CHO-K1 cells stably transfected with a (UAS)4-tk-alkaline phosphatase reporter and a chimeric receptor of Gal4-rPPAR LBD was used to screen ethyl acetate (EA) extracts of a large variety of food materials. It was found that the EA extract of bitter gourd(Momordica charantia), a common oriental vegetable, activated PPAR to an extent that was equivalent to or even higher than 10 ?M Wy-14643, a known ligand of PPAR. This extract also activated PPAR to a significant extent which was comparable to 0.5 ?M BRL-49653. The activity toward PPAR was mainly in the soluble fraction of the organic solvent. The EA extract prepared from the whole fruit showed significantly higher activity than that from seeds or flesh alone. The bitter gourd EA extract was then incorporated into the medium for treatment of a peroxisome proliferator-responsive murine hepatoma cell line, H4IIEC3, for 72 h. Treated cells showed significantly higher activity of acyl CoA oxidase and higher expressions of mRNA of this enzyme and fatty acid-binding protein, indicating that the bitter gourd EA extract was able to act on a natural PPAR signaling pathway in this cell line. It is thus worth further investigating the PPAR-associated health benefits of bitter gourd
Bitter Gourd Extract Up-regulates mRNA expression of PPARα.PPARα and Some of their Target Genes in Mice
In Vitro Activation of Peroxisome Proliferator Activated Receptor α by Some Extracts from Food Materials
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Coaxial Double Cubic Lattice Constellation for Stokes Vector Direct-Detection Receiver
We propose a new 16-ary modulation format for Stokes vector direct-detection receiver. This format incurs < 0.7-dB receiver sensitivity penalty with respect to the optimum 16-ary constellation, but the transmitter complexity is reduced significantly
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