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Asociación entre el asma y la gravedad de COVID-19 en pacientes pediátricos hospitalizados en el Hospital Nacional Edgardo Rebagliati Martins
Get PDFEl asma es una enfermedad con una gran carga de morbilidad en pacientes pediátricos y ha sido vinculada con una mayor gravedad de COVID-19. Sin embargo, la evidencia es aún escasa y existe variabilidad en los resultados. El objetivo del estudio fue evaluar la asociación entre el asma y la gravedad por COVID-19 en pacientes pediátricos hospitalizados por COVID-19 en el Hospital Nacional Edgardo Rebagliati Martins. Estudio de cohorte retrospectivo que incluyó pacientes pediátricos hospitalizados en el Hospital Nacional Edgardo Rebagliati Martins. La información sobre las características demográficas, laboratoriales y clínicas se extrajeron de los registros médicos electrónicos. Para evaluar la asociación entre asma y gravedad por COVID-19 se estimaron razones de riesgo crudos (RR) y ajustados (aRR) por los potenciales confusores a través de los modelos lineales generalizados. Se incluyeron 233 pacientes de los cuales el 51.1% (n=119/233) eran varones y con una mediana de la edad de 9 años (rango intercuartil 7 a 11). Los síntomas más frecuentes fueron los respiratorios seguidos de los gastroenterológicos. Las comorbilidades más frecuentes fueron las neurológicas y la obesidad. El 10.3% (n=24/233) (intervalo de confianza (IC) 95%: 6.7% a 14.9%) de los pacientes tenían asma. En el análisis bivariado, el asma se asoció con el ingreso a la unidad de cuidados intensivos (p=0.002) y a la necesidad de ventilación mecánica invasiva (p=0.004). En los análisis múltiples, los pacientes con asma (aRR: 2.24, IC95%: 1.63 a 3.09), la obesidad (aRR: 1.72, IC95%: 1.18 a 2.50), comorbilidades cardiológicas congénitas (aRR: 3.19, IC95%: 1.88 a 5.41) y tener dos o más comorbilidades (aRR: 1.70, IC95%: 1.23 a 2.35) se asociaron con mayor riesgo de gravedad de la COVID-19. Por lo tanto, en la población pediátrica hospitalizada por COVID-19, el asma, la obesidad, las comorbilidades cardiológicas congénitas y tener dos o más comorbilidades se asoció con mayor gravedad de la COVID-19.Asthma is a disease with a high disease burden in pediatric patients and has been linked to increased severity of COVID-19. However, the evidence is still scarce and there is variability in the results. The objective of the study was to evaluate the association between asthma and COVID-19 severity in pediatric patients hospitalized for COVID-19 at the Edgardo Rebagliati Martins National Hospital. Retrospective cohort study that included pediatric patients hospitalized at the Edgardo Rebagliati Martins National Hospital. Information on demographic, laboratory, and clinical characteristics were extracted from electronic medical records. To assess the association between asthma and COVID-19 severity, crude (RR) and adjusted (aRR) risk ratios were estimated for potential confounders using generalized linear models. 233 patients were included, of whom 51.1% (n=119/233) were male and with a median age of 9 years (interquartile range 7 to 11). The most frequent symptoms were respiratory followed by gastroenterological. The most frequent comorbidities were neurological and obesity. 10.3% (n=24/233) (95% confidence interval (CI) 6.7% to 14.9%) of patients had asthma. In bivariate analysis, asthma was associated with intensive care unit admission (p=0.002) and the need for invasive mechanical ventilation (p=0.004). In multiple analyses, patients with asthma (aRR: 2.24, 95%CI: 1.63 to 3.09), obesity (aRR: 1.72, 95%CI: 1.18 to 2.50), congenital cardiologic comorbidities (aRR: 3.19, 95%CI: 1.88 to 5.41) and having two or more comorbidities (aRR: 1.70, 95% CI: 1.23 to 2.35) were associated with increased risk of COVID-19 severity. Therefore, in the pediatric population hospitalized for COVID-19, asthma, obesity, congenital cardiologic comorbidities, and having two or more comorbidities were associated with greater severity of COVID-19
Asociación entre el asma y la gravedad de COVID-19 en pacientes pediátricos hospitalizados en el Hospital Nacional Edgardo Rebagliati Martins
Get PDFEl asma es una enfermedad con una gran carga de morbilidad en pacientes pediátricos y ha sido vinculada con una mayor gravedad de COVID-19. Sin embargo, la evidencia es aún escasa y existe variabilidad en los resultados. El objetivo del estudio fue evaluar la asociación entre el asma y la gravedad por COVID-19 en pacientes pediátricos hospitalizados por COVID-19 en el Hospital Nacional Edgardo Rebagliati Martins. Estudio de cohorte retrospectivo que incluyó pacientes pediátricos hospitalizados en el Hospital Nacional Edgardo Rebagliati Martins. La información sobre las características demográficas, laboratoriales y clínicas se extrajeron de los registros médicos electrónicos. Para evaluar la asociación entre asma y gravedad por COVID-19 se estimaron razones de riesgo crudos (RR) y ajustados (aRR) por los potenciales confusores a través de los modelos lineales generalizados. Se incluyeron 233 pacientes de los cuales el 51.1% (n=119/233) eran varones y con una mediana de la edad de 9 años (rango intercuartil 7 a 11). Los síntomas más frecuentes fueron los respiratorios seguidos de los gastroenterológicos. Las comorbilidades más frecuentes fueron las neurológicas y la obesidad. El 10.3% (n=24/233) (intervalo de confianza (IC) 95%: 6.7% a 14.9%) de los pacientes tenían asma. En el análisis bivariado, el asma se asoció con el ingreso a la unidad de cuidados intensivos (p=0.002) y a la necesidad de ventilación mecánica invasiva (p=0.004). En los análisis múltiples, los pacientes con asma (aRR: 2.24, IC95%: 1.63 a 3.09), la obesidad (aRR: 1.72, IC95%: 1.18 a 2.50), comorbilidades cardiológicas congénitas (aRR: 3.19, IC95%: 1.88 a 5.41) y tener dos o más comorbilidades (aRR: 1.70, IC95%: 1.23 a 2.35) se asociaron con mayor riesgo de gravedad de la COVID-19. Por lo tanto, en la población pediátrica hospitalizada por COVID-19, el asma, la obesidad, las comorbilidades cardiológicas congénitas y tener dos o más comorbilidades se asoció con mayor gravedad de la COVID-19.Asthma is a disease with a high disease burden in pediatric patients and has been linked to increased severity of COVID-19. However, the evidence is still scarce and there is variability in the results. The objective of the study was to evaluate the association between asthma and COVID-19 severity in pediatric patients hospitalized for COVID-19 at the Edgardo Rebagliati Martins National Hospital. Retrospective cohort study that included pediatric patients hospitalized at the Edgardo Rebagliati Martins National Hospital. Information on demographic, laboratory, and clinical characteristics were extracted from electronic medical records. To assess the association between asthma and COVID-19 severity, crude (RR) and adjusted (aRR) risk ratios were estimated for potential confounders using generalized linear models. 233 patients were included, of whom 51.1% (n=119/233) were male and with a median age of 9 years (interquartile range 7 to 11). The most frequent symptoms were respiratory followed by gastroenterological. The most frequent comorbidities were neurological and obesity. 10.3% (n=24/233) (95% confidence interval (CI) 6.7% to 14.9%) of patients had asthma. In bivariate analysis, asthma was associated with intensive care unit admission (p=0.002) and the need for invasive mechanical ventilation (p=0.004). In multiple analyses, patients with asthma (aRR: 2.24, 95%CI: 1.63 to 3.09), obesity (aRR: 1.72, 95%CI: 1.18 to 2.50), congenital cardiologic comorbidities (aRR: 3.19, 95%CI: 1.88 to 5.41) and having two or more comorbidities (aRR: 1.70, 95% CI: 1.23 to 2.35) were associated with increased risk of COVID-19 severity. Therefore, in the pediatric population hospitalized for COVID-19, asthma, obesity, congenital cardiologic comorbidities, and having two or more comorbidities were associated with greater severity of COVID-19
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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