1,720,955 research outputs found
A permeability-switchable polypyrrole nano-valve array for reusable drug delivery systems
No full text本論文利用多孔性電致動高分子聚吡咯(polypyrrole)做出可利用其材料本身之氧化還原來控制材料的透水性，利用此材料特性可以做出可重覆使用之奈米閥門陣列，聚吡咯可在內含鈉離子之溶液中驅動，包含人體體液。同時此奈米閥門陣列也提供了混合藥物的供應，此外該微送藥系統反應時間短(<1s)，並且具有極低功耗。
在本文章中，我們在氧化鋁薄膜(anodic aluminum oxide)上先鍍上一層金，接著再用電化學反應將聚吡咯聚合在金之上，最後再將鍍完聚吡咯後的薄膜合軟性電路板整合成微送藥系統。
此奈米閥門送藥系統可應用於植入式微送藥系統或生物感測晶片，因聚吡咯材料有相當高的重覆使用性，加上其應變量大，僅需極低的驅動能量(電壓<1 V，電流~10-5 A)，可在室溫下操作，易進行微製程，亦可在溶液中驅動。The electro-active polymer polypyrrole has small power consumption in aqueous working media. Due to its stability, incorruptibility and micromachining compatibility, polypyrrole plays an important role in developing micro/nano-actuators for biological in vivo applications. This thesis presents a flexible and reusable polypyrrole nano-valve array for controllable drug delivery. This system works in aqueous media even in the body fluid. It also provides mixable drugs. The system has extremely low power consumption and short response time. The nano-valves are formed by depositing polypyrrole by a novel method on an anodic aluminum oxide (AAO) film which has uniform nano-holes. This method ensures the uniformlity of the polypyrrole and the integrity of the AAO film. After the deposition, the nano-valves are integrated with a flexible print circuit. The valves are actuated through the oxidation and reduction of the polypyrrole. The reduction state of the polypyrrole makes sodium ions entering the polypyrrole and hence swells the polypyrrole. During the swelling situation, the polypyrrole becomes permeable. Hence the valve is opened. Conversely, the polypyrrole is compressed and becomes impermeable in the oxidation state. By controlling the open/close time with constant voltage, the diffusive characteristics of the nano-valves can be easily changed
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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