83,912 research outputs found
Coulter, Chan L., July 23, 1996 [Interview]
No full textProfessor of Philosophy Chan L. Coulter was interviewed on June 17, 1996, by Michael Birkner and David Hedrick about his career at Gettysburg College, including memorable colleagues, classes, and controversies.Dunn, Seymour B.; Glatfelter, Charles H.; Hanson, C. Arnold; Crapster, Basil L.; Barnes, Robert D.; Baskerville, Edward J.; Mara, Richard T.; Qually, Ingolf; Bugbee, Bruce W.; Richardson, Norman E.; Bolich, Harry F.; Arms, Richard A.; Mason, Francis C.; Taylor, Kathrine Kressmann; Schmidt, Emile O.; Glassick, Charles E.; Potts, David B.Willard S. Paul Years; Carl Arnold Hanson Years; Charles E. Glassick Years; Gordon A. Haaland Year
Coulter, Chan L., June 17, 1996 [Interview]
No full textProfessor of Philosophy Chan L. Coulter was interviewed on June 17, 1996, by Michael Birkner and David Hedrick about his childhood, his education, his time as an ROTC instructor, and aspects of his career at Gettysburg College.Clouse, Danner; Richardson, Norman E.; Schubart, W. Richard; Portmess, Lisa; Glassick, Charles E.; Holder, Leonard I.; Potts, David B.; Paul, Willard S.; Hanson, C. ArnoldWillard S. Paul Years; Carl Arnold Hanson Years; Charles E. Glassick Years; Gordon A. Haaland Year
Chan An Ancient Maya Farming Community
No full textThe farming community of Chan thrived for over twenty centuries, surpassing the longevity of many larger Maya urban centers. Between 800 BC and 1200 AD it was a major food production center, and this collection of essays reveals the important role played by Maya farmers in the development of ancient Maya society. Chan offers a synthesis of compelling and groundbreaking discoveries gathered over ten years of research at this one archaeological site in Belize. The contributors develop three central themes, which structure the book. They examine how sustainable farming practices maintained the surrounding forest, allowing the community to exist for two millennia. They trace the origins of elite Maya state religion to the complex religious belief system developed in small communities such as Chan. Finally, they describe how the group-focused political strategies employed by local leaders differed from the highly hierarchical strategies of the Classic Maya kings in their large cities. In breadth, methodology, and findings, this volume scales new heights in the study of Maya society and culture.Cover -- Title -- Copyright -- Contents -- List of Figures -- List of Tables -- Foreword -- Acknowledgments -- 1. Introducing the Chan Site: Farmers in Complex Societies -- Part 1. Time, Space, and Landscapes -- 2. A Changing Cultural Landscape: Settlement Survey and GIS at Chan -- 3. Ceramics and Chronology at Chan -- 4. Agricultural Practices at Chan: Farming and Political Economy in an Ancient Maya Community -- 5. Agroforestry and Agricultural Production of the Ancient Maya at Chan -- Part 2. Life in a Farming Community Center -- 6. Ritual in a Farming Community -- 7. Nonroyal Governance at Chan's Community Center -- 8. "Empty" Spaces and Public Places: A Microscopic View of Chan's Late Classic West Plaza -- Part 3. Diversity across the Chan Community -- 9. Recognizing Difference in Small-Scale Settings: An Examination of Social Identity Formation at the Northeast Group, Chan -- 10. Organization of Chert Tool Economy during the Late and Terminal Classic Periods at Chan: Preliminary Thoughts Based upon Debitage Analyses -- 11. Limestone Quarrying and Household Organization at Chan -- Part 4. Bodies, Material Culture, and Meaning -- 12. The Chan Community: A Bioarchaeological Perspective -- 13. Creating Community with Shell -- 14. Obsidian Acquisition, Trade, and Regional Interaction at Chan -- 15. Contextualizing Ritual Behavior: Caches, Burials, and Problematical Deposits from Chan's Community Center -- Part 5. Conclusion -- 16. Learning from an Ancient Maya Farming Community -- References -- List of Contributors -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- V -- W -- X -- YThe farming community of Chan thrived for over twenty centuries, surpassing the longevity of many larger Maya urban centers. Between 800 BC and 1200 AD it was a major food production center, and this collection of essays reveals the important role played by Maya farmers in the development of ancient Maya society. Chan offers a synthesis of compelling and groundbreaking discoveries gathered over ten years of research at this one archaeological site in Belize. The contributors develop three central themes, which structure the book. They examine how sustainable farming practices maintained the surrounding forest, allowing the community to exist for two millennia. They trace the origins of elite Maya state religion to the complex religious belief system developed in small communities such as Chan. Finally, they describe how the group-focused political strategies employed by local leaders differed from the highly hierarchical strategies of the Classic Maya kings in their large cities. In breadth, methodology, and findings, this volume scales new heights in the study of Maya society and culture.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Forcipomyia (Euprojoannisia) dolichopodida Chan and Linley
No full textForcipomyia (Euprojoannisia) dolichopodida Chan and Linley Forcipomyia (Euprojoannisia) dolichopodida Chan and Linley, 1989: 253 (Florida); Borkent and Grogan 2009: 7 (in Nearctic catalog; distribution). Discussion. Chan and Linley (1989) described this species from the same locality as Atrichopogon (A.) wirthi in St. Lucie Co, Florida (see above). We provide an additional record from this county. New records. St. Lucie Co. (no locality given), 1 Oct. 1986, R. L. Escher, 1 female (FSCA).Published as part of William L. Grogan, Jr., Hribar, Lawrence J., Murphree, C. Steven & Cilek, James E., 2010, New records of biting and predaceous midges from Florida, including species new to the fauna of the United States (Diptera: Ceratopogonidae), pp. 1-59 in Insecta Mundi 2010 (147) on page 10, DOI: 10.5281/zenodo.535290
Atrichopogon (Atrichopogon) wirthi Chan and Linley
No full textAtrichopogon (Atrichopogon) wirthi Chan and Linley Atrichopogon wirthi Chan and Linley, 1988: 189 (Florida). Atrichopogon (Atrichopogon) wirthi: Borkent and Grogan 2009: 5 (in Nearctic catalog). Discussion. Soon after Wilkening et al. (1985) summarized the biting midge fauna of Florida, Chan and Linley (1988) described this species from all stages that were collected and/or reared from leaves of water lettuce, Pistia stratiodes Linnaeus, in St. Lucie Co. during 1987. We examined five adult females and two males in the FSCA that Wirth mounted on slides that were reared from the type locality by Chan. We also provide data on additional specimens that were collected on water lettuce and reared to adults by R. L. Escher during 1987 that were sent to WLG to identify. We are not certain if these specimens originated from the type locality, regardless, this species is still only known from St. Lucie Co. New records. St. Lucie Co., Ft. Pierce, 27 May 1987, R. L. Escher, ex. Pistia stratiodes, 3 females, 2 males (WLGC; FLKC).Published as part of William L. Grogan, Jr., Hribar, Lawrence J., Murphree, C. Steven & Cilek, James E., 2010, New records of biting and predaceous midges from Florida, including species new to the fauna of the United States (Diptera: Ceratopogonidae), pp. 1-59 in Insecta Mundi 2010 (147) on page 7, DOI: 10.5281/zenodo.535290
Attitude changes through art and sport
No full textThe question investigated by surveying mainstream Australians in Brisbane was whether studying Japanese floral art or a Chinese martial art changed their attitudes towards Asians or Asian culture. This was tested by an anonymous questionnaire with 44 questions. None of them began a course because of a special interest in Asia, yet eventually they learned about Asian culture and became interested in learning more. Several visited Asia after taking up their studies and the rest stated they now want to. While an attitude change could not be strongly demonstrated, a significant increase in knowledge about Asia, as well as an interest in Asian culture, was seen. Most were aware of anti-Asian attitudes in Australia’s past but few admitted such attitudes themselves, which may reflect the current view that such prejudice is not acceptable
Cnemaspis roticanai Grismer & Chan 2010
No full textCnemaspis roticanai Grismer & Chan, 2010 Roti Canai Rock Gecko Fig. 28 Holotype. ZRC 2.6860. Type locality: “ 743 m a.s.l. on Gunung Raya, Pulau Langkawi, Kedah, Peninsular Malaysia (06°22.114N, 99°49.270 E)” at 790 m in elevation. Diagnosis. Maximum SVL 47.0 mm; eight or nine supralabials; seven or eight infralabials; keeled ventral scales; 3–6 discontinuous, pore-bearing precloacal scales with round pores; 25–27 paravertebral tubercles; tubercles on flanks; tubercles in lateral caudal furrows; no ventrolateral caudal tubercles; caudal tubercles do not encircle tail; lateral caudal tubercle row absent; subcaudals keeled; median row of weakly enlarged subcaudal scales present; one or two postcloacal tubercles on each side of tail base; no enlarged femoral or subtibial scales; subtibials keeled; no enlarged submetatarsal scales on first toe; 26–29 subdigital fourth toe lamellae; light colored prescapular crescent; gular and pectoral regions, abdomen, underside of hind limbs, and subcaudal region yellow in males (Tables 6,7). Color pattern (Fig. 28). Males: dorsal ground color of head, body, limbs and tail pale-yellow; faint, brownish markings on top of head; single, diffuse, black, postorbital stripe extending to occiput and terminating at oblong, longitudinally oriented, yellow spot on nape followed by a pair of black, paravertebral spots on neck; rhomboidially shaped, brown, transverse markings between limb insertions extending onto tail as zig-zag-shaped, caudal bands; butterfly-shaped, pale-yellow interspaces between rhomboid markings; yellow, prescapular crescent followed by semi-transversely arranged, yellow bars on flanks separated by dark makings; forelimbs bearing yellowish blotches and scattered dark markings; hind limbs bearing yellowish blotches and dark markings resembling banding pattern; gular region yellowish orange; throat beige; abdomen, ventral surface of hind limbs, and subcaudal region yellow; ventral surface of forelimbs beige; all ventral scales bearing small, black stippling. Sexual dimorphism is marked in this species. Females: darker in overall coloration with much less yellow and a more contrasted dorsal pattern; dark markings on trunk appear as paravertebral blotches and in strong contrast to the pale-yellow interspaces; tail strongly banded; ventral surfaces yellowish throughout. Distribution. Cnemaspis roticanai is known only from Gunung Raya on Pulau Langkawi, Kedah, Peninsular Malaysia (Fig. 3). This species is expected to range more widely throughout the island. Natural history. Cnemaspis roticanai is a scansorial species occurring in open habitats with small, widely scattered rocks in hill dipterocarp forest above 400 m in elevation (Fig. 28). Grismer & Chan (2010) observed specimens on the underside of leaves, on tree trunks, and within cement drains. We hypothesize here that C. roticanai is a diurnal species being that the specimens we have observed at night were inactive and sleeping on tree trunks and the undersides of leaves. Others were found between rocks. Relationships. Cnemaspis roticanai is the sister species of C. omari sp. nov. (Fig. 2). Material examined. Malaysia: Kedah, Pulau Langkawi, Gunung Raya LSUHC 9453, ZRC 2.6860 – 62 (type series). Material examined since Grismer & Chan (2010): Kedah, Pulau Langkawi, Gunung Raya LSUHC 9430–31, 9439, 10802. Argus group. The argus group contains four species with a somewhat anomalous distribution pattern (Fig. 3). The basal species, Cnemaspis flavigaster Chan & Grismer occurs in central Peninsular Malaysia west of the Banjaran Titiwangsa mountains on the outskirts of Kuala Lumpur in Kepong, Ulu Gombak, and Batu Caves, Selangor (Chan & Grismer 2008) whereas the remaining three species, C. argus Dring and the sister species C. karsticola Grismer, Grismer, Wood & Chan and C. perhentianensis Grismer & Chan have restricted distributions in northeastern Peninsular Malaysia. Cnemaspis argus is known only from the mountainous region of Gunung Lawit (Dring 1979) and Gunung Tebu, Terengganu (Grismer et al. 2013c), C. karsticola is known from a single tower karst formation at Gunung Reng (Grismer et al. 2008b), and C. perhentianensis is endemic to two islands in the Perhentian Archipelago, Kelantan (Grismer & Chan 2008). The argus group is the sister lineage to the affinis group of central Peninsular Malaysia (Fig. 2) and is diagnosed by having a maximum SVL of 47.0– 65.2 mm; 7–10 supralabials; 6–10 infralabials; 6–10 contiguous, pore-bearing, precloacal scales with round pores; randomly arranged dorsal tubercles extending onto the lower flanks; 17–32 paravertebral tubercles; no caudal tubercles in lateral furrows; a lateral row of caudal tubercles; no tubercles encircling the tail; no ventrolateral caudal tubercles; no median row of enlarged or keeled subcaudal scales; 1–4 postcloacal tubercles on each side of the base of the tail; no enlarged femoral or subtibial scales; subtibials keeled; and 27–35 lamellae beneath the fourth toe.Published as part of Grismer, Lee, Wood, Perry L., Anuar, Shahrul, Riyanto, Awal, Ahmad, Norhayati, Muin, Mohd A., Sumontha, Montri, Grismer, Jesse L., Onn, Chan Kin, Quah, Evan S. H. & Pauwels, Olivier S. A., 2014, Systematics and natural history of Southeast Asian Rock Geckos (genus Cnemaspis Strauch, 1887) with descriptions of eight new species from Malaysia, Thailand, and Indonesia, pp. 1-147 in Zootaxa 3880 (1) on pages 58-60, DOI: 10.11646/zootaxa.3880.1.1, http://zenodo.org/record/494956
Chan-Sik Kim
No full text학위논문(박사)--아주대학교 일반대학원 :의학과,2014. 2I. INTRODUCTION 1
A. Age-related oxidative renal injury 1
B. AGEs and oxidative stress 2
C. High mobility group box protein-1 and receptor for AGE 3
D. Role of podocyte in glomerular pathobiology 3
E. Exercise and renal injury 4
F. Korean red ginseng and renal injury 5
G. Obesity-related renal injury 6
H. Aims of study 6
II. MATERIALS AND METHODS 8
A. KRG preparation 8
B. Animals and experimental design 8
C. Analysis of metabolic data 9
D. In vitro assay of the cross-linking of glycated proteins 10
E. Immunohistochemical staining 10
F. Double staining for TUNEL and Wilms tumor antigen-1 11
G. Apoptosis analysis 11
H. Statistical analysis 12
III. Results 13
A. Body weight and blood lipid profile 13
B. CML accumulation in renal tissues 16
C. Oxidative DNA damage in renal tissues 18
D. Apoptosis assay in renal tissues 20
E. Expression of Bax and Bcl-2 in renal tissues 22
F. Caspase-3 activation 25
G. Glomerular podocyte loss 27
H. Inhibitory effect of KRG on glycated proteins cross-linking in vitro. 31
I. Body weight and blood lipid profile 33
J. Oxidative DNA damage in renal tissues 36
K. Protein glycations in renal tissues 38
L. Apoptosis assay in renal tissues 40
M. HMGB1 cytoplasmic translocalization in renal tissues 42
N. RAGE Expression in renal tissues 44
IV. DISCUSSION 47
V. CONCLUSION 53
VI. REFERENCES 54
국문요약 67MasterA decline in renal function is seen commonly in aging. Aging further increase oxidative stress in the kidney and are associated with reduced renal function. Aging is progressive accumulation of oxidative agents. Advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs) formation has been implicated in the aging process. Obesity induced by a high-fat diet (HFD) may reduce renal function. However, the impact of obese on the age-related renal disease is not well understood. Exercise reduces oxidative stress. Korean red ginseng (KRG) has been reported to ameliorate oxidative tissue injury and has an anti-aging effect. The purpose of this study was to investigate whether HFD would accelerate ᴅ-galactose (GAL)-induced renal injury and to examine the preventive effects of a regular exercise and KRG on GAL/HFD -induced renal injury.
In the first experiment, age-related renal injury was induced by an administration with GAL (100 mg/kg, i.p.) in the absence or presence of high-fat diet (60% kcal as fat) for 9 weeks. The exercise group was trained on a motorized treadmill for 60 min/day, 5 times/week over the same period. In the second experiment, in vitro inhibitory effect of KRG on AGEs-cross-linking was examined by enzyme-linked immunosorbent assay (ELISA), and KRG (200 mg/kg/day) was given to GAL plus HFD-induced aging rats for 9 weeks.
Immunohistochemical staining for 8-OHdG (a specific marker of oxidative DNA damage) and CMLs (a marker of both glycation and lipoxidation reactions) revealed that GAL-treated rats fed a HFD showed aggravated renal injury associated with more pronounced renal AGEs/ALEs formation and oxidative DNA damage. In TUNEL assay, the numbers of TUNEL-positive cell in the GAL/HFD group were significantly higher than the GAL group. The expression of activated caspase-3 protein and Bax/Bcl-2 ratio also were significantly increased in the GAL/HFD group than that in the GAL group. Moreover, imuunohistochemical staining for synaptopodin and WT-1, well-known podocyte markers, revealed that HFD aggravates the loss of podocytes in renal glomeruli. However, the regular exercise restored all these renal changes in HFD plus GAL-treated rats.
KRG inhibited AGEs and collagen cross-link at ten-fold less concentration (IC50=55.65 μg/ml) than aminoguanidine (IC50=563.54 μg/ml), a well-known glycation inhibitor. When rats were fed with a HFD for 9 weeks in GAL-induced aging rats, renal AGEs accumulation, extracellular high mobility group box 1 protein (HMGB1), a signal of tissue damage) and receptor for AGE (RAGE) were extensively expressed in renal tissues of the GAL/HFD group than that in the GAL group. HMGB1 was clearly translocated from the nucleus to the cytoplasm in renal tubular epithelial cells. However, treatment of HFD plus GAL-induced aging rats with KRG restored all these renal changes.
In summary, when rats were fed with a HFD for 9 weeks in GAL-induced aging rats, oxidative DNA damage, protein glycations, renal cell apoptosis and cytoplasmic translocation of HMGB1 were caused in renal glomerular cells and tubular epithelial cells. However, the regular exercise and KRG treatment restored all these renal changes in GAL/HFD-treated rats. Therefore, this study suggested that long-term HFD may accelerate the deposition of AGEs/ALEs and oxidative renal injury in GAL-treated rats. This HFD-increased renal injury in GAL-induced aging rats could be suppressed by regular exercise and KRG through the repression of oxidative injury
An optimal initialization technique for improving the segmentation performance of Chan-Vese model
No full textIn level set method, initialization mode not only influences evidently the implementation efficiency but also relates directly to the final results. The paper presents an new initialization scheme for improving the segmentation performance of Chan-Vese model. The proposed initialization scheme consists of two stages. The first stage computes rough edges by using canny edge detection operator. The second stage removes noise edges and redundant edges by a morphological filter, and generates closed contours by iteratively connecting edge points according to a local cost function. In comparison with the primal Chan-Vese model, experimental data show that the Chan-Vese model equipped with our initialization scheme provides superior segmentation results and takes less computational cost
Comparison of personal and area sampling strategies in assessing workers’ exposure to vinyl chloride monomer
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