177,323 research outputs found

    Financial Analysis of FM Ceska, s. r. o.

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    This bachelor thesis is focused on financial analysis of FM Ceska, s. r. o. for the period 2005 - 2012, comparison of its financial indicators with selected competitors for the period 2009 - 2012 and an evaluation of the controlling company's influence on the economy and the financial indicators of FM Ceska, s. r. o. The thesis is divided in two parts - theoretical and practical. In the theoretical part there is described the procedure of financial analysis including its formulas and also the relationship between the controlling company and FM Ceska, s. r. o. The practical part contains vertical and horizontal analysis, financial ratios analysis, comparison with the competiton's financial indicators and the evaluation of the relationship between the controlling company and FM Ceska, s. r. o. The conclusion of the thesis is a complete rating of FM Ceska, s. r. o. based on the previous financial analysis

    Financial Analysis of FM Ceska, s. r. o.

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    Cílem této bakalářské práce je provedení finanční analýzy společnosti FM Česká, s. r. o. za období 2005 - 2012, porovnání jejích ukazatelů s vybranými konkurenčními společnsotmi za období 2009 - 2012 a také zhodnocení vlivu mateřské společnosti na hospodaření a finanční ukazatele společnosti FM Česká, s. r. o. Práce je rozdělena na dvě části - teoretickou a praktickou. V teoretické části je popsána finanční analýza včetně příslušných vzorců a také vztah mateřské a dceřiné společnosti. Praktická část obsahuje vertikální a horizontální analýzu, analýzu poměrových ukazatelů, porovnání ukazatelů s konkurencí a zhodnocení vztahu s mateřskou společností. Závěrem této práce je kompletní zhodnocení společnosti FM Česká, s. r. o. na základě provedené analýzy.This bachelor thesis is focused on financial analysis of FM Ceska, s. r. o. for the period 2005 - 2012, comparison of its financial indicators with selected competitors for the period 2009 - 2012 and an evaluation of the controlling company's influence on the economy and the financial indicators of FM Ceska, s. r. o. The thesis is divided in two parts - theoretical and practical. In the theoretical part there is described the procedure of financial analysis including its formulas and also the relationship between the controlling company and FM Ceska, s. r. o. The practical part contains vertical and horizontal analysis, financial ratios analysis, comparison with the competiton's financial indicators and the evaluation of the relationship between the controlling company and FM Ceska, s. r. o. The conclusion of the thesis is a complete rating of FM Ceska, s. r. o. based on the previous financial analysis

    Drug-drug interactions with statins : will pitavastatin overcome the statins' Achilles' heel?

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    Background: As the clinical complexity of patients at high cardiovascular risk and with multiple comorbid conditions increases, so does the potential for drug-drug interactions (DDIs). Large retrospective studies in various clinical settings have shown that an unacceptably large proportion of patients are coprescribed a statin with potentially interacting therapies, suggesting that the impact of polypharmacy on the safety profile of statins may be underappreciated. Scope: To assess the evidence for the burden of DDIs and related adverse drug reactions (ADRs) with current statins relative to pitavastatin, a new agent recently approved in the USA and EU. Methods: Structured review of the PubMed and EMBASE databases (to 15 October 2010) for literature on statins in the areas of ADRs, polypharmacy and DDIs; pharmacokinetics, and pitavastatin clinical safety and efficacy. Findings: Patients who are on statin therapy are often receiving multiple medications for comorbid conditions, and so are at increased risk of ADRs, such as myopathy, because of pharmacokinetic interactions at the level of cytochrome P450 (CYP) enzymes and/or organic anion-transporting polypeptides. Pitavastatin has a distinctive metabolic profile that means it is marginally metabolised by CYP enzymes, and is therefore expected to have a low risk of DDIs and related ADRs. A large post-marketing study conducted in more than 20,000 patients in Japan has demonstrated that the rate of DDIs with pitavastatin treatment may compare favourably with that observed with atorvastatin and rosuvastatin. Conclusions: The addition of pitavastatin to the range of available statins provides prescribing physicians with a new treatment option that is expected to have a low risk of DDIs and related ADRs. This, coupled with the demonstrated efficacy of pitavastatin in reducing low-density lipoprotein cholesterol, should help physicians individualise lipid-lowering regimens based on the patient profile and concomitant medications

    Vypocet frekvenci a tvaru vlastniho kmitani estakady SO 5102 Parnik -Dlouha Trebova na tratovem useku Usti nad Orlici - Ceska Trebova.

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    A new railway bridge SO 5102 Parnik - Dlouha Trebova was built on the railway track Praha - Ceska Trebova on the 250th km of the track section Usti nad Orlici - Ceska Trebova. Dynamic calculation of this bridge was done as the basis for the dynamic load test. The main aim of the dynamic calculation was determination of theoretical modal characteristics (natural frequencies and natural modes ) of the bridge.Available from STL Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Letter from R. R. Zellick, Assistant Trust Officer, Anglo California National Bank of San Francisco, to Joseph R. Goodman, October 2, 1942

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    Letter from R. R. Zellick, Assistant Trust Officer at The Anglo California National Bank of San Francisco, to Joseph R. Goodman, regarding property owned by Dave Tatsuno. Zellick mentions a dispute between current tenants and Tatsuno, and that Tatsuno has asked Goodman to help locate trustworthy tenants.Personal correspondence, organizational records, government documents, publications, and other papers created or collected by Joseph R. Goodman documenting the forced removal and incarceration of Japanese Americans during World War II, as well as organized resistance to incarceration. Included in the collection are records of the Japanese Young Men's Christian Association and the Japanese American Citizens' League in San Francisco, including papers of the Japanese YMCA's executive secretary Lincoln Kanai; Sakai family papers; Goodman's correspondence to and from Japanese American incarcerees, organizations opposing forced removal and incarceration of Japanese Americans, the War Relocation Authority, and others; publications, photographs, and ephemera from the Topaz Relocation Center, where Goodman taught high school; War Relocation Authority records and publications; and newspaper clippings, pamphlets, and reports about forced removal and incarceration created by various government, religious, and civic organizations, in California and nationwide

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    An Appreciation of the Impact of the Development of Financial Markets on Financial Decisions made by Corporations in the Czech Republic

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    The article attempts to evaluate the main influences on how money and capital markets have affected corporate finance and treasury in the Czech Republic. There are 5 primary factors identified, which at various times have been suspected of exerting significant influence over corporate financial decisions, i.e.: tax system evolution, interest rates changes, legislative framework, competitive environment in the sector of financial intermediates, pressure from the corporations on the banks towards improved quality of the treasury products offered (this article focuses on the influence of 3 of them). Recent changes in Czech financial markets have had a lasting impact on both financial intermediaries and corporate finance departments and treasuries. And many more changes may be expected to occur in the future, especially in connection with Czech Republic European Union accession in May 2004, and its subsequent incorporation into the Eurozone
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