1,721,002 research outputs found
Ruolo dell'eritropoietina nel trattamento del vasospasmo cerebrale: stato dell'arte. SINCH
No full textUtilizzo di un nuovo sistema di coagulazione bipolare nella chirurgia dei meningiomi. Nota tecnica
No full textRaro caso di intolleranza al sistema di stimolazione spinale: Ruolo delle condizioni psicosomatiche.
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Neuronavigated-biopsy in the diagniosis of demyelinating pseudotumoral brain lesions. Case report.
No full textIntroduction: Pseudotumoral-demyelinating lesions are typically characterized by severe difficulties in differential diagnosis from gliomas, metastatic tumors and abscesses. Marburg’s disease (MD) is an extremely rare and aggressive form of Mutiple Sclerosis (MS) with acute onset, rapid neurological deterioration, and poor prognosis. MRI images often show pseudotumoral lesions characterized by mild and focal or, sometimes, ring enhancement. Perhaps, radiological aspect can vary, making necessary hystopathological confirmation.
Objectives: There is increasing interest in the role of surgical biopsy for a correct and early diagnosis of pseudotumoral demyelinating lesions. We report an histopathologically confirmed case of MD. Thanks to the analysis of actual literature, our purpose is to ameliorate diagnostic criteria, the timing of treatment and, subsequently, the prognosis of patients affected.
Matherials and methods: A 24 years-old woman presented with a sudden onset of motor subaphasia and numbness to the right hemiface, followed, in a few hours by rapid deterioration with mild pyramidal right hemiparesis and complete aphasia. Patient underwent to a CT brain examination which showed three unspecific hypodense lesions: the bigger one, in the left subcortical frontal white matter, and two smaller lesions in the deep parietal and in the right paratrigonal white matter. For better characterization, a brain MRI was performed. The lesions in the right paratrigonal and left parietal white matter where appreciable as highly hyper-intense on TSE-T2 and FLAIR-T2 sequences, hypo-intense on TSE-T1, and responsible for a moderate mass effect on the surrounding structures; the left parietal white matter lesion also showed an incomplete and irregular ring-enhancement. The left subcortical frontal lesion was only mild hyper-intense on TSE-T2 and FLAIR-T2 but strongly hyper-intense on DWI, and a subsequent MRI scan showed a pseudotumoral development with an atypical patchy enhancement. Total body CT scan, auto-antibodies and viral serology on blood and CSF were negative. Isoelectric focusing in agarose gel detected the presence of CSF oligoclonal bands. Steroids were administrated without significant improvement. On the basis of the obtained data, and in consideration of the poor responsiveness to steroids, we performed a neuronavigator-aided biopsy of the main lesion through an open microsurgical approach. Preoperative planning was performed the day before by using contrast agent-enhanced brain CT scan, after positioning markers on the scalp. The exam was then transferred on a data storage device to insert CT images on the neuronavigator. The principal landmarks were used to realize a temporal craniotomy and a small corticectomy centred on the lesion. Finally, we detected, at a depth of about 2 cm, a pathological curdy and whitish tissue, ablated in small fragments and sent for hystological examination. A post-operative CT scan excluded any complications and the patient had a regular course. At demission, neurological exam was slightly better with partial regression of hemiparesis and partial amelioration of speech function. Hystopathological report confirmed the hypothesis of Marburg’s variant of MS.
Results and Conclusions: Initial therapeutic approach to MS is pharmacological. However, in some atypical cases, CSF analisys, MRI images and/or clinical course after sterioids administration are not sufficiently diagnostic to completely rule out tumors or abscesses. So, early biopsy is an unavoidable necessity for the differential diagnosis of pseudotumoral-demyelinating lesions, to prevent inappropriate surgical or irradiative treatments and ameliorate the prognosis
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