1,720,983 research outputs found
Il trial clinico: dai grandi numeri al singolo individuo: il punto di vista del neurologo
No full textDepositional evolution of a tectonically-confined proximal-foredeep deep-marine system: Miocene Serra Palazzo Formation (Southern Apennines, Italy)
No full textThe Miocene Serra Palazzo Formation (SPF) was deposited in a foredeep basin in front of the growing Southern Apennines orogenic wedge. A new detailed facies analysis, based on high-resolution physical stratigraphy, for a 570 m-thick interval, has been undertaken in order to reconstruct the depositional history. Two phases of development can be recognized. The older one was characterized by the sedimentation of sandy channel-lobe transition zone (cltz) deposits with various degrees of amalgamation; roughly in the middle, a 26 m-thick sandy megaturbidite was deposited. At this time, basin topography, including the inbound slope base and topography due to the orogen-related flexural subsidence, caused significant flow confinement illustrated by a number of sedimentary features, such as syn-sedimentary deformation structures, hummocky laminations, and differences in the palaeocurrent directions recorded in the same event bed. The younger phase was characterized by the sedimentation of more-proximal amalgamated sandy channel deposits, followed upwards by an even more-proximal sequence of thick levees with thin-bedded and fine-grained facies. Tectonics was one of the main controls on the stacking patterns of the submarine fans of the SPF basin. Particularly, the outward thrust migration governed the evolution from the cltz deposits to the levee deposits and it might have caused the repeated waxing-waning flow cycles recorded in the channel deposits and the changes in bed dip angles in the levee deposits
Gender and stroke: acute phase treatment and prevention
No full textStroke is the third most common cause of death in women and a major cause of disability. Many aspects of stroke are similar in men and women, including clinical presentation, main risk factors, and distribution of the main subtypes. There are, however, some gender differences and specificities in stroke including some aspects related to treatment. Women are less likely to receive thrombolysis than men; however, in treated cases, the efficacy of intravenous thrombolysis is higher in women than in men. Hormone replacement therapy has been suggested as a possible strategy to reduce the occurrence of stroke in postmenopausal women but several clinical trials failed to show any benefit in stroke and cardiovascular disease prevention. Also in stroke prevention with antiplatelets there emerge some important gender differences: in primary prevention of stroke, aspirin was effective in women but not in men while in secondary prevention no gender differences were found with any of the available antiplatelet agents
Detailed field mapping and revised litho-biostratigraphy of the Castelvetere Formation cropping out at the NW Campania-Basilicata border (Southern Apennines, Southern Italy)
No full textDepositional record of confined turbidites in syn-subduction intraslope basin: insight from the Tufiti di Tusa Formation (Southern Apennines, Italy)
Full text linkA detailed lithostratigraphy and facies analysis of a type section of the Tufiti di Tusa Formation, including deepmarine
clastic successions with syn-orogenic volcanic detritus and deposited in the late Eocene - early Miocene
basin system at the front of the growing Maghrebian - Southern Apennines orogen, is discussed in the paper.
Based on facies analysis and composition, the study section was subdivided into the following units, from bottom
to top: Unit I, mostly formed by contained-reflected beds (including a bed similar to the Contessa megabed of the
Marnoso-arenacea Formation in the Northern Apennines), with the ratio of sandstone intervals to mudstone
intervals (S/M) of 0.6 and with mostly-calciclastic sandstone to siltstone fraction; Unit II, recording a moderate
decrease in contained-reflected beds and a moderate increase in slurry beds, with S/M ratio of 0.9, and with
mostly-siliciclastic sandstone to siltstone fraction; Unit III, recording a further decrease in contained-reflected
beds and an evident increase in slurry beds and very-thick beds with a basal massive very coarse to coarsegrained
sandstone, with S/M ratio of 2.5, and with mostly-volcaniclastic sandstone to siltstone fraction.
In accordance with the depositional models for the infill of confined turbidite basins, Units I and II are here
interpreted as representing a flow ponding depositional phase, while Unit III as iconic of a flow stripping
depositional phase. The compositional variation from Unit I to Unit II records cutoff of calciclastic supply from
underplate sources, possibly tied to tectonic uplift of the external basin margin; while that from Unit II to Unit III
records sudden availability of volcaniclastic sediment possible due to burial of morphological high(s) between
the internal volcanic arc (source of the volcaniclastic sediment) and the depositional basin, and/or establishment
of tectonically-controlled conduits cutting the above high(s). This study may improve the knowledge not only of
infilling evolution of confined turbidite basins, but also of the depositional setting of the late Paleogene Southern
Apennines subduction margin in the Central Mediterranean
New geological map at a 1:10.000 scale and tectono-stratigraphic review of the NW Campania-Basilicata boundary (Southern Apennines, Southern Italy)
No full textComorbid neuropathologies in migraine: an update on cerebrovascular and cardiovascular aspects
No full textSeveral conditions are comorbid with migraine; our review is focused on the relation between migraine, and cerebrovascular and cardiovascular diseases. Despite many studies showed an association between migraine and patent foramen ovale, it is still not known whether its presence might be causal for the migraine pathogenesis and currently its closure cannot be recommended for migraine prevention. On the contrary, conflicting epidemiological data link migraine to arterial hypertension and the use of antihypertensive agents acting on the renin-angiotensin system sounds promising in migraine prevention. A complex bidirectional relation exists between migraine and stroke, and new evidences show a clear association between migraine and coronary heart disease. In both conditions, migraine represents a defined risk factor although the magnitude of the risk varies across the different studies. However, since the risk is low in the general population, it is not possible to identify which migraineurs will develop a cardiovascular or a cerebrovascular event making difficult to apply preventive measures
Depositional evolution of a tectonically‐confined proximal‐foredeep deep‐marine system: Miocene Serra Palazzo Formation (Southern Apennines, Italy)
No full textThe Miocene Serra Palazzo Formation (SPF) was deposited in a foredeep basin in front of the growing Southern Apennines orogenic wedge. A new detailed facies analysis, based on high-resolution physical stratigraphy, for a 570 m-thick interval, has been undertaken in order to reconstruct the depositional history. Two phases of development can be recognized. The older one was characterized by the sedimentation of sandy channel-lobe transition zone (cltz) deposits with various degrees of amalgamation; roughly in the middle, a 26 m-thick sandy megaturbidite was deposited. At this time, basin topography, including the inbound slope base and topography due to the orogen-related flexural subsidence, caused significant flow confinement illustrated by a number of sedimentary features, such as syn-sedimentary deformation structures, hummocky laminations, and differences in the palaeocurrent directions recorded in the same event bed. The younger phase was characterized by the sedimentation of more-proximal amalgamated sandy channel deposits, followed upwards by an even more-proximal sequence of thick levees with thin-bedded and fine-grained facies. Tectonics was one of the main controls on the stacking patterns of the submarine fans of the SPF basin. Particularly, the outward thrust migration governed the evolution from the cltz deposits to the levee deposits and it might have caused the repeated waxing-waning flow cycles recorded in the channel deposits and the changes in bed dip angles in the levee deposits
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