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Pityriasis rotunda in childhood.
Abstract
Pityriasis rotunda is a rare disease characterized by round or oval patches, localized mainly on the trunk, arms, and legs. The patches are usually lighter than the surrounding skin, but sometimes may be darker, and are covered by fine, adherent scales. Two types of pityriasis rotunda have been described. Type I has been observed mainly in oriental and black patients older than 60 years of age, and is often associated with systemic disease or malignancy. Type II has been observed in white patients younger than 40 years of age, is often familial, and has never been observed in association with malignancy or internal disease. On Sardinia, a cluster of patients with type II pityriasis rotunda has been described. From 1981 until 1998, 51 cases of this disease have been observed in the Department of Dermatology, University of Sassari; 32 of them were children. The great prevalence of pityriasis rotunda on Sardinia, an island which until 40 years ago had limited contact with the Italian mainland, and the presence of a large number of familial cases suggest that type II pityriasis rotunda should be considered a genetically determined disease. The trend toward spontaneous resolution after the age of 20 years suggests that pityriasis rotunda should be considered a genodermatosis with a temporary phenotypic expression
Osservazioni sull'attività degli enzimi del metabolismo dei carboidrati nel basalioma
L’attività della esochinasi, della lattico-deidrogenasi, della isocitrico-deidrogenasi, dell’enzima malico, delle 6-fosfogluconico-deidrogenasi, dell’alanina-transaminasi e delle aspartato-transaminasi è stata studiata in 10 basaliomi con metodi di istochimica quantitativa. L’attività di tutti gli enzimi studiati risulta aueentata nel basalioma rispetto alla cute normale, ma tale dato non deve essere considerato indice di malignità, perché risulta di maggiore entità di quello osservato in 10 melanomi maligni studiati per confront
Le neoplasie cutanee
The man features of the skin tumours have bene described in the present paper.Aetiologic, clinic, histopathologic, prognostic and therapeutic aspects of basal cell and squamous cell carcinomas are taken into consideration. Pur experience confirms the importante of ecologica factors in the patogenesi of these carcinoma s: solar keratosis, actinic cheilitis may be' considered obbligatory precancerosi s
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