1,720,980 research outputs found
GUILLAIN-BARRe SYNDROME AS A PARANEOPLASTIC PRESENTATION OF ADENOCARCINOMA OF ENDOMETRIUM
No full textGUILLAIN-BARRe SYNDROME ...
Is it possible to predict the outcome of endovascular thrombectomy for hyperdense middle cerebral artery sign at the time of first admission?
No full textBackground: The hyperdense middle cerebral artery sign (HMCAS) on admission non-contrast computed tomography (NCCT) is a well-characterized phenomenon in acute ischemic stroke. Aim: The purpose of this study is to determine the impact of HMCAS on the outcome of patients who underwent endovascular thrombectomy. Materials and Methods: A retrospective analysis of a prospectively collective database included 136 consecutive patients with anterior circulation acute ischemic stroke who underwent endovascular thrombectomy. We collected the demographics, and clinical and brain imaging as well as functional and imaging outcomes data at baseline. Patients were divided into two groups with hyperdense artery sign and those without the sign. The difference between the two groups in terms of mortality and prognosis was analyzed. Results: There were 136 patients, 50.7% of them were women. The mean age was 59.1 years. The subgroup with HMCAS present consisted of 93 patients. There were no differences in demographics and clinical characteristics between the two groups; however, tobacco use is more common in patients with HMCAS. No significant difference was observed in clinical outcomes and mortality between the two groups at 3 months. Patients with HMCAS had statistically more new territory emboli during the procedure (9.7%) compared to patients without HMCAS. Conclusion: We showed that the presence of HMCAS in initial CT was not helpful in predicting good clinical outcomes in patients undergoing endovascular therapy patients. However, the presence of HMCAS is related to more new territory embolism during the procedure. Different endovascular strategies may be applied to these patients
The frequency of silent brain infarcts in polycythaemia vera and essential thrombocytosis
No full textAim: Stroke or transient ischaemic attack in Ph chromosome-negative myeloproliferative neoplasms patients have been investigated many times, whereas there is limited research on silent brain infarcts. In our study, we explored the frequency of silent brain infarcts in a polycythaemia vera (PV) and essential thrombocytosis (ET) patient group and its relationship to disease-related factors. Methods: The study was designed retrospectively. PV and ET patients who were followed up between 2015–2021 were re-examined in terms of silent brain infarcts. There were 66 PV and ET patients who had an MRI scan of the brain. Nine patients were excluded due to symptomatic cerebrovascular disease, 25 were excluded due to having one or more of the following diseases or conditions: arterial hypertension, diabetes mellitus type 2, migraine, smoking, carotid stenosis. Results: JAK-2 (Janus Kinase-2) mutation was observed in 23 patients (67.6%) and silent cerebral ischaemia was detected in 22 patients (35.3%). The rate of JAK-2 mutation in patients with silent cerebral ischaemia was found to be statistically higher than those without (P = 0.027). The relationship between remission status and silent cerebral ischaemia was also found to be statistically significant, patients in the remission period having a lower rate of silent cerebral ischaemia (P = 0.036). Conclusion: The findings of mean age and silent cerebral infarction frequency support the theory that PV and ET are also risk factors of silent brain infarction and need to be screened during the follow-up term
Hastanede Yatan Akut İnmeli Hastalarda Gastrostomi: “NöroTek” Türkiye Nokta Prevalans Çalışması Alt Grup Analizi
No full textObjective: Nutritional status assessment, dysphagia evaluation and enteral feeding decision are important determinants of prognosis in acute neurovascular diseases. Materials and Methods: NoroTek is a point prevalence study conducted with the participation of 87 hospitals spread across all health sub regions of Turkey conducted on 10-May-2018 (World Stroke Awareness Day). A total of 972 hospitalized neurovascular patients [female: 53%, age: 69 +/- 14; acute ischemic stroke in 845; intracerebral hematoma (ICH) in 119 and post-resuscitation encephalopathy (PRE) in 8] with complete data were included in this sub-study. Results: Gastrostomy was inserted in 10.7% of the patients with ischemic stroke, 10.1% of the patients with ICH and in 50% of the patients with PRE. Independent predictors of percutaneous endoscopic gastrostomy (PEG) administration were The National Institutes of Health Stroke Scale score at admission [exp (ss): 1.09 95% confidence interval (CI): 1.05-1.14, per point] in ischemic stroke; and mechanical ventilation in ischemic [exp (ss): 6.18 (95% CI: 3.16-12.09)] and hemorrhagic strokes [exp (ss): 26.48 (95% CI: 1.36-515.8)]. PEG was found to be a significant negative indicator of favorable (modified Rankin's scale score 0-2) functional outcome [exp (ss): 0.032 (95% CI: 0.004-0.251)] but not of in-hospital mortality [exp (ss): 1.731 (95% CI: 0.785-3.829)]. Nutritional and swallowing assessments were performed in approximately two-thirds of patients. Of the nutritional assessments 69% and 76% of dysphagia assessments were completed within the first 2 days. Tube feeding was performed in 39% of the patients. In 83.5% of them, tube was inserted in the first 2 days; 28% of the patients with feeding tube had PEG later. Conclusion: The NoroTek study provided the first reliable and large-scale data on key quality metrics of nutrition practice in acute stroke in Turkey. In terms of being economical and accurate it makes sense to use the point prevalence method.Amaç: Akut nörovasküler hastalıklarda nütrisyonel durum ve disfaji değerlendirmesi ve enteral beslenme kararı önemli prognoz belirleyicilerindendir.
Gereç ve Yöntem: NöroTek, 10 Mayıs 2018’de (Dünya İnme Farkındalık Günü) Türkiye’nin tüm sağlık alt bölgelerine yayılmış 87 hastanenin katılımıyla
gerçekleştirilen bir nokta prevalans çalışmasıdır. Hastanede yatan ve bu alt çalışma için toplanan verisi tam olan toplam 972 nörovasküler hasta (kadın: %53, yaş:
69±14 yıl; 845’i akut iskemik inme; 119’u intraserebral hematom ve 8’i post-resüsitasyon ensefalopatisi) analiz edildi Bulgular: Gastrostomi iskemik inmeli hastaların %10,7, intraserebral kanamalıların %10,1 ve post-resusitasyon ensefalopatisi olanların %50’sine uygulanmıştır.
Perkütan endoskopik gastrostomi (PEG) gereksiniminin bağımsız belirleyicileri, iskemik inme grubunda kabul NIHSS [exp (β): 1,09, %95 güven aralığı (GA):
1,05-1,14, puan başına] ile hem iskemik hem de hemorajik inmelerde mekanik ventilasyon uygulanmış olmasıdır [iskemik için: exp (β): 6,18, %95 GA: 3,16-
12,09] ve hemorajik inme için: [exp (β): 26,48, 95% GA: 1,36-515,8]. İnme olgularında PEG uygulaması hastane içi mortalite için bağımsız belirleyici değildi
[exp (β): 1,731, 95% GA: 0,785-3,829]. Ancak, PEG uygulanmış olması taburculuk esnasında iyi prognoza (modifiye Rankin skoru 0-2) sahip olabilme için
anlamlı bir negatif etmen olarak bulundu [exp (β): 0,032, %95 GA: 0,004-0,251]. Hastanede yatan nörovasküler hastaların yaklaşık üçte ikisinde malnütrisyon
ve yutma bozukluğu açısından değerlendirme yapılmıştı. Nutrisyonel status değerlendirmesinin %69’u ve disfaji değerlendirmesinin %76’sı ilk 48 saat içinde
gerçekleştirilmişti. Tüple enteral nütrisyon uygulama oranı %39’du. Beslenme tüplerinin %83,5’i ilk 2 gün içinde yerleştirilirken beslenme tüpü olan hastaların
%28’ine daha sonra PEG açılmıştı.
Sonuç: NöroTek çalışması ile Türkiye’de hastanede yatan akut inme hastalarında nutrisyonel uygulamaların temel kalite ölçütlerine ilişkin ilk güvenilir ve büyük
ölçekli veri sağlanmıştır. Ekonomik olması ve doğruluğu açısından nokta yaygınlık yönteminin bu tip verilerin temini için daha fazla kullanılması mantıklıdır
TEKRARLANAN DIFÜZYON AĞIRLIKLI GÖRÜNTÜLEMEDE HIPOKAMPAL HIPERINTENSITE SAPTANAN IKI GEÇICI GLOBAL AMNEZI OLGUSU: OLGU SUNUMLARI
No full textAn episode of temporary memory loss which is recovered within 24 hours is called transient global amnesia. The etiology and triggering factors are unclear but hippocampal lesions may contribute to this condition. Diffusion-weighted magnetic resonance imaging is used to detect these lesions. In this case report, two cases with transient global amnesia who had hippocampal lesions are presented.Geçici global amnezi, 24 saat içinde iyileşen geçici hafıza kaybı ataklarıdır. Etyolojisi ve tetikleyici faktörleri aydınlanmış değildir ancak hipokampal lezyonlar geçici global amneziye katkıda bu- lunabilir. Bu lezyonları saptamak için difüzyon ağırlıklı manyetik rezonans görüntüleme kullanılır. Bu olgu sunumunda hipokam-pal lezyonu olan geçici global amnezili iki olgu sunuldu
Esansiyel tremorlu hastalarda klinik ve elektrookülografik bulgular
No full textÇalışmamızda, Esansiyel tremor (ET) hastalarında göz hareketlerini elektrookülografi (EOG) ile kayıtlamak, patoloji saptanırsa; ET patofizyolojisinde özellikle son çalışmalarda üzerinde durulan serebellar disfonksiyon başta olmak üzere, beyin sapı, talamus ile yolaklarındaki disfonksiyonunun, bu yolaklardaki disfonksiyon sonucunda ortaya çıkabilen göz bulguları ile karşılaştırmak amaçlandı. Ocak 2008 ve Ekim 2008 tarihleri arasında Pamukkale Üniversitesi Tıp Fakültesi Nöroloji polikliniğine başvuran 36 ET'li hasta ile benzer cinsiyet ve yaşta 36 sağlıklı katılımcı çalışmaya alındı. Tüm katılımcıların EOG testlerinden sakkadik test, yavaş takip (trekking) testi, optokinetik test, gaze testi ve pozisyonel testti yapılarak öykü ve muayene bulgularıyla birlikte değerlendirildi. ET'li hasta ile kontrol grubu arasında, EOG testlerinde anlamlı bir farklılık saptanmadı. Bu durumda ET nin patogenesisinde öne sürülen serebellar hipotezi destekler veri elde edemediğimiz söylenebilir ancak bu durum hipotezi reddettirmez. Oküler bulgu çıkartmayacak düzeyde bir patoloji sözkonusu olabilir.The aims of the study were to record ocular movements of Essential tremor (ET) patients using electrooculography (EOG) and; if there are any pathological results, to compare them with the ocular manifestations of the recently investigated causes of ET such as brainstem, thalamus disfunction and especially cerebellar disfunction. Thirty six ET patients admitted to Pamukkale University Neurology department between January 2008 and October 2008 were recruited for the study and 36 healthy, age and sex matched subjects formed the control group. Saccadic, tracking, optokinetic, gaze and positional test results were obtained from the EOG tests of the each subject and evaluated together with the history and examination findings. There was not any significant difference between the ET patients and controls. Those results may not lead us to support cerebellar hypothesis in the pathogenesis of ET. On the other hand they can not discard the hypothesis
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
- …
