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Editorial: The importance of the body-mind relationship in mental functioning and development of body-focused disorders in adolescence
Muscle Dysmorphia: a comparison between competitive bodybuilders and fitness practitioners
Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production.
Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production.
Mulatero P1, Glorioso N, Fallo F, Soro A, Morra di Cella S, Carra R, Filigheddu F, Veglio F.
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Abstract
OBJECTIVE:
11beta-Hydroxylase and aldosterone synthase are two highly homologous genes involved in different forms of human hypertension and in different animal models of hypertension. It has been shown that the conservative substitution D147E in the human CYP11B2 gene results in an increased production of corticosterone and aldosterone in vitro. A gene conversion between the CYP11B1 and CYP11B2 genes could be responsible for such a substitution.
METHODS:
In this study we investigated the presence of the mutation D147E of CYP11B2 in a group of 128 patients with primary aldosteronism, 68 patients with essential hypertension and increased corticosterone production and in 48 normal volunteers.
RESULTS AND CONCLUSIONS:
We did not identify any patient carrying this mutation, indicating that if it exists it is very rare and so has no relevance in determining the increased steroid excretion seen in some subtypes of human hypertension
Che fa il coccodrillo?
Nell'articolo vengono presentate le linee metodologiche di un progetto di educazione alla lettura, attraverso i libri illustrati, attivato per più anni nella scuola dell'infanzia di Ravascletto (Ud), proposto e coordinato dalla scrivente. Vengono presentati i risultati ottenuti, riportando parti di trascrizione da registrazioni eseguite in classe. Si tratta di una R-A pluriennale
Unique and shared correlates of disordered eating and non-suicidal self-injury among school-based adolescents
Parental bonding, eating attitudes, body modifications and self-injurious behaviors in a natural sample of 3158 adolescents
Influence of gender role orientation (masculinity versus femininity) on body satisfaction and eating attitudes in homosexuals, heterosexuals and transsexuals
The primary aim of this study was to investigate the relationship between gender role orientation and eating disorder attitudes and behaviors and body dissatisfaction in a sample of homosexuals, heterosexuals, and transsexuals.
We screened 132 homosexuals, 178 heterosexuals (both male and female), and 15 MtF transsexuals by means of an ad hoc socio-demographic schedule; the Eating Disorders Inventory-2 and Symptom Checklist; the Body Uneasiness Test and the Bem Sex Role Inventory.
Differences between homosexual, heterosexual, and transsexual participants emerged, but those data seem to be best explained by the constructs of femininity and masculinity than by the biological gender.
The empirical evidence of a positive correlation between femininity and eating problems, and the negative correlation between masculinity and eating problems, is full of implications. Eating disorders appear to be diseases of femininity; masculinity seems to be a protective factor, independently by the biological gender
How perceived parental bonding affects self-concept and drive for thinness: A community-based study
The main aims of the present study were to investigate the relationship between perceived parental bonding and self-concept, and whether these variables have an effect on eating disturbances vulnerability by testing a mediation model. We screened 3158 Italian high school students (1132 males and 2026 females), ranging in age from 14 to 18 years old, by means of self-report measures of parental behavior as perceived by the offspring, eating disturbance propensity and self-concept. Weight and height were also measured. The link between a parental bonding behavior characterized by low paternal care and by maternal overprotection and a dysfunctional eating attitude (expressed by the drive for thinness) resulted significant and was found to be perfectly mediated by adolescents’ self-concept. Moreover, our results showed that the impact of self-concept for the drive for thinness (and hence on eating psychopathologies) is moderated by the participants’ body mass index and gender, but not by age. We consider this evidence of study to be useful for the prevention and treatment of eating related problems in adolescence
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