1,721,250 research outputs found

    Tommaso de’ Cavalieri e i monumentali soffitti lignei di Flaminio Boulanger

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    Il contributo porta alla luce il costante e assiduo rapporto tra il nobile Tommaso de' Cavalieri e l'intagliatore Flaminio Boulanger, evidenziando quanto le commissioni affidate al falegname fossero dipendenti dalle scelte di gusto dell'amico di Michelangelo

    Franco Angiolini, I cavalieri e il principe. L'ordine di Santo Stefano e la società toscana in età moderna

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    Rouchon Olivier. Franco Angiolini, I cavalieri e il principe. L'ordine di Santo Stefano e la società toscana in età moderna. In: Revue d’histoire moderne et contemporaine, tome 46 N°4, Octobre-décembre 1999. pp. 808-811

    Franco Angiolini, I cavalieri e il principe. L'ordine di Santo Stefano e la società toscana in età moderna

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    Rouchon Olivier. Franco Angiolini, I cavalieri e il principe. L'ordine di Santo Stefano e la società toscana in età moderna. In: Revue d’histoire moderne et contemporaine, tome 46 N°4, Octobre-décembre 1999. pp. 808-811

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Involvement of mitochondrial permeability transition pore opening in alpha-bisabolol induced apoptosis.

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    α-Bisabolol is a natural monocyclic sesquiterpene alcohol. It has been used in cosmetics for hundreds of years because of its perceived skin-healing properties. α-Bisabolol is known to have anti-irritant, anti-inflammatory and antimicrobial properties. In precedent studies, we described how α-bisabolol exerts a selective pro-apoptotic action towards transformed cells [Cavalieri E et al. (2004) Biochem Biophys Res Commun315, 589-594] and its uptake is mediated by lipid rafts on the plasma membrane [Darra E et al. (2008) Arch Biochem Biophys476, 113-123]. In this study, we hypothesize that the intracellular target of α-bisabolol may be the mitochondrial permeability transition pore (mPTP). To evaluate this hypothesis, we used one transformed cell line (human glioma T67) in comparison with a nontransformed one (human fibroblasts). We assessed the effect of a specific mPTP inhibitor (cyclosporine A) on the toxic action of α-bisabolol. Results show that the α-bisabolol-induced decrease in oxygen consumption is abolished by the addition of cyclosporine A in T67 cells, indicating that α-bisabolol may target mPTP. The central role of mitochondria was also demonstrated by using galactose to force cells to a more aerobic metabolism. In this condition, we observed higher α-bisabolol toxicity. Furthermore, we studied the effect of α-bisabolol on isolated rat liver mitochondria. This study expands the notion of the specific action of α-bisabolol on transformed cells and suggests that it may act by disturbing the structure and function of the mPTP. α-Bisabolol toxicity is clearly related to its cellular uptake, which is higher in transformed cell lines

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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