76 research outputs found

    Southern Lit 101: An Artists\u27 Talk

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    An Exhibition of Literary Quilts. Cathy Fussell and Fred Fussell

    A guide to the choral music of Chales Fussell

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    Thesis (D.M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at [email protected]. Thank you.Over a span of nearly fifty years Charles Fussell (b. 1938) has created a choral catalog of fifteen works, ranging from choral symphonies to folk song settings. Fussell's keen interest in literature has led him to diverse sources for his texts, such as Walt Whitman, May Sarton, Hart Crane, and Allen Ginsberg. Widely recognized among his peers for his technical prowess and enduring musicality, Fussell has yet to be embraced by the greater community of choral conductors and ensembles. This study is intended to be a guide to, and a summation of, Fussell's choral works from the mid-1960s to the present. The preface summarizes the author's reasons for selecting Charles Fussell's choral music as a research topic and the process that led to the completion of this document. Part I is devoted to the subject's biography, which is based on interviews with Fussell and those who have played a significant role in his musical life. Part II, "A Survey of the Choral Music of Charles Fussell," is divided into three sections, each dedicated to a particular subgroup of Fussell's choral music. Section A describes the shorter choral pieces in detail, offering background information on the genesis of each composition and its text, as well as a structural and thematic overview. In the same format, Section B discusses four dramatic works that include choral writing, and Section C covers Fussell's three major choral-orchestral works. Part III, entitled "Musical Elements in the Choral Music of Charles Fussell," identifies key motives and musical gestures that are found throughout Fussell's choral pieces. The two appendices are designed to aid conductors and singers who are interested in Fussell's choral music. Appendix A offers basic information on each piece, such as duration, orchestration, publisher information, and available recordings, and Appendix B is a compilation of all the texts used by Fussell in his choral works

    Four data discourses and assemblage forms: a methodological framework

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    Over nearly a decade, Critical Data Studies (CDS) scholars have interrogated a range of framings of data that struggle for discursive dominance. This paper argues that four discourses have emerged: data as an asset, data as latent knowledge, data as a technology of governing, and data as resistance. These four discourses align with Deleuze and Guattari’s capitalist, territorial, statist, and nomadic social formations, respectively. The social forms exist in reciprocal relationship to and are the aggregates of concrete assemblages. This paper outlines how CDS scholarship can be connected conceptually and methodologically through this four discourse framework and the relationship between discourse, social form, and concrete assemblage. This coherence and Deleuze and Guattari’s approach to identifying and harnessing opportunities for change can be used to amplify the CDS agenda of challenging data power asymmetries and creating more widely valued data assemblages

    Redox cycling by catechol metabolites of endogenous estrogens as potential contributors to the initiation of breast cancer

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    Human idiopathic post-menopausal mammary adenocarcinoma is a tumor of breast epithelial tissue with a high incidence in women. The etiology of this disease stems from both genetic and environmental factors. A major environmental component thought to be important in the development of breast cancer is estrogen exposure; indeed at least one environmental estrogen is known to have tumorigenic properties. Several studies have attempted to characterize the role of exogenous estrogens in initiating breast cancer; however little work has been done using endogenous human estrogens. The present studies investigated a mechanism by which endogenous estrogens may contribute to idiopathic breast tumor formation. In this mechanism, endogenous estrogens are first metabolized by cytochrome P450s to catechol metabolites. Catechols are known to be reactive and can generate highly toxic and mutagenic reactive oxygen species (ROS) by redox cycling. We have shown that the flavoenzymes NADH-cytochrome b5 reductase and NADPH-cytochrome P450 reductase can mediate redox cycling of catechol estrogen metabolites and generate hydrogen peroxide, superoxide anion, and, under conditions favorable for Fenton chemistry, hydroxyl radicals. Moreover, we show that this process can damage DNA causing strand breakage and nucleotide base oxidation. We also demonstrated that redox cycling by catechol metabolites of endogenous estrogens can occur in breast epithelial cells. Cell lysates from three human mammary epithelial cell lines, MCF-7 (estrogen receptor alpha positive, tumorigenic), MDA-MB-231 (estrogen receptor alpha negative, tumorigenic), and MCF-10A (estrogen receptor alpha negative, non-tumorigenic), were found to redox cycle catechol estrogens and generate ROS. Additionally, these metabolites were found to stimulate hydrogen peroxide release by intact cells as measured using an extracellular electrochemical microsensor. In all cases, the three cell lines were found to be equally active in mediating redox cycling and generating ROS. These data indicate that redox cycling can occur in breast epithelial cells; however, ROS production appears to be independent of either estrogen receptor status or tumorigenic stage. Therefore, catechol estrogen metabolite redox cycling must be a constitutive property of the breast epithelial cells and is not acquired during breast tumor development. Because we can measure release of hydrogen peroxide by intact breast epithelial cells by catechol estrogens, redox cycling must be significant enough to overwhelm protective cellular antioxidant defense systems. Taken together, these data indicate that endogenous estrogen metabolism to catechols and subsequent flavoenzymemediated redox cycling and generation of ROS may contribute to breast tumor development.Ph.D.Includes bibliographical referencesIncludes vitaby Karma Claire Fussel

    An analysis of the stated problems of a selected group of adults enrolled in a community education program as related to development of curriculum, 1978

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    Purpose of the Study: The purpose of this study was to examine the personal dimension, to determine what impact, if any, a community school program tailored to identification of personal problems and examination of ways to reduce or alleviate them had on a group of subjects involved in such an individualized program. Hypothesis: In order to satisfy the purpose of the study the following null hypothesis was tested: There is no significant difference between the number of personal problems identified by a group of adults involved in a community school program before and after training. Method of Research: The method of research used in this study was experimental design, employing the Single Group Method (one group, two different test periods). The subjects were given a pre-test and after one year interval, they were given a post-test. The High School Fundamentals Evaluation Test, Form D, was given to establish a measure of capability of the subjects on experience and educational achievement. The subjects were also assessed on age, sex, race, marital status, occupation, and the number of children. The Mooney Problem: Check List, Form A was given to collect the data required to fulfill the purposes of this study. Findings: The summary of the specific findings in this study can be stated that, there were significant differences on the variables and stated problems (reduction, alleviation, and prevention), between the initial test period, and the final test period. There were also significant differences across the demographic groups on each of the variables. Finally, there was a significant difference between the initial and final test results on each specific variable and demographic group. Therefore, the null hypothesis was rejected because of the above findings. Conclusions: The summary of the findings in this study revealed that the community school program had a positive impact on the subjects in this study. The program had a positive impact on all variables, had a greater impact on some variables and different demographic groups. The requirement that the hypothesis be rejected revealed that the community school program had a positive impact on the subjects in this study. Implications: The findings and conclusions of this study permit some implications to be drawn. First, a program of this type is beneficial to each demographic group that participated in this study. Second, a community school program shows enough evidence to warrant its organization, support, and implementation with the regular K-12 program where the kind of problems studied in this study exist. And finally, the conclusion of a positive impact indicates the possibility that programs of this type are beneficial to the education process with other group of citizens. Recognizing the limitations of the study (the small sample, the small staff, limited financial resources, etc.), the strong evidence of positive impact warrants at least a tentative commitment of the school system to expand such programs as part of its regular offerings. Recommendations: In summarizing the findings, conclusions, and implications emerging from this study, it is fitting to call for further research with larger populations to further verify the findings. In summarizing the findings, conclusions, and implications emerging from this study, it is fitting for the local, state, and national education agencies to examine the feasibility of initiating more community education programs on a local, state, and national basis. In summarizing the findings, conclusions, and implications emerging from this study, it is fitting for teacher/administrator preparation institutions to expand their offerings so that adequate resource personnel are available to provide the services needed to implement community education programs

    The Transition to Adulthood in Aging Societies

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    Population aging and the delay in family formation that are occurring in industrialized countries are intimately related. Young adults are spending more of their early twenties attending school and focusing on employment, and they are postponing marriage and childbearing until their late twenties and early thirties. In sum, they are having fewer children later in life, and in doing so, they contribute to the aging of the population. Some argue that population aging results in lower public and private investments in children and greater public expenditures on the elderly. In this article, the author reviews evidence for this argument and concludes that population aging does not necessarily result in lesser investment in children and youth. Instead, our new demographic condition demands a renegotiation of the public intergenerational contract between age groups. </jats:p

    Bibliography of Nebraska Geology 1843-1976

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    This book is a bibliography of research conducted on Nebraska geology, spanning a period of 133 years. Includes 2,008 bibliographic entries, an author index, and a Key-Word-in-Context (KWIC) index
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