1,721,533 research outputs found
Estudios fermentativos en cepas pertenecientes al género Bacillus
No full textFil: Castro, Guillermo Raúl. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
Estudios fermentativos en cepas pertenecientes al género Bacillus
Full text linkFil: Castro, Guillermo Raúl. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
Nanobiocatalyst for drug delivery
No full textSince the half of the last century, the range of biocatalytic applications has been extended to almost every technological field. Particularly, biomedicine is one of the most auspicious fields for the application of enzymes since the origins of many pathologies are now analyzed and understood at the molecular level. The development of nanotechnology has provided the opportunity to study and understand the interaction of molecules at atom, group, and molecular levels, allowing us to stabilize enzymes by tailoring the interactions with the other macromolecules and the environment. There are many potential roles of the therapeutic use of enzymes such as part of restorative therapies to treat genetic disorders, as a prodrug activator, and as an assistant tool for drug kinetic controlled release from matrices. However, enzymes are very sensitive to environmental factors that could limit their applications. In the present chapter, some of the commonly reported strategies to develop drug delivery systems containing nanobiocatalysts are analyzed.Fil: Rivero Berti, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; ArgentinaFil: Castro, Guillermo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; Argentin
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Bionanoparticles, a green nanochemistry approach
Full text linkBackground: In the past decade, considerable attention has been paid for the development of novel
strategies for the synthesis of different kind of nano-objects. Most of the current strategies are usually working by the use physical or chemical principles to develop a myriad of nano-objects with multiple applications. Main fields of nanotechnology applications range from catalysis, micro- and nanoelectronics (semiconductors, single electrons transistors), non-linear optic devices, photoelectrochemistry to biomedicine, diagnostics, foods and environment, chemical analysis and others. Results: Two main avenues for nanoparticles synthesis: cell-free extract and cell cultivation have been reported. The state of art of both biotechnological approaches for different type nanoparticles are reviewed in this work. Conclusions: Nanotechnology is a revolutionary field just at its onset, the trend in the next decades being its integration with the green chemistry approach. Several strategies involving exhaustive strain selection, cultivation modes, recombinant gene expression, metabolic engineering, protein re-design and re-engineering, and predictive modeling will allow to create nanobioreactors, a new nanobiotechnology arena with a high potential impact in many fields.Fil: Cauerhff, Ana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología Aplicada. Laboratorio de Nanobiomateriales; Argentina;Fil: Castro, Guillermo Raul. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología Aplicada. Laboratorio de Nanobiomateriales; Argentina
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Novel technologies for the encapsulation of bioactive food compounds
No full textRecent advances in nanoscience and nanotechnologies offer a revolutionary approach to the development of novel and healthier foods. Nano-technological and micro-technological carriers based on biomolecules may be tailored in order to deliver molecules, e.g., drugs, nutraceuticals and others, to any organ and tissue in the body. New micro- and nano-biocarriers based on food-grade polysaccharides, proteins, lipids and their blends, coacervates and also hybrid inorganic-biological molecules provide novel platforms to enhance the bioavailability, stability and delivery efficiency of bioactive molecules in the body.Fil: Santiago, Liliana Gabriela. Universidad Nacional del Litoral. Facultad de Ingeniería Química; ArgentinaFil: Castro, Guillermo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; Argentin
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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