155,218 research outputs found
Letter by Castioni et al regarding article, "general anesthesia versus conscious sedation and local anesthesia during thrombectomy for acute ischemic stroke"
No full text
A new device for monitoring respiratory rate in spontaneously breathing patients submitted to i.v.anaesthesia
No full textINCEPT. Studio Multicentrico Italiano sull’INfarto CErebrale Post-Traumatico. Analisi preliminare.
No full textLa microalbuminuria è un fattore di rischio indipendente nei diabetici di tipo II (NIDDM)
No full textANALISI DELLE TENDENZE DI LUNGO TERMINE NEL REGIME DEGLI AFFLUSSI METEORICI E DEI DEFLUSSI DELL’ADDA A LECCO (1845-2014)
No full textLa consultazione di dati di archivio, poco conosciuti, relativi all’idrometro del Fortilizio di Lecco ha permesso la ricostruzione dei livelli idrometrici e dei deflussi giornalieri dall’incile del Lago di Como dal 1845 al 2014. Analogamente sono stati stimati gli afflussi meteorici mensili nel medesimo periodo rendendo quindi possibile un confronto tra le tendenze climatiche di lungo termine che mostrano, applicando i test statistici di Mann-Kendall, Spearman e Theil-Sen, una diminuzione degli afflussi meteorici e, in misura più marcata, dei deflussi. La disponibilità di una delle serie idrometriche e meteorologiche tra le più lunghe disponibili per i bacini italiani permetterà una analisi delle possibili cause di natura climatica e/o antropica delle variazioni
del regime dei deflussi
Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity
No full textThe extracellular matrix (ECM) contributes to the biological and clinical heterogeneity of breast cancer, and different prognostic groups can be identified according to specific ECM signatures. In high-grade, but not low-grade, tumors, an ECM signature characterized by high SPARC expression (ECM3) identifies tumors with increased epithelial-to-mesenchymal transition (EMT), reduced treatment response, and poor prognosis. To better understand how this ECM3 signature is contributing to tumorigenesis, we expressed SPARC in isogenic cell lines and found that SPARC overexpression in tumor cells reduces their growth rate and induces EMT. SPARC expression also results in the formation of a highly immunosuppressive microenvironment, composed by infiltrating T regulatory cells, mast cells, and myeloid-derived suppressor cells (MDSCs). The ability of SPARC to induce EMT depended on the localization and suppressive function of myeloid cells, and inhibition of the suppressive function MDSCs by administration of aminobisphosphonates could revert EMT, rendering SPARC-overexpressing tumor cells sensitive to Doxil. We conclude that that SPARC is regulating the interplay between MDSCs and the ECM to drive the induction of EMT in tumor cells
O. A. C. Review Volume XLVI Issue 5, February 1934
No full textThe focus of this issue is the preparation for College Royal and recognizing its tenth anniversary. This month's agricultural article is a report from the Dominion Parasite Laboratory on the biological control of pests. Other articles provide an account of the activities of a stage manager and the development of the field of home economics at Macdonald College in Quebec. Campus news addresses the success of the 1934 Conversazione, the commemorating of the sixtieth anniversary of the founding of O. A. C., the attendance at the Canadian Author Lecture, and the successful productions of "The Apple Cart" and "Iolanthe". The Macdonald Institute column comments on the Conversat and women's athletics activities in basketball and the rifle club. The Alumni Record supplies alumni updates.EditorialTen Years of the RoyalRamblings on the RoyalBlame it on the stage managerBiological control of insect pests in CanadaNot for girls onlyCollege lifeLiterary sectionO. A. C. sportsfolioAlumni recordMacdonald newsLetters to the editoradvertisin
O. A. C. Review Volume XXXVI Issue 12, August 1924
No full textThis slim summer issue contains the address given by the agricultural section of the British Association for the Advancement of Science, and a report on the visit of this association to the O. A. C. Other articles include instructions on increasing strawberry production and a biography of the author John Masefield. The editorial comments on Rhodes Scholars. The Alumni column provides an update of alumni activities. This issue does not contain a Macdonald column.JoyPresent-day problems in crop productionAfter the strawberry harvestJohn MasefieldVisit of the Agricultural Section of the British Association for the Advancement of ScienceEditorialCollege lifeAlumniadvertisin
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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