862 research outputs found

    Dealing with a cluster of large centralized municipal wastewater treatment plants: A case study

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    The article deals with a cluster of large centralized municipal wastewater treatment plants (LCMWWTPs) assessing the main economic, energy, environmental and management aspects. With reference to the case study of the Regi Lagni system (Southern Italy), composed of five WWTPs for an overall effective population of 2,235,800 inhabitants the study focused first on the multi-disciplinary characterization of the system investigated and then on potential future upgrading options, identifying the best suitable solution. For the scope, several indicators such as running costs, energy consumptions, Greenhouse Gas Emissions (GHG), waste for landfilling and two scenarios were defined. The first scenario focused on the role of anaerobic digestion while the dewatered sludge was sent to landfill. The second scenario implemented the same operations of the previous one although the construction of a thermal treatment plant for the dewatered sludge was also planned. Results showed how LCMWWTPs could be characterised by low resilience; the upgrading of plants to comply with the increasingly stringent legal limits was difficult, especially where works were carried out to ensure continuity of operation. Multi-criteria analysis allowed the cluster system based on anaerobic digestion to be the best solution from an economic, energy and environmental point of view

    Corrado Cagli. Transatlantic bridges, 1938-1947

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    In the 1930s the young Italian artist, Corrado Cagli was a rising star of the Scuola Romana, supported by the Fascist regime despite being both Jewish and a homosexual. Following the Racial Laws, he fled first to Paris, and then to the USA, where he remained until 1947. Raffaele Bedarida’s new book, Corrado Cagli – La pittura, l’esilio, l’America (1938-1947) Donzelli Editore, 2018 (soon to be translated into English by CPL Editions), focuses on Cagli’s American exile. While examining Cagli in the context of the artistic and intellectual migration from Europe to the US, Bedarida provides valuable new insight into the specific plight of this Italian Jewish artist, once championed by Fascism and into the complexities of the use of art for cultural diplomacy. The author combines biography, cultural history, and critical analysis in exploring a decisive period in the life and work of a painter whose complex personality and non-signature style, defy classifications. The book also provides thought-provoking and nuanced arguments on the ideologically based ostracism that Cagli encountered upon returning to Italy in the immediate aftermath of the war. Because of his past as a former regime-endorsed artist, his recent American success, his participation in the liberation of Europe from Nazi-Fascism with the American army, and Jewish exile, Cagli simply did not fit into any of the faction of Italy’s post-war heated cultural disputes. Based on extensive original research and written with brio, Bedarida’s book is an essential contribution to a growing field of studies that examine how, by welcoming artist and intellectuals in flight from Nazi-Fascism, the United States had been given what Will Norman has called “custodianship for a civilization.

    Proceedings of the LREC 2020 workshop on Resources and Techniques for User and Author Profiling in Abusive Language (ResT-UP 2020)

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    This volume documents the Proceedings of the 1st Workshop on Resources and Techniques for User and Author Profiling in Abusive Language (ResT-UP), held online on 12 May 2020 as part of the LREC 2020 conference (International Conference on Language Resources and Evaluation). The workshop aimed at bringing together researchers and scholars working on author profiling and automatic detection of abusive language on the Web, e.g., cyberbullying or hate speech, with a twofold objective: improving the existing LRs, e.g., datasets, corpora, lexicons, and sharing ideas on stylometry techniques and features needed for profile information extraction and classification. ResT-UP targeted Profiling scholars and research groups, experts in Statistic and Stylistic Analysis of texts as well as computational linguists who investigate author profile and personality both in short texts (social media posts, blog texts and email) and in long texts (such as pamphlets, (fake) news and political documents). ReST-UP represented an opportunity to share profiling experiments with the scientific community and to show automatic detection techniques of abusive language on the Web. Despite the cancellation of LREC 2020 due to the COVID-19 international emergency, ResT-UP was organized online on Microsoft Teams on May 12th 2020 and the programme included three oral presentations and featured an invited talk by Paolo Rosso. ResT-UP was attended by about fifty representatives of academic and industrial organisations

    miRNAs’ Cross-Involvement in Skin Allergies: A New Horizon for the Pathogenesis, Diagnosis and Therapy of Atopic Dermatitis, Allergic Contact Dermatitis and Chronic Spontaneous Urticaria

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    Skin inflammation is a common underlying feature of atopic dermatitis, allergic contact dermatitis and chronic spontaneous urticaria. The pathogenetic mechanisms have not been fully elucidated. The purpose of this study was to examine whether miRNA, by regulating inflammatory mechanisms through the modulation of innate and adaptive immune responses, could play a major role in the pathogenesis of these skin conditions. We conducted a narrative review using the Pubmed and Embase scientific databases and search engines to find the most relevant miRNAs related to the pathophysiology, severity and prognosis of skin conditions. The studies show that miRNAs are involved in the pathogenesis and regulation of atopic dermatitis and can reveal an atopic predisposition or indicate disease severity. In chronic spontaneous urticaria, different miRNAs which are over-expressed during urticaria exacerbations not only play a role in the possible response to therapy or remission, but also serve as a marker of chronic autoimmune urticaria and indicate associations with other autoimmune diseases. In allergic contact dermatitis, miRNAs are upregulated in inflammatory lesions and expressed during the sensitization phase of allergic response. Several miRNAs have been identified as potential biomarkers of these chronic skin conditions, but they are also possible therapeutic targets

    Inhibitors derived from wheat straw hydrolysate can affect the production of succinic acid by Actinobacillus succinogenes

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    Lignocellulosic biomasses are promising source of fermentative sugars for the production of succinic acid. The lignocellulosic matrix must be pretreated to make the sugars available for the fermentation, but the most tested operative conditions can generate inhibitors as acetic acid, furans, phenolic compounds. Inhibitors remained an obstacle for the implementation of succinic acid production starting from recalcitrant biomasses as wheat straw. Batch tests were performed at two starting concentrations of strain, sugars (glucose, glucose and xylose) and inhibitors (acetic acid and furfural) by comparing the fermentation in standard broth medium and hydrolysate. Notwithstanding the presence of acetic acid (52.5 mg/L) and furfural (15 mg/L), succinic acid was obtained at 9*10−2 ± 7*10−3 g/L by starting from wheat straw hydrolysate that contained glucose (1.1 g/L), xylose (0.4 g/L) and without additional nitrogen source. Therefore, the study highlighted that a more concentrated inoculum was able to reduce the synergistic effect of inhibitors at their highest concentrations. The results obtained may contribute to improve succinic acid production from the biomasses that have been under-exploited but abundantly available, as wheat straw, for which solutions must be found to solve the problem of inhibitors production or to mitigate its effect on the fermentation process
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