35,459 research outputs found

    Ledger page, Thomas L. Darden in Account with T. J. Carver, 1879

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    This handwritten ledger page accounts purchases made by Thomas L. Darden from T. J. Carver from March to December 1879. The total due in December is recorded as $100.62.https://scholarsjunction.msstate.edu/mss-darden-papers/1402/thumbnail.jp

    U.S. President Barack Obama awards posthumously the Medal of Honor to Private First Class Anthony T. Kaho\u2019ohanohano and Private First Class Henry Svehla for conspicuous gallantry in the Korean War

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    During a ceremony at the White House, President Barack Obama describes the actions of Medal of Honor recipients Private First Class Anthony T. Kaho\u2019ohanohano, U.S. Army, and Private First Class Henry Svehla, U.S. Army, for conspicuous gallantry. Both men were killed in action during the Korean War. An unidentified military aide reads the official Congressional citation as the President presents the medals to family members in turn. U.S. Army Major General Chaplain Douglas L. Carver, delivers the invocation and the benediction

    Letter, Thomas J. Carver to Thomas L. Darden, March 6, 1884

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    This handwritten letter, dated March 6, 1884, is written from Thomas J. Carver, General Manager of the Southwestern Co-Operative Association to Thomas L. Darden informing Darden that he has shipped his order to Fayette, Mississippi. The letter goes on to discuss one of Darden\u27s tenants who owes both Carver and Darden money. The letter is written on Office of Thos. J. Carver letterhead. An envelope addressed to Capt. T. L. Darden and postmarked New Orleans.https://scholarsjunction.msstate.edu/mss-darden-papers/1333/thumbnail.jp

    Single- and Multi-carrier Quadrature Amplitude Modulation: Principles and Applications for Personal Communications, WATM and Broadcasting: 2nd

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    Single- and Multi-carrier Quadrature Amplitude Modulation Principles and Applications for Personal Communications, WLANs and Broadcasting L. Hanzo Department of Electronics and Computer Science, University of Southampton, UK W. Webb Motorola, Arlington Heights, USA formerly at Multiple Access Communications Ltd, Southampton, UK T. Keller Ubinetics, Cambridge Technology Centre, Melbourn, UK formerly at Department of Electronics and Computer Science, University of Southampton, UK Motivated by the rapid evolution of wireless communication systems, this expanded second edition provides an overview of most major single- and multi-carrier Quadrature Amplitude Modulation (QAM) techniques commencing with simple QAM schemes for the uninitiated through to complex, rapidly-evolving areas, such as arrangements for wide-band mobile channels. Targeted at the more advanced reader, the multi-carrier modulation based second half of the book presents a research-orientated outlook using a variety of novel QAM-based arrangements. * Features six new chapters dealing with the complexities of multi-carrier modulation which has found applications ranging from Wireless Local Area Networks (WLAN) to Digital Video Broadcasting (DVB) * Provides a rudimentary introduction for readers requiring a background in the field of modulation and radio wave propagation * Discusses classic QAM transmission issues relevant to Gaussian channels * Examines QAM-based transmissions over mobile radio channels * Incorporates QAM-related orthogonal techniques, considers the spectral efficiency of QAM in cellular frequency re-use structures and presents a QAM-based speech communications system design study * Introduces Orthogonal Frequency Division Multiplexing (OFDM) over both Gaussian and wideband fading channels By providing an all-encompassing self-contained treatment of single- and multi- carrier QAM based communications, a wide range of readers including senior undergraduate and postgraduate students, practising engineers and researchers alike will all find the coverage of this book attractive

    Letter from Stephen T. Mather, U.S. National Park Service to Jesse L. Boyce

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    Letter from the Director of the National Park Service, Stephen T. Mather, to Jesse L. Boyce informing him that immediate action is being taken to remove the TNT from the Grand Canyon

    DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire

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    The majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire

    Urban heat island research in Phoenix, Arizona: Theoretical contributions and policy applications

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    abstract: This review investigates the possible reasons and motivations underpinning the large body of work, as well as summarizing specific themes, approaches, and theoretical contributions arising from such study.Corresponding Author: Winston T. L. Chow Arizona State University [email protected]

    Gallic acid interacts with alpha-synuclein to prevent the structural collapse necessary for its aggregation

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    The accumulation of protein aggregates containing amyloid fibrils, with α-synuclein being the main component, is a pathological hallmark of Parkinson's disease (PD). Molecules which prevent the formation of amyloid fibrils or disassociate the toxic aggregates are touted as promising strategies to prevent or treat PD. In the present study, in vitro Thioflavin T fluorescence assays and transmission electron microscopy imaging results showed that gallic acid (GA) potently inhibits the formation of amyloid fibrils by α-synuclein. Ion mobility-mass spectrometry demonstrated that GA stabilises the extended, native structure of α-synuclein, whilst NMR spectroscopy revealed that GA interacts with α-synuclein transiently.Yanqin Liu, John A. Carver, Antonio N. Calabrese, Tara L. Pukal

    Hemin as a generic and potent protein misfolding inhibitor

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    Abstract not availableYanqin Liu, John A. Carver, Lam H. Ho, Abigail K. Elias, Ian F. Musgrave, Tara L. Pukal

    Letter from Carl Hayden to L. L. Ferrall, Postmaster at Grand Canyon

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    Letter from Carl Hayden to L. L. Ferrall on the favorable conditions for creating a national park and the prospect of the United States entering WW I
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