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    MANUAL OF EQUINE PRACTICE

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    Eye diseases in the horse represent a significant component of equine practice. Although fundamental concepts in ophtalmology may be applicable across all species, the horse has some unique characteristics. This offers a challenge to the general practitioner not only diagnostically but also therapeutically. Equine ophtalmic disease, if inadequately treated, can lead to serious sequelae due to poor understood inflammatory and reparative mechanisms in this species. Unfortunately, even the slightest scars in the horse eye t best look poor cosmetically and at worst may preclude the animal from participating in specialized events, such as racing. This emphasizes the role the general practitioner may play in the final outcome of equine ophtalmic disease. Minor scars elsewhere in the body may be inconsequential but in the eye can be disastrous. This section is designed for use by general practitioner and covers the important equine ocular diseases. Acquisition of a good history, detailed ocular and physical examination, use of appropriate diagnostic aids, and sound knowledge and thoroughness are the most important aspects of equine ophtalmology

    L’associazione chetamina-medetomidina vs chetamina-dexmedetomidina nell’anestesia generale in ratti wistar strain sottoposti a craniotomia

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    Anaesthetic protocols for surgical experimental procedures should be accurate for every kind of research and for each species utilized, in order to have a high survival index. In the rat (Rattus norvegicus), to avoid stress to the subject and for ease way of administration, simple intramuscular or endoperitoneal inoculation are often used, where a combination of a dissociative agent with an alfa-2 agonist has shown to be very effective. In a surgical study where craniotomy had to be performed, 42 rats received endoperitoneally an association of ketamine and medetomidine (75 mg/Kg and 0,5 mg/kg respectively) and 36 rats received ketamine and dexmedetomidine (75 mg/Kg and 0,25 mg/Kg). Onset time was significantly shorter (118’’±12’’ vs 246’’±27’’) and duration of anaesthesia longer (363’±43’ vs 303’±38’) in the rats receiving medetomidine compared with the rats receiving dexmedetomidine, showing that also the “L“ enantiomer of medetomidine plays an important anaesthetic role which needs further investigation
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