1,721,132 research outputs found
Phenotyping long COVID
Full text linkPatients who recover from an acute SARS-CoV-2 infection often present with persistent symptoms lasting for months. The cardiopulmonary exercise test profile of those with “long COVID” is suggestive of deconditioning with a tendency to hyperventilation
Personalized exercise prescription as a tool for hypertension management and cardiovascular prevention: Evidence and pending issues
No full textThis editorial refers to `Personalized exercise prescription in the prevention and treatment of arterial hypertension: a Consensus Document from the European Association of Preventive Cardiology (EAPC) and the ESC Council on Hypertension', by H. Hanssen et al. doi:10.1093/eurjpc/zwaa141
Reply to: ‘The hyperdynamic circulatory profile of patients with COVID-19-related acute vascular distress syndrome’
No full textDo Existing Definitions Identify Subgroup Phenotypes or Reflect the Natural History of Heart Failure with Preserved Ejection Fraction?
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Central sleep apnea during continuous positive airway pressure therapy in obstructive sleep apnea patients: From the compliance to adaptation, maladaptation and reflexes
Full text linkThe right side of the circulation in not secondary heart failure with preserved ejection fraction: an elephant in the room?
No full textPulmonary arterial hypertension associated with a von Hippel-Lindau gene mutation
No full textPulmonary arterial hypertension (PAH) is a rare dyspnea-fatigue syndrome caused by increased pulmonary vascular resistance (PVR) and eventual right heart failure. Several conditions and some definite gene mutations can be associated with PAH. A small number of patients with a diagnosis of pulmonary hypertension (PH) in relation to genes mutations associated with congenital erythrocytosis, and in particular with von Hippel-Lindau (VHL) gene mutation, have been reported.
However, these reports only mentioned an increased pulmonary artery pressure (PAP), without reporting complete clinical and hemodynamic data, so whether the patients really suffered from PAH is uncertain
Exercise stress echocardiography of the pulmonary circulation and right ventricular-arterial coupling in healthy adolescents
No full textAims : To explore the effects of age and sex in adolescents vs. young or middle-aged adults on pulmonary vascular function and right ventricular-arterial (RV-PA) coupling as assessed by exercise stress echocardiography. Methods and results : Forty healthy adolescents aged 12-15 years were compared with 40 young adults aged 17-22 years and 40 middle-aged adults aged 30-50 years. Sex distribution was equal in the three groups. All the subjects underwent an exercise stress echocardiography. A pulmonary vascular distensibility coefficient α was determined from multipoint pulmonary vascular pressure-flow relationships. RV-PA coupling was assessed by the tricuspid annular plane systolic excursion (TAPSE) to systolic pulmonary artery pressure (PASP) ratio, who has been previously validated by invasive study. While cardiac index and mean PAP were not different, adolescents compared to young and middle-aged adults, respectively had higher pulmonary vascular distensibility coefficients α (1.60 ± 0.31%/mmHg vs. 1.39 ± 0.29%/mmHg vs. 1.20 ± 0.35%/mmHg, P < 0.00001). Adolescents and young adults compared to middle-aged adults, respectively had higher TAPSE/PASP ratios at rest (1.24 ± 0.18 mm/mmHg and 1.22 ± 0.17 mm/mmHg vs. 1.07 ± 0.18 mm/mmHg, P < 0.008) and during exercise (0.86 ± 0.24, 0.80 ± 0.15 and 0.72 ± 0.15 mm/mmHg, P < 0.04). The TAPSE/PASP ratio decreased with exercise. There were no sex differences in α or TAPSE/PASP. Conclusion : Compared to adults, adolescents present with a sex-independent more distensible pulmonary circulation. Resting and exercise RV-PA coupling is decreased in middle-aged adults
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