1,721,071 research outputs found
The Power of Environment: A Comprehensive Review of the Exposome’s Role in Healthy Aging, Longevity, and Preventive Medicine—Lessons from Blue Zones and Cilento
No full textAging and longevity are shaped by the exposome, a dynamic network of environmental, social, and biological factors. Understanding how these exposures interact with biological mechanisms can inform strategies for healthier aging. Background/Objectives: This review explores the exposome as a dynamic system encompassing both protective and risk factors, with a specific focus on how beneficial environmental exposures, microbiome diversity, lifestyle behaviors, and resilience mechanisms contribute to successful aging. By analyzing high-longevity populations, such as the Blue Zones and Cilento, it aims to identify common determinants of successful aging. Methods: A mixed-method study was conducted, combining a systematic review of the English literature (2003-2024) with a comparative analysis of longevity regions. A structured search was performed in PubMed, Scopus, and Google Scholar using keywords such as "longevity", "Blue Zones", "Cilento", "microbiome", "environmental factors", and related terms. Additionally, qualitative and quantitative analysis were applied to assess key protective factors across different aging models. Results: This study identified key factors contributing to successful aging in longevity hotspots, including sustained exposure to biodiverse natural environments, adherence to Mediterranean or plant-based diet rich in polyphenols and probiotics, regular physical activity, strong social networks, and psychological resilience. A novel aspect of this review is the role of the gut microbiome as a mediator between environmental exposures and immune-metabolic health, influencing inflammation modulation and cellular aging. Despite geographic and cultural differences, case studies reveal a shared pattern of protective factors that collectively enhance lifespan and healthspan. Conclusions: The exposome is a critical determinant of aging trajectories, acting through complex interactions between environmental and biological mechanisms. By integrating insights from high-longevity populations, this mixed-method study proposes a comprehensive framework for optimizing microbiome health, enhancing resilience, and promoting protective environmental exposures. These findings provide a translational perspective to guide future interventions in aging research and global health initiatives
L’uso delle tecniche di amplificazione genica nella ricerca dei microrganismi di interesse igienistico
No full textIndagini sulle conoscenze nutrizionali di operatori sanitari, insegnanti e studenti universitari della Campania.
No full textVariazione della domanda di prestazioni di laboratorio in Campania nel biennio 2000-2001
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Andamento delle malattie sessualmente trasmissibili soggette a obbligo di denuncia in Italia, nella regione Campania e nelle relative province. (1960-1986)
No full textRischio professionale da HBV: andamento triennale dei tassi di siero conversione nel personale parasanitario in formazione
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Differences in health promoting lifestyle profile among students of the University of Salerno according to gender and the age group of study
No full textBackground: The health of female and male university students is an important public health problem in the short, medium and long term because they represent potential professionals of the future, and their lifestyles, their attitudes and their beliefs about health can have a decisive influence on the well-being of the entire population. Despite well documented benefits of health promoting behaviors, many studies have shown that university students exhibit behaviors of unhealthy lifestyle, especially inadequate alimentary behaviour and responsibility for health, which needs further research. The relationship between health indicators and life quality is significantly important in clinical decisions and health policy making and the life quality perspective is a strong stimulus for the individual's decisions and preferences. The aim of this study was to examine gender differences in health-promoting lifestyle among undergraduate students and to analyze changes between the first and second age groups of the study.
Methods: A peer-reviewed and grey literature review of quality of life in undergraduate students was conducted through a
narrative search of MEDLINE and on the website of the major European Observatory on Health Systems and Policies. The search was restricted to papers published in English, German and Italian. Data collection was done through a six-section questionnaire. All data were analyzed with STATA (IC 15 64-bit 2017 version).
Results: A total of 519 students formed the sample. Of this sample 182 as men (35.07%) and 315 as women (60.69%). The age ranged from a minimum of 18 years to a maximum of 35 years. Regarding perceived health by the students the results showed the best average for males of the age group A (77.36%). The statistical test denoted highly significant correlation between health perception and genders (P = 0.0002) and very significant correlation between the age cohort A and B (P = 0.005). HPLPII, PHQ15,
EAT-26 and EQ-5D total scores were calculated mean and median highlighted by a bar chart. Significant gender differences were found in the following subscales: psychosomatic disorders (p= 0.0001), alimentary behaviour (p= 0.0001), quality of life related to health (p= 0.0018). Significant differences between age groups A and B were observed in lifestyle (p= 0.005), alimentary behaviour (p= 0.04), quality of life related to health (p= 0.04).
Conclusion: We hypothesized that there were a gender and age groups differences in health-promoting lifestyle among
undergraduate students. Results from the present study support our hypothesis. The significant findings are that younger male students enjoy better health and quality of life than female students of the same cohort. They have a better view of their life, they look for new challenges and they are changing in a positive way. Data analysis shows that younger male students have a better self-perception of their health status than females of both age groups. In general, aspects of body image, eating behavior and perceived health competence, as well as academic characteristics, were significantly important in evaluating the quality of life in undergraduate students at the University of Salerno
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