1,720,966 research outputs found
L’ecografia intraorale e le sue applicazioni oncologiche
No full textIl carcinoma squamoso del cavo orale (OSCC) è una delle neoplasie più frequenti del distretto testa-collo. La profondità di infiltrazione (depth of invasion, DOI) è stata inclusa come parametro determinante per lo stadio T nell’VIII edizione della classificazione TNM. L’ecografia intraorale (IOUS), grazie all’impiego di sonde ad alta frequenza, si propone come metodica di imaging non invasiva per la valutazione preoperatoria della DOI.
Questo studio descrive la tecnica ecografica, la sonoanatomia dei principali sottositi del carcinoma orale, i reperti patologici e presenta i risultati di un’analisi retrospettiva condotta su 74 pazienti affetti da OSCC. È stato effettuato il confronto tra la DOI misurata ecograficamente (usDOI) e quella istopatologica (pDOI), e, quando disponibile, anche con quella ottenuta tramite risonanza magnetica (mrDOI).
L’ecografia ha mostrato una forte correlazione con la pDOI (r = 0.91), un errore medio estremamente contenuto (0.43 mm), una sensibilità del 100% e una specificità del 76,2% nell’identificazione di DOI ≥3 mm (cut-off per l’indicazione allo svuotamento linfonodale secondo le linee guida), con una performance superiore rispetto alla risonanza magnetica.
L’accuratezza della metodica è risultata maggiore nei tumori con DOI <10 mm. L’ecografia intraorale può dunque essere considerata uno strumento affidabile e di elevata precisione per la stadiazione preoperatoria dei carcinomi orali, in particolare nelle forme precoci.Oral squamous cell carcinoma (OSCC) is one of the most common malignancies of the head and neck region. Depth of invasion (DOI) was introduced as a defining parameter for T staging in the 8th edition of the TNM classification. Intraoral ultrasound (IOUS), enabled by the use of high-frequency probes, is emerging as a non-invasive imaging modality for the preoperative assessment of DOI.
This study describes the ultrasound technique, the sonoanatomy of the main subsites of oral carcinoma, and relevant pathological findings, and presents the results of a retrospective analysis involving 74 patients with OSCC. DOI measured with IOUS (usDOI) was compared with the histopathological reference standard (pDOI), and, when available, with MRI-derived DOI (mrDOI).
IOUS showed a strong correlation with pDOI (r = 0.91), with a very low mean error (0.43 mm), 100% sensitivity and 76.2% specificity in identifying DOI ≥3 mm (the recommended cut-off for elective neck dissection according to current guidelines), outperforming MRI.
The accuracy of IOUS was higher in tumors with DOI <10 mm. Intraoral ultrasound can therefore be considered a reliable and highly accurate tool for the preoperative staging of oral carcinomas, especially in early-stage lesions
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Imaging assessment of deep neck spaces infections: an anatomical approach
No full textDespite the widespread use of antibiotics, deep neck infections are still a relevant clinical problem and can cause severe and potentially life-threatening complications. Imaging plays a pivotal role into the clinical management of deep neck infections, allowing identification of the source of infections, definition of the precise extension of the disease and early diagnosis of local or distant complications. The complex anatomy of deep neck spaces may hide the actual extent of disease: the knowledge of neck anatomy enables radiologists to rapidly evaluate expected routes of spread of infections and to effectively communicate crucial information to surgeons. Computed Tomography is the most used imaging modality for assessing primary site of infection, extent of disease and local complications. Magnetic resonance imaging may be used as a second level imaging modality for individuating intracranial or spinal complications. The present work aims to review the imaging of deep neck spaces infections, focusing on relevant anatomy and clinical scenarios, underlining practical teaching points for each of them. Familiarity with deep neck spaces anatomy and knowledge of most common routes of spread of infections allow the radiologist to make a prompt diagnosis and to look for early signs of potential complications
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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