727 research outputs found
Investigation of Microbial Consortia: From Fundamental to Applied Results, From Established to Novel Production Systems
Soil microbiology has long been a rich source of novel scientific discoveries and continues to be a key contributor to industrial applications. In this regard, fungi have played multifaceted roles, from promoting plant growth to serving as prolific producers of antimicrobial compounds. Despite significant advances, the full potential of fungal–plant interactions remains underexplored, particularly in the case of the aromatic and medicinal plants such as Lavandula, and the microfungal communities associated with its root system. In this work, we demonstrated that the characterization of microfungal community in association with Lavandula led not only to taxonomical advancements by expanding established fungal phylogenies, but also to the discovery and characterization of novel antimicrobial compounds such as antifungal proteins (AFPs). A comprehensive methodological pipeline was employed, beginning with fungal isolation, morpho-molecular species-level identification, biodiversity assessment, and taxonomic classification. These were followed by protein production and purification, biochemical and structural characterization, and genome engineering techniques. This integrative framework enabled the translation of basic mycological discoveries into biotechnologically relevant results.
Ecological analyses revealed that climate ecosystems, rather than plant species identity, were the predominant determinants affecting microfungal community composition. Lavander-associated fungal communities displayed strong site-specific variability, with alpha diversity gradually declining from Mediterranean to continental climates while beta diversity revealed complex patterns influenced by agricultural practices, highlighting the need for further research to harness their ecological and agricultural potential. Additionally, two novel fungal species belonging to the genera Rasamsonia and Talaromyces were identified and described for the first time. While the thermophilic Rasamsonia lemurum shares the genus' typical heat tolerance but exhibits rare globose conidia, Talaromyces montemartinii displays unusual thermotolerance and reduced sporulation, together highlighting how thermal adaptation and morphological divergence shape fungal biodiversity. Moreover, we reported the identification, production, and functional characterization of AfAfpC, a novel AFP from the Lavandula soil isolate Aspergillus fischeri. AfAfpC exhibited moderate-to-strong inhibitory activity against filamentous fungi, despite its near-neutral isoelectric point. CRISPR-Cas9-mediated deletion of the afafpC gene revealed that it is dispensable for growth and development. These findings enhance our understanding of AFP diversity and establish A. fischeri as a promising platform for the development of sustainable antifungal applications. Finally, the incorporation of the developed know-how was designed and started to be implemented in an innovative project uniting aquaculture systems with Artificial Intelligence. Potential future research directions might see other, novel species descriptions deriving from similar working guidelines, as well as new antimicrobial compounds discovered and investigated in their biotechnological potential
Visas e altre poesie. Con documenti e testimonianze e il CD Visas per Vittorio Reta di Stefano Scodanibbio
Il libro comprende l'opera poetica integrale di Vittorio Reta: oltre a «Visas», infatti, apparso per Feltrinelli nel 1976, sono qui pubblicate per la prima volta più di sessanta poesie inedite, diverse per epoca e per connotazioni stilistiche. I testi sono introdotti da un ampio saggio storico-letterario ed ermeneutico e corredati da una nota filologica. Il libro offre anche una inedita documentazione fotografica dell'autore e un cd allegato con l'opera composta da Stefano Scodanibbio «Visas per Vittorio Reta», nata da una suggestione cui non è estraneo Edoardo Sanguineti.The book includes the integral poetic work of Vittorio Reta: in addition to «Visas», in fact, appeared for Feltrinelli in 1976, here are published for the first time more than sixty poems unpublished before, different by age and stylistic connotations. The texts are introduced by a large historical-literary and hermeneutic essay and accompanied by a philological note. The book also offers an unpublished photographic documentation of the author and a CD with the opera composed by Stefano Scodanibbio «Visas for Vittorio Reta», born from a suggestion received probably by Edoardo Sanguineti
Vittorio Alfieri's Antigone : a translation
Orientador: Suzi Frankl SperberDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da LinguagemResumo: este trabalho consiste numa tradução da peça Antigone, do tragediógrafo italiano Vittorio Alfieri, escrita em 1776 em Florença, Itália. Esta tragédia revela inquietações artísticas e particularidades linguísticas que refletem o período que antecede o Risorgimento, tanto no âmbito político quanto no que se refere à cultura e ao idioma italiano. A presente dissertação apresenta também um perfil biográfico de Vittorio Alfieri, autor até o momento pouco conhecido no Brasil, a partir de estudo de sua autobiografia e de estudos publicados na Itália sobre sua obra e seu envolvimento com movimentos políticos que culminaram na Revolução FrancesaAbstract: this work consists on a translation of the play Antigone, by the Italian tragedy writer Vittorio Alfieri. The play was written in 1776 in Florence, Italy. This tragedy reveals artistic concerns and linguistic particularities that reflect the period of time that precedes the Risorgimento, both in a political extent as in where the Italian culture and language is concerned. The present dissertation presents also a biographic profile of Vittorio Alfieri, author until this moment little known in Brazil, based on the study of his autobiography and texts published in Italy about the author's work and involvement in political movements that led to the French RevolutionMestradoTeoria e Critica LiterariaMestra em Teoria e História Literári
Scritti di Vittorio Franchetti Pardo sulla città e sull’architettura
The anthology collects published and unpublished writings by Vittorio Franchetti Pardo. The first volume is dedicated to the history of the city, with particular emphasis on the medieval period. The author dwells in detail on Florence, but also on the Frederick and Aragonese period which, in southern Italy, leaves significant evidence in the development of cities and the territory.L'antologia raccoglie scritti editi e non di Vittorio Franchetti Pardo. Il primo volume è dedicato alla storia della città, con particolare enfasi nel periodo medievale. L'autore si sofferma dettagliatamente su Firenze, ma anche sul periodo federiciano e aragonese che, nel meridione di Italia, lascia testimonianze significative nello sviluppo delle città
Giuseppe Mengoni. Architect of Milan’s Galleria Vittorio Emanuele II. (1829–1877)
The essay deals with Giuseppe Mengoni, author of the Galleria Vittorio Emanuale II in Milan, focusing on its innovative features in both urban design and technological solutions
Bank Recovery and Resolution: An Italian Point of View
The author examines the main legal aspects of the Single Resolution Mechanism as provided by the Directive no. 59 of 15 May 2014 and the Regulation no. 806 of 15 July 2014. After finding a definition tailored on the term “resolution”, the author pays particular attention to some important aspects as: recovery plan, preventive measures, early intervention measures and the resolution. As regards the latter one, the author examines especially all resolution instruments like the “sale of business tool”, the “bridge institution tool”, the “asset separation tool” and the “bail-in tool” noting in particular the effects of the application of those tools on stakeholders and their impact on the Italian banking legal system. Finally, considering the drastic nature of the last tool, the author put in the light an important doctrinal debate, i.e. the compatibility of that tool (and more generally the provisions of the Directive) with the article 47 of the Italian Constitution
Fungal Arsenic Tolerance and Bioaccumulation: Local Strains from Polluted Water vs. Allochthonous Strains
The paper deals with the possible use of fungi to decontaminate polluted waters. Specifically, the focus is the selection of the most promising fungal strain capable of bioaccumulating arsenic, which is a globally widespread environmental contaminant. To this aim, allochthonous fungal strains from the ColD UNIGE JRU MIRRI strains collection were selected. Their capability to survive and accumulate this kind of pollutant was evaluated and compared with that of an autochthonous fungi set directly isolated from the arsenic polluted water. A preliminary screening at various concentrations of arsenic (0, 200, 400, 800, 1600 μg L−1) revealed that the best performing strains were Aspergillus niger and Penicillium expansum among the autochthonous strains and Aspergillus niger and Penicillium expansum among the allochthonous strains. Moreover, all the strains were subjected to bioaccumulation tests at a 1600 μg L−1 concentration. Local and allochthonous fungal strains showed different behaviors: the allochthonous strains grew rapidly and in a sustained way but without expressing any bioaccumulation activity. On the contrary, the indigenous fungi, despite a moderate growth, showed a good bioaccumulation capacity (in particular, Aspergillus niger). The results highlight the importance of employing native strains isolated from contaminated matrices to make a mycoremediation protocol more efficient
I servizi di pagamento
The paper gives a critically overview of the legal framework for
payment services focusing on the directive 2007/64/EC, the
legislative decree n. 11/2010 and the Bank of Italy’s regulations.
Provided the state of payment instruments, the Author drives its
attention to the payment account as a framework contract for the
provision of payment services as well as to the duties and rights
of the professional providers and the users
A comparison of bone-patellar tendon-bone and bone-hamstring tendon-bone autografts for anterior cruciate ligament reconstruction
Una nuova architettura europea di vigilanza finanziaria?
This paper examines the European supervisory architecture on credit, securities
and insurance markets. The author carries out some considerations about the economic policy of the European financial supervisory system, such it released by the European Commission Proposal (COM/2017 536 final). The author supports, the
need to strengthen investor protection, by assigning (in the medium to long term)
this task to the European Securities and Markets Authority
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