1,720,977 research outputs found
Physical activity and exercise as key factors in successful aging
Aging is associated with several changes in body composition and metabolism, including sarcopenia, sarcopenic obesity and decrease in bone mass; aerobic capacity, muscle mass and strength tend to decline progressively. These changes have considerable impact on the ability to perform daily activities, especially when associated with chronic diseases, such as type 2 diabetes, cardio-vascular disease and dyslipidemia, as well as geriatric syndromes, like mobility impairment, falls and frailty. Scientific research has shown that physical activity and exercise can slow the physiological aging clock. Particularly, active elderly people seem to age “successfully” compared to sedentary ones. The aim of our work is to review evidence-based recommendations for physical activity, exercise and diet that would help to preserve muscle mass and strength, and to reduce the gain of fat mass in older adults. Increasing levels of physical activity, in particular resistance training mixed with aerobic exercise, and adequate protein nutrition intake should be an integral component in the prevention and treatment of sarcopenia, sarcopenic obesity and metabolic syndrome in elderly subjects
Il consumatore italiano
Il saggio ricostruisce le principali tappe della trasformazione dei consumi alimentari in Italia dal momento dell'unificazione della penisola ad oggi. Vengono sviluppati i seguenti aspetti: i consumi alimentari nelle campagne italiane nel lungo Ottocento, con particolare attenzione alle loro differenze regionali; l'andamento dei consumi durante le due guerre mondiali e nel periodo dell'autarchia; la lenta ricostruzione del dopoguerra e gli effetti dell'industrializzazione del settore alimentare nel consumo dei cibi, con particolare riguardo al processo di urbanizzazione degli anni Cinquanta e Sessanta; nuove forme di distribuzione e di marketing del cibo, con particolare riguardo al rapporto tra l'affermazione del sistema dei marchi e la pubblicità televisiva; il mutamento degli stili di consumo a partire dagli anni Ottanta con la trasformazione dei tempi del lavoro e del consumo, la differenziazione dei gusti, la proliferazione delle opportunità di consumo extra-domestico
Serum Malondialdehyde Levels in Hypertensive Patients: A Non-invasive Marker of Oxidative Stress. A Systematic Review and Meta-analysis.
Introduction: Previous analyses have reported a higher malondialdehyde (MDA) serum level in hypertensive patients (HTs) compared to normotensive subjects (NTs).
Aim: We performed a systematic review and meta-analysis of these studies to offer a comprehensive information on this issue.
Methods: The PubMed, EMBASE and Web of Science databases were analysed to locate English-language articles published from January 1, 2000 up to January 1 2021. Studies were identified using the following MeSH terms: "Malondialdehyde" AND "Arterial hypertension". The difference of MDA serum levels between HTs and NTs was expressed as standardized mean difference (SMD) with 95% CI using a random-effect model.
Results: A total of of 4102 patients (2158 HTs and 1944 NTs, mean age 52.7 and 48.0 years, respectively) were included in 17 studies. Pooled mean MDA serum levels in HTs and NTs were 4.91 [standard error (SE): 0.34, 95% CI 4.23-5.59)] and 3.43 [SE 0.15, 95% CI 3.18-3.78] nmol/L, respectively. The SMD between HTs and NTs was 3.23 nmol/L (95% CI 2.54-3.92; Z-score for overall effect: 9.17, p < 0.0001, I2 = 98.6%). Egger's test resulted significant at p = 0.009 while Begg's test was not, p = 0.11. Subsequent adjustment via the trim-and-fill method did not predict a new model (studies trimmed = 0). Meta-regression analysis found no correlations either between SMD and age (p = 0.95) or BMI (p = 0.96) but a significant one considering the latitude of the study site as moderator variable (p = 0.001).
Conclusions: Among patients with HTs, serum MDA appears to have the greatest potential as non-invasive biomarkers of oxidative stress and endothelial dysfunction (ED)
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Sindrome delle apnee ostruttive nei pazienti obesi: effetti sul profilo metabolico e cardiovascolare e risposta a 6 mesi alla terapia comportamentale.
Sindrome delle apnee ostruttive nei pazienti obesi: effetti sul profilo metabolico e cardiovascolare e risposta a 6 mesi alla terapia comportamentale. 30° Congresso Nazionale Società Italiana Studio Aterosclerosi, Roma, 20-22 novembre 2016
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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