1,720,967 research outputs found

    Clinical assessment and management of balance in Parkinson\'s disease

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    Introdução: O comprometimento do equilíbrio na doença de Parkinson (DP) melhora apenas parcialmente com a medicação dopaminérgica. Portanto, intervenções não farmacológicas, como a fisioterapia, são elementos importantes no manejo clínico. Os estímulos externos são frequentemente aplicados para melhorar a marcha, mas seus efeitos no controle do equilíbrio não são claros. Objetivos: (1) Desenvolver um protocolo de avaliação e exercícios de equilíbrio com pistas auditivas rítmicas para melhorar e manter e equilíbrio na DP; (2) realizar um ensaio clínico prospectivo, randomizado e duplo-cego para estudar a eficácia do treinamento de equilíbrio com e sem estímulos auditivos rítmicos. Métodos: Nós selecionamos 201 voluntários por telefone; 154 foram distribuídos aleatoriamente em três grupos: (1) treino de equilíbrio com pistas auditivas rítmicas (treinamento de equilíbrio multimodal); (2) treino de equilíbrio padrão sem pistas auditivas rítmicas; e (3) controle de intervenção envolvendo um programa de educacional sobre DP. O treinamento foi realizado por 5 semanas, duas vezes / semana. O desfecho primário foi a pontuação do Mini-BESTest (MBEST) imediatamente após o período de treinamento. As avaliações foram realizadas por um avaliador único, cego no início do estudo, imediatamente após a intervenção, e após 1 e 6 meses de follow-up. Resultados: Foram incluídos 154 pacientes: treinamento multimodal (n = 56); treinamento padrão (n = 50); controles (n = 48). Grupos eram comparáveis no início do estudo. Diretamente pós intervenção, o treinamento multimodal foi mais eficaz do que o treinamento padrão (p < 0,001). Os pacientes alocados para ambas as intervenções ativas melhoraram em comparação aos controles no MBEST (p < 0,001) para treinamento multimodal e (p < 0,001) para treinamento padrão. As melhorias foram mantidas no acompanhamento de um mês para ambas as intervenções ativas, mas apenas o grupo de treinamento multimodal manteve sua melhora em 6 meses. Conclusão: Tanto o treinamento multimodal quanto o treinamento padrão melhoram o equilíbrio, mas o treinamento multimodal - acrescentando pistas auditivas rítmicas à fisioterapia de rotina - tem efeitos maiores e mais sustentadosBackground: Balance impairment in Parkinson\'s disease (PD) improves only partially with dopaminergic medication. Therefore, non-pharmacological interventions such as physiotherapy are important elements in clinical management. External cues are often applied to improve gait, but their effects on balance control are unclear. Objective: (1) to perform an assessment and exercises protocol with rhythmic cues to improve gait and balance in PD; (2) to performed a prospective, single-blind, randomized clinical trial to study the effectiveness of balance training with and without rhythmical auditory cues. Methods: We screened 201 volunteers by telephone; 154 were assigned randomly into three groups: (1) balance training with rhythmical auditory cues (multimodal balance training); (2) standard balance training without rhythmical auditory cues; and (3) control intervention involving a general education program. Training was performed for 5 weeks, two times/week. Primary outcome was the Mini-BESTest (MBEST) score immediately after the training period. Assessments were performed by a single, blinded assessor at baseline, immediately post intervention, and after one and 6-months follow-up. Treatment effects will be estimated with a linear mixed model, adjusted for MBEST scores and UPDRS at baseline and levodopa equivalent daily dose. Results: 154 patients were included: multimodal training (n=56); standard training (n=50); controls (n=48). Groups were comparable at baseline. Directly post intervention, multimodal training was more effective than standard training (p < 0.001). Patients allocated to both active interventions improved compared to controls (MBEST estimated mean difference versus controls (p < 0.001) for multimodal training and (p < 0.001) for standard training. Improvements were retained at one-month follow-up for both active interventions, but only the multimodal training group maintained its improvement at 6 months. Conclusion: Both multimodal training and standard training improve balance, but multimodal training - adding rhythmical auditory cues to routine physiotherapy - has greater and more sustained effects

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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