1,721,477 research outputs found

    Knowledge transfer in mergers and acquisitions: how frequent acquirers learn to manage the integration process

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    Acquisitions 1 are an effective tool to implement deliberate corporate strategy or the unique occasion to shift towards an emergent one. They can either allow a firm, to adjust its products- markets portfolio, at a speed not achievable through internal development, either provide the ability to gain all the benefits from pooling assets and sharing capabilities, in a way not obtainable through partnerships. From an organisational perspective, acquisitions can either bring into a company those capabilities the organization could not develop internally, either leverage existing capabilities into much more significant situations

    Do Cannabinoids Confer Neuroprotection against Epilepsy? An Overview.

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    Objective: Cannabinoid-based medications provide not only relief for specific symptoms, but also arrest or delay of disease progression in patients with pain, multiple sclerosis, and other conditions. Although they also seem to hold potential as anticonvulsant agents, evidence of their efficacy in epilepsy is supported by several evidences. Method: The data reviewed herein lend support to the notion that the endocannabinoid signalling system plays a key modulation role in the activities subserved by the hippocampus, which is directly or indirectly affected in epilepsy patients. Conclusion: The notion is supported by a variety of anatomical, electrophysiological, biochemical and pharmacological findings. These data suggest the need for developing novel treatments using compounds that selectively target individual elements of the endocannabinoid signalling system. </jats:sec

    Filtrations of numerically flat Higgs bundles and curve semistable Higgs bundles on Calabi-Yau varieties

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    We consider Higgs bundles satisfying a notion of numerical flatness (H-nflatness) that was introduced in [5; 4], and show that they have Jordan-Hölder filtrations whose quotients are stable, locally free and H-nflat. This is applied to show that curve semistable Higgs bundles on simply connected Calabi-Yau varieties have vanishing discriminant
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