186,500 research outputs found
Endocan as a marker of endothelial dysfunction in hypertension: a systematic review and meta-analysis
No full textHypertension is one of the foremost risk factors for cardiovascular disease and a significant cause of death worldwide. Importantly, endothelial dysfunction (ED) is one of the primary manifestations that may precede the development of hypertension. Endocan is a novel endothelial dysfunction and inflammation biomarker secreted from endothelial cells. Whether endocan may serve as a biomarker of hypertension is currently debated. This systematic review and meta-analysis aimed at linking endocan to ED in hypertensive patients. International databases, including PubMed, Scopus, Embase, and Web of Science, were systematically searched for studies investigating Endocan serum or plasma levels in hypertensive patients and healthy controls. Random effect meta-analysis was performed to calculate the standardized mean difference (SMD) and 95% confidence interval (CI). A total of 20 studies assessing the association between endocan levels and hypertension were included in which 3130 individuals with a mean age of 50.48 ± 8.45 years were assessed. Hypertensive patients presented with higher circulating endocan levels (SMD 0.91, 95% CI 0.44-1.38, p-value < 0.01) compared with healthy controls. Interestingly, our data demonstrated that removing three studies assessing endocan levels in hypertensive patients with different comorbidities or special populations resulted in the same statistically higher endocan levels (SMD 1.16, 95% CI 0.66-1.65, p-value < 0.01). Overall, this systematic review and meta-analysis indicated that in hypertensive patients circulating endocan levels are significantly elevated. Thus, suggesting endocan as an easy-to-use biomarker to detect ED in hypertension. Despite this, more research is warranted to address this potential ability specifically
Dati archeologici e analisi archeometriche di vasetti tipo “San Martino” rinvenuti in Emilia
No full textAnalisi archeometriche petrografiche, mineralogiche e chimiche di ceramiche neolitiche tipo "San Martino" da Vicofertile, Collecchio, Parma via Guido Rossi, Gaione, Razza di Campeine. Le analisi indicano una produzione locale nei diversi siti con materie prime fini e cottura intorno agli 800 gradi
The seismogenic structure of the 2013-2014 Matese seismic sequence, Southern Italy: implication for the geometry of the Apennines active extensional belt
No full textSeismological, geological and geodetic data have been integrated to characterize the seismogenic structure of the late 2013-early 2014 moderate energy (maximum local magnitude M-Lmax = 4.9) seismic sequence that struck the interior of the Matese Massif, part of the Southern Apennines active extensional belt. The sequence, heralded by a M-L = 2.7 foreshock, was characterized by two main shocks with M-L = 4.9 and M-L = 4.2, respectively, which occurred at a depth of similar to 17-18 km. The sequence was confined in the 10-20 km depth range, significantly deeper than the 1997-1998 sequence which occurred fewkm away on the northeastern side of the massif above similar to 15 km depth. The depth distribution of the 2013-14 sequence is almost continuous, albeit a deeper (16-19 km) and a shallower (11-15 km) group of events can be distinguished, the former including the main shocks and the foreshock. The epicentral distribution formed a similar to 10 km long NNW-SSE trending alignment, which almost parallels the surface trace of late Pliocene-Quaternary southwest-dipping normal faults with a poor evidence of current geological and geodetic deformation. We built an upper crustal model profile for the eastern Matese massif through integration of geological data, oil exploration well logs and seismic tomographic images. Projection of hypocentres on the profile suggests that the seismogenic volume falls mostly within the crystalline crust and subordinately within the Mesozoic sedimentary cover of Apulia, the underthrust foreland of the Southern Apennines fold and thrust belt. Geological data and the regional macroseismic field of the sequence suggest that the southwest-dipping nodal plane of the main shocks represents the rupture surface that we refer to here as the Matese fault. The major lithological discontinuity between crystalline and sedimentary rocks of Apulia likely confined upward the rupture extent of the Matese fault. Repeated coseismic failure represented by the deeper group of events in the sequence, activated in a passive fashion the overlying similar to 11-15 km deep section of the upper crustal normal faults. We consider the southwest-dipping Matese fault representative of a poorly known type of seismogenic structures in the Southern Apennines, where extensional seismogenesis and geodetic strain accumulation occur more frequently on NE-dipping, shallower-rooted faults. This is the case of the Boiano Basin fault located on the northern side of the massif, to which the 1997-1998 sequence is related. The close proximity of the two types of seismogenic faults at the Matese Massif is related to the complex crustal architecture generated by the Pliocene-early Pleistocene contractional and transpressional tectonics
Heterotopic bone formation in uncemented total hip prostheses: a retrospective study of predisposing factors
No full textI PCB inducono l'attivazione del protoncogene C-fos nelle cellule miogeniche L6.
No full textSUPPLEMENTO NOVEMBRE-DICEMBR
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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