102,064 research outputs found

    Letter to the Editor Evidence of Serological Cross-Reactivity between Genotype 1 and Genotype 3 Erythrovirus Infections

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    Candotti and colleagues (1) reported the prevalence of a third strain of human erythrovirus, genotype 3 (V9), in the Ghanaian population and, in part, concluded that a genotype 1 (B19)-based assay failed to detect genotype 3 immunoglobulin G (IgG) in 38.5% of Ghanaian samples containing genotype 3 antibodies. We disagree with this conclusion for the following reasons

    Preface

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    Evaluation of stress due to mixing in piglets

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    The aim of the present work was to evaluate the effect of mixing on some physiological indicators of welfare in piglets fed or not with a natural antioxidant supplementation. Fifty six piglets of average live weigh of 6 kg were allotted to two dietary treatments: control diet (CON, N=28) and diet supplemented with dietary plant antioxidant (1 kg/t feed) titrated at 0.5% of phenylpropanoids, expressed as verbascoside (PPG, N=28). After 30 days of dietary treatments, blood samples from 14 piglets/treatment were analysed for serum haptoglobin (Hp), cortisol, blastization of lymphocytes (BLA), aspartate amino transferase and birilubin (BIL) concentrations and blood antiradicalic activity through kit Radicaux libres (KRL) test, “SPIRAL Patent”, Couternon, France. After sampling, inside of the same dietary treatment, the half of animals were mixed with animals coming from another pen. After 2 days corresponding to the period able to develop a dominance hierarchy, blood samples of the new groups of animals were withdrawn for the same blood tests. Data were analysed by a GLM with dietary treatment and mixing as main effects. PPG diet tendentially (P=0.073) increased BLA and reduced (P<0.05) Hp; mixing reduced (P<0.05) BIL and increased BLA (P=0.003). PPG diet (P<0.05) and mixing (P<0.001) increased total antiradicalic activity in blood, expressed as the time (min) required to reach 50% of maximal hemolysis, referred to the whole blood resistance to free-radical attack. The present trial confirms the efficacy of dietary natural antioxidant evidenced by lower haptoglobin values in the PPG group than control; moreover KRL test has been able to discriminate pig welfare in relation to the stressful event such as mixing whereas the physiological parameters frequently used as indicators failed

    Prognostic Significance of Neutrophil/Lymphocytes Ratio (NLR) in Predicting Recurrence of Cervical Dysplasia

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    Objective: The objective of the present study was to investigate the potential prognostic role of neutrophil-lymphocyte ratio (NLR) in comparison with known parameters of prediction for the detection of recurrences of cervical intraepithelial neoplasia (CIN) after treatment. Methods: We retrospectively evaluated patients who underwent surgical treatment for CIN2, CIN3, and carcinoma in situ (CIN2+) between 2010 and 2019. NLR was recorded before surgery, and the follow-up records of patients were analyzed. Cases were splitted into two subgroups according to baseline NLR-low-NLR for <2 and high-NLR for ≥2 values of the index-and correlated with recurrences. Results: 428 cases fulfilled the criteria and were included in the study. Recurrence rate in patients with NLR <2.0 and NLR ≥2.0 was 15.2% and 27.3%, respectively, being the odd ratio for recurrence significantly higher in patients with NLR ≥2 (OR = 2.09; 95% CI 1.28-3.41; p = 0.003). A highly significant statistical difference in recurrence rate was demonstrated, in both univariate and multivariate, for surgical margins, follow-up HPV-DNA status, and NLR values. Conclusion: Preoperative NLR categorization is a strong independent prognostic factor for recurrences after surgical excision of CIN. NLR evaluation is a simple, reproducible, and cost-effective clinical instrument that could optimally be introduced in clinical practice in every setting

    Bibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung

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    Dieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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