1,720,967 research outputs found
Fratture pelviche nel cane e nel gatto: classificazione ed esami di 591 casi
Full text linkIn questo lavoro è presentato un sistema di classificazione delle fratture pelviche nei
piccoli animali, con esame e discussione di 591 casi raccolti presso il Dipartimento di Clinica
Veterinaria dell’Università di Pisa dall’anno 1996 all’anno 2006
.
Il sistema adottato si basa
su una modificazione del sistema di classificazione AO/ASIF, utilizzato in medicina umana
e in medicina veterinaria dei piccoli animali per la classificazione delle fratture delle ossa
lunghe, e già utilizzato e modificato in studi precedenti. Anche nel nostro caso è stato utilizzato
un sistema di classificazione basato su codici composti da numeri e lettere che indicano il
sito anatomico, la localizzazione, l’implicazione o meno degli elementi di carico e la gravità
della frattura pelvica. I casi sono stati valutati in base ad esami radiologici eseguiti nelle due
proiezioni standard, LL e VD, prendendo in considerazione solo i radiogrammi di buona e
ottima qualità. Lo scopo di questo studio è stato quello di elaborare un metodo di classificazione
che ci ha permesso di poter osservare 221 tipi di fratture pelviche diverse, in parte prese in
considerazione singolarmente ed in parte associate fra di loro, applicando 113 combinazioni
diverse di siti di frattura. Le fratture pelviche riscontrate più frequentemente sono risultate
essere quelle a livello del corpo dell’ileo con 157 casi su 591 (26,56%), considerando sia le
fratture del corpo dell’ileo semplici che quelle associate a fratture in siti diversi o a lussazione
sacro-iliaca, seguite da quelle acetabolari con 135 casi su 591 (22,84%). La combinazione
di fratture che è stata osservata più comunemente è quella della frattura del corpo dell’ileo
accompagnata dalla frattura della tavola dell’ischio e dell’osso del pube con 40 casi su 69
(57,97%), che presentavano fratture pelviche in siti diversi combinate fra lor
Reduced PTEN Protein Expression and Its Prognostic Implications in Canine and Feline Mammary Tumors
No full textPhosphatase and tensin homolog (PTEN) belongs to the group of gatekeeper tumor suppressor genes and is involved in multiple mechanisms leading to cellular defense against neoplastic transformation and progression. Twenty-four dogs and 17 cats were submitted to a 2-year follow-up study, and clinicopathologic features were recorded and compared with immunohistochemical PTEN staining. PTEN-negative status occurred in 33% of canine and 76% of feline mammary carcinomas. In canine mammary carcinomas, there was a significant (P < .05) correlation between loss of PTEN protein expression and simple carcinoma histotype, lymphatic vessel invasion, lymph node metastases, distant organ metastases, tumor dedifferentiation, tumor recurrence, and shorter overall survival. In feline mammary tumors, a significant correlation between loss of PTEN protein expression and lymphatic vessel invasion was found. Loss of PTEN expression could be a useful prognostic marker in canine mammary carcinomas
Valutazione radiografica delle variazioni della vascolarizzazione polmonare del gatto in due protocolli anestesiologici
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Comparison of sonographic and CT findings for the identification of renal nodules in dogs and cats
Full text linkUltrasonography (US) and computed tomography (CT) are used to diagnose neoplastic and non-neoplastic focal renal lesions in dogs and cats; however, comparative studies between these two diagnostic tools are lacking. The aim of this retrospective, methods comparison study was to evaluate and compare the performance of US compared to CT in identifying at least one renal nodule in animals with confirmed focal renal lesions. Imaging studies of animals with uni- or bilateral renal nodules smaller than 3 cm that underwent both US and CT and that had a pathologically confirmed diagnosis were reviewed. Animals with renal cysts and infarcts were excluded. Recorded features for both modalities included the following: shape, size, number, localization, margins, renal profile. For CT only, recorded features also included attenuation (HU) and pattern of enhancement. For US only, recorded features also included echogenicity, echostructure, and rate of visibility. Final diagnosis was obtained by cytology or histopathology. Using CT, lesions were identified in all 39 (100%) kidneys of 18 dogs and seven cats. Most lesions were multiple, cortical, well-defined, iso-attenuating (precontrast), hypo-attenuating, and moderately enhancing (postcontrast). Using US, lesions were identified in 29 of 39 (74%) kidneys. Overall, nine (31%) lesions were poorly visible; 10 (26%) kidneys appeared normal; in 17 (59%) organs, lesions’ number was underestimated. Isoechoic, non-protruding lesions were difficult to identify by US. Ultrasonography underestimated renal lesions compared to CT in 59% of the kidneys (P = 0.001). Final diagnoses included metastatic disease (n = 16), infiltration by feline lymphoma (n = 4), primary neoplasia (n = 3), and non-neoplastic benign lesions (n = 2)
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