3,483 research outputs found
Shakespeare and Space
No full textCo-editor of book, with Cong Cong, and author of the chapter 'London, Stratford, Coventry: Shakespearean theatre and the spaces of history
sj-pdf-1-ctj-10.1177_17407745211052486 – Supplemental material for Optimal one-stage design and analysis for efficacy expansion in Phase I oncology trials
No full textSupplemental material, sj-pdf-1-ctj-10.1177_17407745211052486 for Optimal one-stage design and analysis for efficacy expansion in Phase I oncology trials by Cai Wu, Fang Liu, Heng Zhou, Xiaoqiang Wu and Cong Chen in Clinical Trials</p
sj-docx-1-ctj-10.1177_17407745211052486 – Supplemental material for Optimal one-stage design and analysis for efficacy expansion in Phase I oncology trials
No full textSupplemental material, sj-docx-1-ctj-10.1177_17407745211052486 for Optimal one-stage design and analysis for efficacy expansion in Phase I oncology trials by Cai Wu, Fang Liu, Heng Zhou, Xiaoqiang Wu and Cong Chen in Clinical Trials</p
Impatiens bullatisepala (Balsaminaceae), a new species from Guizhou, China
No full textPeng, Shuai, Cong, Yi-Yan, Tian, Jing, Zhang, Cai-Fei, Hu, Guang-Wan, Wang, Qing- Feng (2021): Impatiens bullatisepala (Balsaminaceae), a new species from Guizhou, China. Phytotaxa 500 (3): 217-224, DOI: 10.11646/phytotaxa.500.3.5, URL: http://dx.doi.org/10.11646/phytotaxa.500.3.
Towards More Efficient Local Search for Pseudo-Boolean Optimization
No full textPseudo-Boolean (PB) constraints are highly expressive, and many combinatorial optimization problems can be modeled using pseudo-Boolean optimization (PBO). It is recognized that stochastic local search (SLS) is a powerful paradigm for solving combinatorial optimization problems, but the development of SLS for solving PBO is still in its infancy. In this paper, we develop an effective SLS algorithm for solving PBO, dubbed NuPBO, which introduces a novel scoring function for PB constraints and a new weighting scheme. We conduct experiments on a broad range of six public benchmarks, including three real-world benchmarks, a benchmark from PB competition, an integer linear programming optimization benchmark, and a crafted combinatorial benchmark, to compare NuPBO against five state-of-the-art competitors, including a recently-proposed SLS PBO solver LS-PBO, two complete PB solvers PBO-IHS and RoundingSat, and two mixed integer programming (MIP) solvers Gurobi and SCIP. NuPBO has been exhibited to perform best on these three real-world benchmarks. On the other three benchmarks, NuPBO shows competitive performance compared to state-of-the-art competitors, and it significantly outperforms LS-PBO, indicating that NuPBO greatly advances the state of the art in SLS for solving PBO
Propagation and damping of Alfvén waves in low solar atmosphere
No full textPropagation and damping of Alfvén waves in the inner solar corona are studied using a 2D magnetohydrodynamics (MHD) simulation code with realistic density and temperature profiles in a uniform background magnetic field. A linear wave is launched by ascribing a sinusoidal fluid motion at about 1000 km from the surface of the Sun, which is shown to generate Alfvénic wave motions along the height. The 2D MHD simulation shows that for B0 ≈ 3G, Alfvén waves of about 10-2 Hz with an infinite horizontal length-scale can penetrate into the corona, transferring about 90 per cent their energies. This raises the possibility that the wave can be dissipated by various physical processes. The results show that the propagating wave can effectively damp via viscosity in the lower region of the corona, if a horizontal scale of granular size is incorporated. © 2017 The Author
Kinetics and mechanisms of bacteriophage PR772 inactivation by monochloramine
No full textWith billions of people living with unsafe drinking water sources, ensuring safe drinking water remains a challenging task for environmental engineers and researchers. Human Adenovirus (HAdV) is a pathogen listed in the Contaminant Candidate List 4 of the United States Environmental Protection Agency. HAdV is highly resistant to monochloramine, a common drinking water disinfectant used in the United States and other countries around the world. PR772 is believed to relate evolutionarily to HAdV, which makes PR772 a potential surrogate virus for HAdV. Previous research characterized the monochloramine inactivation kinetics of both viruses, and found that the inactivation kinetics at high pH and high temperature was characterized by a phase of slower rate followed by faster rate, which was different from the more common fast-slow or tailing kinetics observed for other pH-temperature combinations, for both viruses as well as for other microorganisms. This thesis further characterized the kinetics of PR772 inactivation by monochloramine at high pH and high temperature, and proposed a two-reaction model to describe the data. Molecular analyses at various stages of the replication cycle were used to determine which viral replication step was hindered by monochloramine disinfection at pH 8.0-30.0℃ (baseline condition) and pH 10.5-30.0℃ (high pH and high temperature condition). The results showed that early mRNA synthesis, DNA production and late mRNA synthesis were all inhibited. Different from previous research on lower temperature and pH, partial genome damage and loss in viral attachment were observed. No difference between the two pH levels investigated was observed.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2020-05-01The student, Wen Cong, accepted the attached license on 2018-04-10 at 11:38.The student, Wen Cong, submitted this Thesis for approval on 2018-04-10 at 11:55.This Thesis was approved for publication on 2018-04-10 at 15:12.DSpace SAF Submission Ingestion Package generated from Vireo submission #12162 on 2018-08-31 at 17:26:16Made available in DSpace on 2018-09-04T20:46:58Z (GMT). No. of bitstreams: 2
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Previous issue date: 2018-04-10Embargo set by: Seth Robbins for item 107374
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Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 107374
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Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction set for Item 107374 on 2020-06-15T19:14:49Z with date 2020-09-04 by [email protected] Restriction Lifted for Item 107374 on 2020-09-04T09:15:18Z
SPDAs and GICs: like money in the bank?
No full textWe argue that changes in the life insurance industry have created a nontrivial moral hazard. We document the industry's shift from sales of life insurance to sales of mainly rate-of-return oriented investments like single premium deferred annuities (SPDAs) and guaranteed investment contracts (GICs). We describe the system of explicit and implicit guarantees that state governments and the industry provide to SPDA and GIC investors. We argue that these guarantees create moral hazards that have contributed to insurance company failures and misallocation of resources. We summarize reformers' proposals to enhance both the explicit guarantees and the regulation of insurance companies and argue that maintaining the degree of regulatory tightness required for such proposals to succeed will be difficult. We suggest an alternative: eliminate guarantees of SPDAs, GICs, and similar products (and possibly promote full disclosure practices and earmarked investments like variable annuities).Insurance industry
Impatiens bullatisepala G. W. Hu, Y. Y. Cong & Q. F. Wang 2021, sp. nov.
No full text<i>Impatiens bullatisepala</i> G.W. Hu, Y.Y. Cong & Q.F. Wang <i>sp. nov.</i> (Figures 1, 2: A–D) <p> <b>Diagnosis:</b> —The new species is morphologically similar to <i>Impatiens davidii</i>, but can be distinguished with the latter by its lateral sepals suborbicular, 1–1.5 cm in diameter, midrib ridged dorsally, lateral veins reticulate and sunk on the abaxial surface with bullate projections among veins; dorsal petal broadly ovate, 1–1.5 × 1.5–2 cm, dorsally with a green narrow arcuate cristate crest.</p> <p> <b>Type</b>:— CHINA. Guizhou province, Jiangkou County, Fanjing Mountain, under evergreen broad-leaved forest, 27°53′44.21″N, 108°43′16.4″E, elevation 1027 m, 15 September 2018, <i>Shuai Peng PS-0052</i> (holotype: HIB!; Isotype: HIB!, HNNU!)</p> <p>Herbs annual, to 100 cm tall. Stem erect or procumbent in lower part, succulent, branched, glabrous, lower nodes swollen with many fibrous roots. Leaves alternate, petiolate; petiole 0.5–2 cm long; lamina elliptic to elliptic-lanceolate, 6–10 × 3–4.5 cm, margin coarsely crenate, teeth mucronulate, base obtuse to cuneate, with 3–4 pairs of glands, apex caudate-acuminate; glabrous; lateral veins 5–7 pairs. Inflorescences in upper leaf axils, 1-flowered; peduncle 1.8–2.8 cm long. Pedicel with 2 bracts above middle; bracts alternate, glabrous, upper one ovate, ca. 6 × ca. 4 mm, lower one subulate, ca. 2–3 mm long. Flower yellow, 4–5.5 cm long. Lateral sepals 2, sub-orbicular, 1–1.5 cm in diameter, apex mucronulate, margin entire, yellowish-green, glabrous, midrib ridged dorsally, lateral veins reticulate and sunk on abaxial surface with bullate projections among veins,; lower sepal deeply saccate, 2–2.5 cm deep, yellow with 6–7 orange red striations, glabrous; apex gradually narrowed into an abruptly incurved spur, spur 2-lobed, 1–1.3 cm long; mouth 1.5–1.9 cm wide, oblique with ca. 0.8 cm long narrowly triangular tip. Dorsal petal broadly ovate, 1–1.5 × 1.5–2 cm, apex emarginate and mucronulate, dorsally with a green narrow arcuate cristate crest at midvein; lateral united petals 2-lobed, 2.4–3.2 cm long, basal lobe ovate to elliptic, 5–7 × 3–5 mm, small, upper part with purple-red patches, apex abruptly narrowed into a purple-red filiform appendage, appendage up to 1 cm long; distal lobe dolabriform, 1.8–2.3 × 0.9–1.4 cm, yellow with red spots at base, inner margin curled with small auricle, apex with a short yellow filiform appendage. Stamens up to 4 mm long, filaments linear, slightly swollen above; anthers ovoid-orbicular, apex obtuse. Ovary erect, fusiform. Capsule linear, 2.8–3.5 cm long. Seed unknown.</p> <p> <b>Distribution and ecology:</b> — <i>Impatiens bullatisepala</i> is currently known only from the type locality in Fanjing Mountain, Guizhou Province, China. It grows under the moist evergreen broad-leaved forests along the side of a creek.</p> <p> <b>Etymology:</b> —The specific epithet “ <i>bullatisepala</i> ” refers to the lateral sepals with bullate projections netted in sunk reticulate veins on abaxial surface. The Chinese name is “泡ḛâ仙"”.</p> <p> <b>Phenology:</b> —The new species was observed flowering from September to October, fruiting from October to November.</p> <p> <b>Phylogenetic position:</b> —Bayesian phylogenetic analyses of the combined ITS and <i>atpB-rbcL</i> datasets proved its position within the <i>Impatiens</i> sect. <i>Impatiens</i> and closely related to <i>I. davidii</i> in the phylogenetic tree (Figure 3).</p> <p> <b> <i>V</i> oucher specimens of <i>Impatiens davidii</i>:</b> — China. Hunan: Yongshun County, Xiaoxi National Natural Reserve, 28°48′N, 110°11′E, elevation 650 m, 15 August 2018, <i>S. Peng PS-0051</i> (HIB); Jiangxi: Jiujiang City, Lushan Mountain, Guling Township, 29°34′N, 115°58′E, elevation 1050 m, 11 October 2018, <i>G.W. Hu & S. Peng HGW-001138</i>, <i>G.W. Hu & S. Peng HGW-001140</i>, <i>G.W. Hu & S. Peng HGW-001142</i> (HIB).</p>Published as part of <i>Peng, Shuai, Cong, Yi-Yan, Tian, Jing, Zhang, Cai-Fei, Hu, Guang-Wan & Wang, Qing- Feng, 2021, Impatiens bullatisepala (Balsaminaceae), a new species from Guizhou, China, pp. 217-224 in Phytotaxa 500 (3)</i> on pages 220-221, DOI: 10.11646/phytotaxa.500.3.5, <a href="http://zenodo.org/record/5424624">http://zenodo.org/record/5424624</a>
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