4,803 research outputs found
Colorimetric and HPLC-DAD and bioactivity of Goji phytocomplex components
No full textLycium barbarum L, commonly known as Goji, is originally cultivated in China and Tibet and represents a medicinal plant in the Traditional Chinese Medicine. Several Goji cultivars from Italy and Romania, coming from different harvesting dates and seasons, were submitted, after a simple homogenization, to colorimetric CieLab analysis. The obtained organic and hydroalcoholic extracts were characterized in their quali-quantitative profile of carotenoid or polyphenolic components by HPLC-DAD analysis. Total phenolic content, total flavonoid content, antioxidant and scavenger anti-Candida and anti-tyrosinase activity were evaluated.
Samples belonging to “Polonia” and “Wild” varieties harvested in three different dates in 2015 and in two different dates in 2016 at Fondi, (Lazio, Italy) samples belonging to “Sweet” and “Big” varieties harvested in two different dates in 2017 at Subiaco (Lazio, Italy) and to “Erma” and “Biglifeberry” varieties coming from Romania were evaluated.
HPLC-DAD analyses, TPC, TFC, antioxidant, scavenging, anti-Candida and anti-tyrosinase activity were performed according to previously described methods. (1,2,3)
CIELAB parameters (L*, a*, b*, C*ab and hab) were recorded on a Colorimeter X-Rite SP-62 (D65 illuminant, observer angle of 10°) equipped with an integration sphere to determine the color reflectance. (4)
A double phase extraction from the homogenized fruits allows to simultaneously separate an organic and hydroalcoholic phase, containing the carotenoid and the phenolic components submitted to HPLC-DAD analysis. Zeaxanthin dipalmitate, rutin and carvacrol were the most represented molecules and were quantified by calibration curves.
HPLC-DAD analyses confirm that Goji berries represent an exceptional source of zeaxanthin, and a good source of rutin and carvacrol.
Both TPC and TFC showed a good correlation with the HPLC data and the antioxidant and scavenging activity. A correlation was attempted among carvacrol content and anti-Candida activity.
Colorimetric analyses show that different homogenization techniques influence the distribution of pigments in the matrix, so that the purees resulting color is different also if pigment content should be the same. A good correlation was found among color expressed by simple homogenized samples and carotenoid content of the related extracts, showing that colorimetric measurement can represent a crucial point in the design of a processing flow chart for juices preparation.
Preliminary encouraging results about the tested activities on polyphenolic fraction need to be carefully evaluated in order to assess the Goji berry potential use in food suppliers.
1) Boutaoui, Zaiter, Benayache, Benayache, Carradori, Cesa, ... & Locatelli, M. (2018), Molecules, 23(2), 463.
2) Mocan, Moldovan, Zengin, Bender, Locatelli, Simirgiotis, ... & Crișan, G. (2018). Food and Chemical Toxicology,115, 414-424
3) Simonetti, D’Auria, Mulinacci, Milella, Antonacci, Innocenti, & Pasqua, (2017). Phenolic content and in vitro antifungal activity of unripe grape extracts from agro-industrial wastes. Natural Product Research, 1-5.
4) Patsilinakos, Ragno, Carradori, Petralito, Cesa, (2018). Food Chemistry
Francesco Scorza Barcellona o della passione agiografica
No full textL'autrice traccia, sul filo dei ricordi, il profilo scientifico ed umano di Francesco Scorza Barcellona ed introduce gli studi raccolti nel volume.The author traces, on the thread of memories, the scientific and human profile of Francesco Scorza Barcelona and introduces the studies collected in the book
Delle lodi di don Francesco Medici de' principi di Toscana : orazione /
No full textEngraved t.p. vignette of Medici arms. On recto of 2nd leaf is Callot's full-page engraved port. of Francesco de' Medici, son of Grand Duke Ferdinand I. It is in Lieure's 1st state. The port. also appeared the same year in Alessandro Adimari's Esequie dell' ill.mo & ecc.mo principe don Francesco Medici (Florence : Gio. Donato & Bernardino Giunti); see Lieure. Large woodcut Giunti device on p. [31].Lieure, J. Jacques Callot,Mode of access: Internet.At head of front pastedown is bookplate of Francesco Riccardi de Vernaccia (Florence, ca. 1780; see Gelli, p. 387). Below it is the label of Horatius (Orazio) Landau, with stamped shelfmark 53021. At foot is the bookplate of U. Manganelli, signed with the initials SER. A dedicatory inscription at foot of t.p. has been scratched out.Binding: modern marbled paper, backed in green vellum. Date, author & title writte on spine.Port. trimmed into the image at right margin and foot
Frankenstein
No full text@inproceedings{orsini2015graph,
title={Graph invariant kernels},
author={Orsini, Francesco and Frasconi, Paolo and De Raedt, Luc},
booktitle={IJCAI Proceedings-International Joint Conference on Artificial Intelligence. IJCAI},
year={2015}
A review on the dietary flavonoid Tiliroside
No full textAmong flavonoid derivatives, tiliroside is a flavonoid contained in several edible plants or specific plant parts (fruits, leaves, or roots). These parts are often widely used as both food and medicines, in the treatment of various ailments and, in some cases, as food supplements. Considering the easy access to many publications concerning tiliroside and the lack of a review that summarizes the current progress in studies on its safety, efficacy, and presence in the plant kingdom, we present here a review paper on tiliroside and its principal derivatives. The paper also highlights the basic knowledge regarding this molecule, its derivatives, and the analytical approaches used for extraction and quantification, as well as reports on the biological activities against different key enzymes linked to various human diseases. The reported information is also devoted to highlighting the concept “learn from nature to discover new products”, particularly in the development of new drugs, food supplements, and nutraceuticals, starting from a natural lead compound such as tiliroside and improving its biological activities (and selectivities) against a specific target for therapeutic purposes
Polyphenols from Lycium barbarum (Goji) Fruit European Cultivars at Different Maturation Steps: Extraction, HPLC-DAD Analyses, and Biological Evaluation
No full textGoji berries are undoubtedly a source of potentially bioactive compounds but their phytochemical profile can vary depending on their geographical origin, cultivar, and/or industrial processing. A rapid and cheap extraction of the polyphenolic fraction from Lycium barbarum cultivars, applied after homogenization treatments, was combined with high-performance liquid chromatography (HPLC) analyses based on two different methods. The obtained hydroalcoholic extracts, containing interesting secondary metabolites (gallic acid, chlorogenic acid, catechin, sinapinic acid, rutin, and carvacrol), were also submitted to a wide biological screening. The total phenolic and flavonoid contents, the antioxidant capacity using three antioxidant assays, tyrosinase inhibition, and anti-Candida activity were evaluated in order to correlate the impact of the homogenization treatment, geographical origin, and cultivar type on the polyphenolic and flavonoid amount, and consequently the bioactivity. The rutin amount, considered as a quality marker for goji berries according to European Pharmacopeia, varied from ≈200 to ≈400 µg/g among the tested samples, showing important differences observed in relation to the influence of the evaluated parameters
Didattica e ricerca. L’esperienza del Laboratorio aragonese e sforzesco
No full textIn the workshop on Diplomatic correspondences in the Italian Renaissance, directed in January-May 2018 by Francesco Storti and Francesco Senatore in the Istituto italiano per gli studi filosofici of Naples, 12 undergraduate and graduate students learned to read and trascribe italian diplomatic dispatches of the 15th cent., producing a specimen of scientific edition. In the opinion of the author, such activities and similar ones are very useful for future school teachers and scholars and they could be introduced in the university and pHD courses of history. Students of humanistic sciences should have concrete contacts with the historical research on primary sources. On the other hand, editing of historical sources could become a marginal activity because it is not enough appreciated in the current research evaluation processes.
Keywords: Didattica, edizione documentaria, diplomazia rinascimentale; education, documentary edition, renaissance diplomac
LA MADONNA ESTERHAZY DI RAFFAELLO
No full textLA MADONNA ESTERHÁZY DI RAFFAELLO A PALAZZO MARINO, di Francesco Murano,
Fotografie di Sergio Oriani
Il curatore della mostra, Stefano Zuffi, ha voluto inquadrare criticamente l’opera di Raffaello
proveniente dal Museo di Budapest, ponendola tra la Vergine delle Rocce di Francesco Melzi,
proveniente dall’Istituto delle Suore Orsoline di Milano e la Madonna della Rosa di Giovanni
Antonio Boltraffio, proveniente dal Museo Poldi Pezzoli della stessa città. L’architetto Corrado
Anselmi ha progettato un affascinante allestimento, concependolo come un percorso che si
sviluppa attraverso tre soste utili all’ammirazione delle opere. L’autore Francesco Murano,
spiega con ricchezza di particolari i vincoli del progetto illuminotecnico e le scelte luministiche.Once again, for the Christmas season, the Municipally of Milan decided to display an important work in the frame of the Palazzo Marino’s Alessi Hall. For this year 2014, the choice has been to propose the Estheràzy Madonna by Raphael, from the Museum of Budapest.
The exhibition curator, Stefano Zuffi, wanted to critically frame to work of Raphael by placing it between the Vegine delle Rocce (Virgin of the Rocks) by Francesco Melzi, coming from the Milan’s Istituto delle Suore Orsoline, and the Madonna della Rosa by Giovanni Boltraffio, from the Milanese Museo Poldi Pezzoli.
The Architect Corrado Anselmi designed a fascinating display, convinced as a path that develops through three stops that are useful for the enjoyment of the works.
The author Francesco Murano, explains with many details the lighting design project
Phantasy, Multiverse and Protopia: Ran Slavin's Israeli Futurism
No full textThe essay discusses Israeli artist Ran Slavin's transmedia production, since the 1990s, as a key example of Israeli Futurism. The essay contextualizes Slavin's films, multimedia installations, photography, soundscapes, CGI imagery, and tech-based output as a way to process the conflictual dynamics at the basis of the foundation of Israel, the mythologies of Judaism and the ongoing metamorphosis of Jewish identity. The author of this essay, Francesco Spampinato, is also the editor of this major retrospective monograph on Slavin's work
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