1,720,960 research outputs found
Simultaneous occlusion of three cilioretinal arteries following scleral buckling surgery under local anesthesia
Full text linkBACKGROUND:
Cilioretinal artery (CRA) occlusions are rare in young patients. In these cases, the most commonly associated causes are considered to be the same as those implicated in central retina artery occlusions, such as vasculitic processes, migraine, cardiac disorder, and coagulation abnormality. The aim of this article was to report for the first time the medical records and investigational results of an unusual case of simultaneous occlusion of three CRAs after scleral buckling surgery under local anesthesia.
METHODS:
A complete ophthalmic examination, including color fundus image, fundus fluorescein angiography, optical coherence tomography, visual field, as well as systemic and laboratory assessments, was performed.
RESULTS:
A case of contemporaneous blockage of three CRAs after ab externo surgery for retinal detachment in a 29-year-old Caucasian woman was reported. The interdisciplinary approach and the imaging results have allowed us the clinical definition of such a very rare case.
CONCLUSION:
Here, we reported that optical coherence tomography is an indispensable tool to better delineate the pathological process and follow atrophic changes in the macula, especially in cases in which fundus fluorescein angiography and systemic tests may be poorly informativ
Shifting and sliding of medial-inferior conjunctival flap for surgical treatment of Pterygium
No full textPurpose:To describe a novel surgery technique in the treatment of primary pterygium and to evaluate its safety and rate of recurrence.
Methods:Retrospective case series. Between January 2012 and October 2013, escluded summer months, 128 patients, of which 103 were men and 25 women, all living in Sardinia (Italy) were operated on for a primary nasal pterygium. The mean age was 55,61 ± 9,93 (range 33-75). Pterygium excision was combined with a sliding and shifting congiuntival flap technique. The flap harvested from the medial inferior bulbar conjunctiva was placed over the bare sclera and glued with Tisseel (Baxter AG, Vienna), a human tissue glue. Topical and oral steroids and antibiotic eyedrops were prescribed, and the eye was patched for 1 day.
Results:Patients were followed up for at least 1 year, and the outcomes and recurrence rates were evaluated. In case of fibrovascular regrowth, it was manifested by third month of follow up, but progression arrested before sixth month control. Six patients showed a corneal invasion between 1 and 2.5 mm beyond the limbus, in 1 patient the new fibrovascular tissue was 4.5 mm . The recurrence rate estimated at 1 year after surgery was 5.46%. No intraoperative complication was observed. The mean surgery time was 10.30’’ ± 1.30” minutes.
Conclusions:The sliding and shifting congiuntival flap technique is a safe alternative in pterygium surgery for preventing recurrence. It is technically easier than congiuntival autograft and reduces operative time. Moreover the low rate of recurrence could be positively influenced by the reduced inflammatory reaction due to the absence of a congiuntival suture
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Humphrey visual field 10-2 and macular retinal thickness correlations in glaucomatous patients.
No full textPurpose:To provide a quantitative comparison between the macular retina thickness (MRT) and the Humphrey visual field (HVF) 10-2 SITA-standard strategy parameters in glaucomatous patients.
Methods:Retrospective statistical analysis of spectral domain optical coherence tomography macular cube scans 512x128 (Cirrus HD-OCT 4000, Carl Zeiss Meditec, Inc. , Dublin, CA) compared with HVF mean deviation (MD) and pattern standard deviation (PSD) in sixty eyes of thirty-six glaucomatous subjects. Abnormal MRT on OCT was defined as an average macular thickness value of any one of four quadrants to be less than 5% of normative database.
Results:Eighteen (30% ) glaucomatous eyes showed an abnormal MRT. In patients with reduced MRT the mean was 236,8 μm, whereas in patients with normal MRT the mean was 264,3 μm. In eleven eyes with MRT reduction the average MD was -10,56 dB, and PSD was greater than 2,5 dB in seven of these eleven eyes. In 61% of glaucomatous patients there was a correlation between MRT and MD.
Conclusions:In glaucomatous patients, OCT macular retinal thickness analysis may help in detecting the existence of a visual field defec
Rebound macular edema following oral acetazolamide therapy for juvenile X-linked retinoschisis in an Italian family
Full text linkVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Efficacy of oral acetazolamide and topical dorzolamide therapy for X-linked juvenile retinoschisis maculopathy
No full textPurpose: To evaluate the response of macular cysts after treatment with acetazolamide tablet or dorzolamide eye drops in 2 brothers with juvenile X-linked retinoschisis (XLRS).
Methods: We carried out a retrospective evaluation of two brothers (four eyes) with XLRS, treated with acetazolamide tablet (375 mg daily) for three months, followed by dorzolamide 2% eye drops three times a day for further three months. The change in best-corrected visual acuity (VA) and central macular thickness (CMT; central 1 mm subfield thickness) from optical coherence tomography (OCT) was analysed over the follow-up period. Genetic analysis for mutations in the retinoschisis gene (RS1) was also performed.
Results: The age of patients at the start of treatment was 18 and 20 years, and follow-up duration was 6 months. In patient 1 CMT at the final follow-up was significantly better than at baseline (RE 563 vs 430 μm, LE 501 vs 277 μm), as well as VA (RE 3/10 (0,522 logMAR) LE 3/10 (0,522 logMAR).vs RE 6/10 (0,221 logMAR), LE 5/10 (0,301 logMAR) ); in patient 2 CMT at the final follow-up was also better than at baseline (RE 496 vs 416 μm, LE 519 vs 455 μm), hoever VA remained unchanged (RE 4/10 (0,397 logMAR) and LE 5/10 (0,301 logMAR)). Oral acetazolamide administered for three months achieved a substantial reduction of macular cysts and, to a lesser extent, of visual acuity, with no adverse effects. The topical 2% dorzolamide did not obtain a further reduction of CMT and the visual acuity was unchanged. Sequence analysis of the RS1 gene identified a hemizygous 589C>T (Arg197Cys) missense mutation in exon 6. The patients' mother was heterozygous 589C/T and also an unaffected sister was heterozygous for this mutation. This mutation has not been previously reported in Italian families with XLRS.
Conclusions: This study showed that both oral acetazolamide and topical dorzolamide have effect in reducing or stabilize central macular thickness and improve or stabilize VA in 2 patients with XLRS maculopathy associated with a hemizygous 589C>T (Arg197Cys) missense mutation in exon 6. Given the potential requirement for long term treatment, the utility of acetazolamide may be limited by potential systemic side effects, while a topical medication would be preferable for long term treatment
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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