111 research outputs found
Valutazione della circolazione intracranica mediante Doppler Transcranico (TCD) in pazienti affetti da diabete mellito di tipo 2.
No full textAge-related Changes of Periodic Leg Movements during Sleep in Patients with Restless Legs Syndrome
No full textIntracranial arterial flow assessed by transcranial Doppler (TCD) in patients with type 2 diabetes.
No full textThe Poetry Anthology Ar-Robi fii qalbi by Sofi Ghoniyah: A Sociology of Author Perspective
No full textThis study aims to determine the sociology of the author in the poetry anthology Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren. This research focuses on four aspects, namely (1) the social background of the author in the anthology of poetry Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (2) the author\u27s social integration in the poetry anthology Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (3) author\u27s economic sources in the poetry anthology Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (4) professionalism in the authorship of Sofi Ghoniyah\u27s anthology of poetry Ar-Robi fii Qalbi based on the perspective of Rene Wellek and Austin Warren. This type of research is qualitative research. The data source of this research uses an anthology of poetry entitled "Ar-robi fii qalbi" by Sofi Ghoniyah. While the secondary data sources of this research were obtained from reading books or journals discussing the sociological theory of the authors Rene Wellek and Austin Warren. Data collection techniques in this study used interview techniques and note-taking techniques. The data validation technique used in this study is to increase persistence, triangulate data, and discuss with colleagues and experts. Meanwhile, for the data analysis technique, this research uses the Miles and Huberman method, namely data reduction, data presentation, and drawing conclusions. The researchers produced several data, namely (1) the author of the poetry anthology Ar-Robi fii qalbi is an educated author and has close interactions with her environment. (2) The author of the poetry anthology Ar-Robi fii qalbi has a high degree of integration. He mingles with the general public. (3) The main economic source of the author in Ar-Robi\u27s poetry anthology is not through her work but in her educational activities. As a teacher, her work is often used as learning material for her students. (4) The author of the poetry anthology Ar-Robi fii qalbi has high professionalism in the authorship of her work
The poetry anthology Ar-Robi fii qalbi by Sofi Ghoniyah: a sociology of author perspective (sertifikat hak cipta)
No full textThis research focuses on four aspects, namely (1) the social background of the author in the anthology of poetry Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (2) the author's social integration in the poetry anthology Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (3) author's economic sources in the poetry anthology Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (4) professionalism in the authorship of Sofi Ghoniyah's anthology of poetry Ar-Robi fii Qalbi based on the perspective of Rene Wellek and Austin Warren.This type of research is qualitative research. The data source of this research uses an anthology of poetry entitled "Ar-robi fii qalbi" by Sofi Ghoniyah.While the secondary data sources of this research were obtained from reading books or journalsdiscussing the sociological theory of the authors Rene Wellek and Austin Warren. Data collection techniques in this study used interview techniques and note-taking techniques. The data validation technique used in this study is to increase persistence, triangulate data, and discuss with colleagues and experts. Meanwhile, for the data analysis technique, this research uses the Miles and Huberman method, namely data reduction,data presentation, and drawing conclusions.The researchers produced several data,namely (1) the author of the poetry anthology Ar-Robi fii qalbi is an educated author and has close interactions with herenvironment. (2) The author of the poetry anthology Ar-Robi fii qalbi has a high degree of integration. He mingles with the general public. (3) The main economic source of the author in Ar-Robi's poetry anthology is not through herwork but in her educational activities. As a teacher, herwork is often used as learning material for her students. (4) The author of the poetry anthology Ar-Robi fii qalbi has high professionalism in the authorship of her work
The poetry anthology Ar-Robi fii qalbi by Sofi Ghoniyah: a sociology of author perspective (sertifikat hak cipta)
No full textThis research focuses on four aspects, namely (1) the social background of the author in the anthology of poetry Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (2) the author's social integration in the poetry anthology Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (3) author's economic sources in the poetry anthology Ar-Robi fii Qalbi by Sofi Ghoniyah based on the perspective of Rene Wellek and Austin Warren; (4) professionalism in the authorship of Sofi Ghoniyah's anthology of poetry Ar-Robi fii Qalbi based on the perspective of Rene Wellek and Austin Warren.This type of research is qualitative research. The data source of this research uses an anthology of poetry entitled "Ar-robi fii qalbi" by Sofi Ghoniyah.While the secondary data sources of this research were obtained from reading books or journalsdiscussing the sociological theory of the authors Rene Wellek and Austin Warren. Data collection techniques in this study used interview techniques and note-taking techniques. The data validation technique used in this study is to increase persistence, triangulate data, and discuss with colleagues and experts. Meanwhile, for the data analysis technique, this research uses the Miles and Huberman method, namely data reduction,data presentation, and drawing conclusions.The researchers produced several data,namely (1) the author of the poetry anthology Ar-Robi fii qalbi is an educated author and has close interactions with herenvironment. (2) The author of the poetry anthology Ar-Robi fii qalbi has a high degree of integration. He mingles with the general public. (3) The main economic source of the author in Ar-Robi's poetry anthology is not through herwork but in her educational activities. As a teacher, herwork is often used as learning material for her students. (4) The author of the poetry anthology Ar-Robi fii qalbi has high professionalism in the authorship of her work
Sequence analysis of leg movements during sleep with different intervals (<10, 10-90 and >90 s) in restless legs syndrome
No full textThe aim of this study was to define the time structure of leg movements during sleep occurring with an intermovement interval (onset-to-onset) shorter than 10 s in patients with restless legs syndrome and controls, and to compare it to the structure of movements with intervals of 10-90 s or >90 s. Polysomnographic recordings of 141 untreated patients and 68 age-matched normal controls were analysed. All movements were detected and classified into three categories, separated by intervals of 90 s. The number of movements included in each category was significantly higher in patients than in controls. The movements with an interval of >90 s occurred steadily during the night, whereas the hourly distribution of movements with intervals of 90 s. The time structure features of the three categories of movements considered in this study were found to be clearly different. This, together with previous observations on the differential effects of dopamine agonists on movements with different intervals, suggests that movements with intervals of 90 s are regulated by neurotransmitter mechanisms different from those modulating movements with an interval of 10-90 s
Narcolepsy type 1 features across the life span: age impact on clinical and polysomnographic phenotype
No full textStudy Objectives: Narcolepsy type 1 (NT1) is a chronic neurological disorder typically arising during adolescence and young adulthood. Recent studies demonstrated that NT1 presents with age-specific features, especially in children. With this study we aimed to describe and to compare the clinical pictures of NT1 in different age groups.Methods: In this cross-sectional, multicenter study, 106 untreated patients with NT1 enrolled at the time of diagnosis underwent clinical evaluation, a semistructured interview (including the Epworth Sleepiness Scale), nocturnal video-polysomnography, and the Multiple Sleep Latency Test. Patients were enrolled in order to establish 5 age-balanced groups (childhood, adolescence, adulthood, middle age, and senior).Results: The Epworth Sleepiness Scale score showed a significant increase with age, while self-reported diurnal total sleep time was lower in older and young adults, with the latter also complaining of automatic behaviors in more than 90% of patients. Children reported the cataplexy attacks to be more frequent (> lid in 95% of patients). "Recalling an emotional event," "meeting someone unexpectedly," "stress," and "anger" were more frequently reported in adult and older adult patients as possible triggers of cataplexy. Neurophysiological data showed a higher number of sleep-onset rapid eye movement periods on the Multiple Sleep Latency Test in adolescent compared to senior patients and an age-progressive decline in sleep efficiency.Conclusions: Daytime sleepiness, cataplexy features and triggers, and nocturnal sleep structure showed age-related difference in patients with NT1; this variability may contribute to diagnostic delay and misdiagnosis
Greedy Sensor Selection: Leveraging Submodularity Based on Volume Ratio of Information Ellipsoid
No full textThis article focuses on greedy approaches to select the most informative k sensors from N candidates to maximize the Fisher information, i.e., the determinant of the Fisher information matrix (FIM), which indicates the volume of the information ellipsoid (VIE) constructed by the FIM. However, it is a critical issue for conventional greedy approaches to quantify the Fisher information properly when the FIM of the selected subset is rank-deficient in the first (n-1) steps, where n is the problem dimension. In this work, we propose a new metric, i.e., the Fisher information intensity (FII), to quantify the Fisher information contained in the subset S with respect to that in the ground set N specifically in the subspace spanned by the vectors associated with S. Based on the FII, we propose to optimize the ratio between VIEs corresponding to S and N. This volume ratio is composed of a nonzero (i.e., the FII) and a zero part. Moreover, the volume ratio can be easily calculated based on a change of basis. A cost function is developed based on the volume ratio and proven monotone submodular. A greedy algorithm and its fast version are proposed accordingly to guarantee a near-optimal solution with a complexity of O Nkn-3 and O Nkn2, respectively. Numerical results demonstrate the superiority of the proposed algorithms under various measurement settings.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Signal Processing System
Complete sequencing of the FII plasmid pHK01, encoding CTX-M-14, and molecular analysis of its variants among Escherichia coli from Hong Kong
No full textObjectives: We characterized plasmids encoding CTX-M-14 β-lactamase originating from Escherichia coli isolates recovered from patients with uncomplicated cystitis or individuals with faecal colonization in Hong Kong from 2002 to 2004. Methods: Plasmids carrying CTX-M-14 were studied by conjugation, replicon typing, S1 nuclease-PFGE and plasmid PCR-restriction fragment length polymorphism (RFLP). The complete sequence of pHK01, a 70 kb plasmid encoding CTX-M-14 from an E. coli strain, was determined and the results compared with reference plasmids and aligned with GenBank data. Results: The bla CTX-M-14 plasmids could be transferred in 23 of 44 E. coli strains tested. Among the 23 transconjugants, the replicon types of the CTX-M-14-encoding plasmid were FII (n=13), I1-Iγ (n=4), F1B (n=2), FII and I1-Iγ (n=1), K (80 kb, n=1) and undetermined (n=2). Plasmid pHK01 (FII replicon) shares a high degree of homology with R100 except mainly for a 11 kb variable region containing bla CTX-M-14 (with an upstream ISEcp1 and a downstream truncated IS903), an iron transport system, an outer membrane protein (malB, maltoporin) and a putative toxin-antitoxin plasmid stability system (yacABC). It was highly related to bla CTX-M-14 (pKF3-70) and bla CTX-M-24 (pEG356) plasmids reported from mainland China in 2006 and Vietnam in 2007, respectively. Subtyping by a plasmid PCR-RFLP scheme showed that 10 of the 13 FII plasmids originating from isolates collected by multiple laboratories exhibited either identical or highly similar profiles. Conclusions: This study showed that narrow host-range FII plasmids play important roles in the dissemination of CTX-M-14. FII plasmids closely related to pHK01 have disseminated widely in the Hong Kong community. © The Author 2011. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved.link_to_OA_fulltex
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