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This is a letter in reply to Masuccio et al (J Pediatr 2009;155:454), who commented an article published by Cortese S, myself, et al. (J Pediatr 2009;154:86-90). In this letter we suggest that the cross sectional nature of our study could not allow to infer causality and psychopathological/pathophysiological pathways in the relationship between body size and depressive symptoms. Moreover, to prove that insulin resistance may lead to depressive symptoms in obese adolescents, as hypothesized by Masuccio et al., a longitudinal design and appropriate regression analyses, should be conducted
Neonatal Immunology
Cortese, Victor S.. (2004). Neonatal Immunology. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/109088
Théologie, droit canonique et droit romain. Aux origines du droit savant (XIe-XIIe s.)
Cortese Ennio. Théologie, droit canonique et droit romain. Aux origines du droit savant (XIe-XIIe s.). In: Comptes rendus des séances de l'Académie des Inscriptions et Belles-Lettres, 146ᵉ année, N. 1, 2002. pp. 57-74
La valutazione del surplus idrico nel sottobacino Iudeo–Bucari (bacino del fiume Mazaro-TP).
Review:ADHD impairs quality of life, but children and young people with ADHD perceive less impairment than parents
The Role of the Court of Justice of the European Union in Protecting Disability Rights
Questo capitolo esamina il ruolo della Corte di Giustizia dell'Unione Europea (CGUE) nella tutela dei diritti delle persone con disabilità attraverso una lente "relazionale". Vengono analizzate criticamente le sentenze chiave della CGUE relative alla nozione di "lavoratore", alla definizione di "disabilità", agli obblighi di adeguamento ragionevole e alla discriminazione tra categorie di persone con disabilità. L'autore sottolinea l'approccio talvolta incerto della Corte, oscillante tra un'interpretazione estensiva dei diritti e una certa cautela nel non invadere le competenze degli Stati membri. Vengono evidenziate alcune aree trascurate, come i diritti delle madri non partorienti e dei principali caregivers di minori con gravi disabilità. Il capitolo si conclude con una riflessione sul ruolo potenzialmente più incisivo che la Commissione Europea potrebbe svolgere nel plasmare il diritto dell'UE in materia di disabilità, promuovendo un'applicazione più uniforme e un maggiore accesso alla giustizia. Un'epilogo personale rivela il conflitto di interessi dell'autore come genitore di un minore con disabilità grave. ** This chapter examines the role of the Court of Justice of the European Union (CJEU) in protecting the rights of persons with disabilities through a "relational" lens. It critically analyzes key CJEU rulings relating to the notion of "worker", the definition of "disability", the duty of reasonable accommodation, and discrimination between categories of persons with disabilities. The author highlights the Court's sometimes uncertain approach, oscillating between an extensive interpretation of rights and caution in not encroaching on Member States' competences. Some neglected areas are highlighted, such as the rights of non-birthing mothers and primary caregivers of children with severe disabilities. The chapter concludes with a reflection on the potentially more incisive role the European Commission could play in shaping EU disability law, promoting more uniform application and greater access to justice. A personal epilogue reveals the author's conflict of interest as a parent of a child with severe disability
S. Vaccari, Commento all’art. 43 c.p.a. (Motivi aggiunti), in G. Falcon, B. Marchetti, F. Cortese (a cura di), Commentario breve al Codice del processo amministrativo, Padova, Cedam, 2021, p. 467 e ss
Commento all'art. 43 C.P.A. (Motivi aggiunti
Are concerns about DSM-5 ADHD criteria supported by empirical evidence?
Thomas and colleagues are worried about the recent change in the maximum age of symptom onset in the diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) from 7 years in the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) to 12 years in DSM-5.1 2 3 They think that this change may increase “the risk of confusing ADHD with normal developmental processes, such as pubertal restlessness and distractibility.” Although it is a legitimate concern, I am not aware of any empirical evidence to support it.Indeed, a study of 2232 British children showed that extending the age of onset from 7 to 12 years increases the prevalence of ADHD by only 0.1%.4 If this change had led to non-pathological behaviours being diagnosed as ADHD, a bigger increase in prevalence would be expected. Children diagnosed with ADHD before and after 7 years also had similar clinical profiles and ADHD risk factors.4This recent change in the age of onset criterion was aimed at reducing false negative diagnoses in adults. Only half of adults assessed for ADHD recall onset of symptoms before age 7; 95% report onset before age 12.5 The UK study suggested that adults who retrospectively reported onset of ADHD between 7 and 12 years probably had symptoms before 7 years.4 Therefore, keeping the age of onset criterion at 7 years would contribute to underdiagnosis in a substantial number of adults.Finally, to avoid labelling transitory processes as ADHD, DSM-5 criteria specify that “symptoms have persisted for at least 6 months to a degree that is inconsistent with developmental level.” DSM-5 criteria are therefore unlikely to increase the risk of misdiagnosing pubertal restlessness and distractibility as ADHD. However, as Thomas and colleagues note,1 pubertal restlessness and distractibility should be considered in the differential diagnosis of ADHD.<br/
Guidance on conducting systematic reviews/meta-analyses of pharmacoepidemiological studies of safety outcomes: the gap is now filled
Until recently, no comprehensive guidance specifically on the conduction of systematic reviews and meta-analyses of pharmacoepidemiological studies of safety outcomes was available. In December 2015, the European Network of Centres for Pharmacoepidemiology and Pharamacovigilance (ENCePP), a network coordinated by the European Medicines Agency, published their ‘Guidance on conducting systematic reviews and meta-analyses of completed comparative pharmacoepidemiological studies of safety outcomes’, filling an important gap in the field. This paper highlights the ENCePP recommendations in terms of study identification, data extraction, study quality appraisal and analytical plan. Although the ENCePP document should not be considered as definitive, since it will likely be refined following researchers’ feedback, it is expected that it will be highly influential and useful for the field, with the ultimate goal to improve and standardise the conduction and reporting of systematic reviews/meta-analyses of pharmacoepidemiological studies of safety outcomes
M. Renna, S. Vaccari, Commento all’art. 40 c.p.a. (Contenuto del ricorso), in G. Falcon, B. Marchetti, F. Cortese (a cura di), Commentario breve al Codice del processo amministrativo, Padova, Cedam, 2021, p. 433 e ss
Commento all'art. 40 c.p.a. (Contenuto del ricorso
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