1,721,427 research outputs found
Perioperative Complications of Esophageal Atresia
No full textCurrent survival rate of infants with esophageal atresia with/without tracheoesophageal fistula (EA/TEF) exceeds 90% and great interest is dedicated to the long-term outcomes and complications. However, perioperative complications represent a significant burden to the EA/TEF infants and a technical challenge for the surgeon. In this review, we will focus on the most frequent perioperative complications specific of EA/TEF to describe their predisposing factors, possible preventive measures, and treatment options
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Meconium Ileus
No full textMeconium ileus (MI) is an intestinal obstruction caused by thickened meconium, strictly linked to cystic fibrosis (CF) and often representing its first manifestation. Meconium ileus can be either simple (intraluminal occlusion by stick meconium) or complex, with volvulus, atresia, necrosis, perforation, meconium peritonitis, and pseudocyst formation. Since its first description in the nineteenth century, progress was made in the understanding of the genetic origins of this disorder, leading to the identification of the CFTR gene and its over 1900 pathogenetic mutations. The diagnostic workup has seen the evolution of prenatal and postnatal imaging and laboratory studies improving the ability to early detect MI and CF and to differentiate MI from other causes of neonatal intestinal occlusion. Finally, the development of several treatment options, both surgical and nonsurgical, gives the surgeon the opportunity to tailor the therapeutic strategy to the clinical presentation of each single patient. This chapter on MI will review the current knowledge about its pathogenesis, describe the diagnostic and therapeutic approaches to the fetus and newborn baby with this disorder, and illustrate the outcomes of such patients that may aid the pediatric surgeon in caring for these patients
Reinforced concrete elements in crack stage subjected to chloride-rich environment
No full textThe durability of reinforced concrete (RC) structures is the main challenge to overcome for global sustainability. Crack width plays an important role through which aggressive agents can penetrate and initiation of corrosion begins. Several researchers have looked into the relationship between crack width and corrosion level, but there has yet to be agreement among the authors. With this aim in mind, 31 tension ties (90 mm x 90 mm x 830 mm) with Ø12 rebar were cast, pre-cracked to different crack widths, subjected to permanent tensile load and exposed to wet and dry cycles of water containing 3.5% NaCl solution for 280 days. The experimental results show that the corrosion initiation began after the first cycle (except for a small delay in the sample with a 0.1 mm crack width). Currently, our focus is on evaluating corrosion propagation. Tension ties are going to be cut to extract rebar, measure pitting corrosion, and analyse the relation between crack width and corrosion
The sperm DNA fragmentation study group (SFRAG) guideline and its relevance for practicing gynecologists
No full textThis editorial highlights the key recommendations of the novel evidence-based Sperm DNA Fragmentation Guideline (SFRAG guideline) for gynecologists providing infertility care. Sperm DNA fragmentation is a biomarker of sperm’s chromatin quality. Elevated sperm DNA fragmentation rates contribute to couple’s infertility and negatively impact medically assisted reproduction outcomes. There are five main clinical scenarios in which gynecologists should consider sperm DNA fragmentation testing to guide their decision-making process. They include unexplained infertility, recurrent pregnancy loss, before (or after failed) medically assisted reproduction, and the presence of male infertility risk factors. The SFRAG guideline emphasizes the importance of corrective measures to decrease sperm DNA fragmentation rates and selection of the best medically assisted reproduction modality for the affected couples. The intended goal is to provide the foundation for standardizing care in this area while maintaining clinicians’ autonomy
Narrazione ed esperienza nell'autobiografia di un chirurgo: i voyages di Ambroise Paré (1510-1590)
No full textAutobiografia di un chirurgo del Rinasciment
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