1,720,961 research outputs found
A GENOMIC CLONE CONTAINING SEQUENCES CODING FOR BOVINE SEMINAL RIBONUCLEASE - PRELIMINARY CHARACTERIZATION
IDENTIFICATION OF AN OPEN READING FRAME CODING FOR A PANCREATIC TYPE RIBONUCLEASE IN THE OX GENOME
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A Case Study of Familiar Gastrointestinal Pathologies at Risk of Cancer. Early Detection of Degenerative Signals by Oxidative Stress Biomarkers
Beyond factors such as smoking and obesity, the risk of getting
gastrointestinal cancer is passed down from parents to offspring, inherited
by a gene mutation, predisposing them to develop cancer in their lifetime.
Here we describe the clinical history of family members affected by
gastrointestinal pathologies often leading to cancer. In the epidemiological
study, the cohort of members of this family shared a high risk of developing
gastrointestinal diseases. The subjects were monitored from May 2006 to
December 2017 by collecting periodically clinical and endoscopic data,
and determining both auto-modification of lymphocyte Poly (ADP-ribose)
Polymerase as early signal of DNA damage, and erythrocyte membrane
lipid composition (Fat Profile). Both biomarkers were demonstrated to be
non invasive and easy tools, to monitor over time family members, first
the oldest members (nine siblings), and thereafter their offspring, whose
cell status evolved from physiological even to cancerous one. All subjects
developed gastrointestinal pathologies of different kind and seriousness.
Some diseases evolved to cancer, sometimes as a sudden and lethal event.
The results of the two molecular approaches, were in agreement and even
predicted the clinical and imaging paths. This cohort study supported the
hypothesis that both non-invasive molecular analyses can predict altered
cell states and support clinical and imaging tests
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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